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Items: 1 to 20 of 290

1.

The role of human Dicer-dsRBD in processing small regulatory RNAs.

Wostenberg C, Lary JW, Sahu D, Acevedo R, Quarles KA, Cole JL, Showalter SA.

PLoS One. 2012;7(12):e51829. doi: 10.1371/journal.pone.0051829. Epub 2012 Dec 13.

2.

Dynamic origins of differential RNA binding function in two dsRBDs from the miRNA "microprocessor" complex.

Wostenberg C, Quarles KA, Showalter SA.

Biochemistry. 2010 Dec 21;49(50):10728-36. doi: 10.1021/bi1015716. Epub 2010 Nov 22.

3.

Substrate-specific kinetics of Dicer-catalyzed RNA processing.

Chakravarthy S, Sternberg SH, Kellenberger CA, Doudna JA.

J Mol Biol. 2010 Dec 3;404(3):392-402. doi: 10.1016/j.jmb.2010.09.030. Epub 2010 Oct 13.

4.

Single processing center models for human Dicer and bacterial RNase III.

Zhang H, Kolb FA, Jaskiewicz L, Westhof E, Filipowicz W.

Cell. 2004 Jul 9;118(1):57-68.

5.

The siRNA suppressor RTL1 is redox-regulated through glutathionylation of a conserved cysteine in the double-stranded-RNA-binding domain.

Charbonnel C, Niazi AK, Elvira-Matelot E, Nowak E, Zytnicki M, de Bures A, Jobet E, Opsomer A, Shamandi N, Nowotny M, Carapito C, Reichheld JP, Vaucheret H, Sáez-Vásquez J.

Nucleic Acids Res. 2017 Nov 16;45(20):11891-11907. doi: 10.1093/nar/gkx820.

6.

The contributions of dsRNA structure to Dicer specificity and efficiency.

Vermeulen A, Behlen L, Reynolds A, Wolfson A, Marshall WS, Karpilow J, Khvorova A.

RNA. 2005 May;11(5):674-82. Epub 2005 Apr 5.

7.

Substrate-specific structural rearrangements of human Dicer.

Taylor DW, Ma E, Shigematsu H, Cianfrocco MA, Noland CL, Nagayama K, Nogales E, Doudna JA, Wang HW.

Nat Struct Mol Biol. 2013 Jun;20(6):662-70. doi: 10.1038/nsmb.2564. Epub 2013 Apr 28.

8.

The role of PACT in the RNA silencing pathway.

Lee Y, Hur I, Park SY, Kim YK, Suh MR, Kim VN.

EMBO J. 2006 Feb 8;25(3):522-32. Epub 2006 Jan 19.

9.

Viral RNAi suppressor reversibly binds siRNA to outcompete Dicer and RISC via multiple turnover.

Rawlings RA, Krishnan V, Walter NG.

J Mol Biol. 2011 Apr 29;408(2):262-76. doi: 10.1016/j.jmb.2011.02.038. Epub 2011 Feb 24.

10.

Deformability in the cleavage site of primary microRNA is not sensed by the double-stranded RNA binding domains in the microprocessor component DGCR8.

Quarles KA, Chadalavada D, Showalter SA.

Proteins. 2015 Jun;83(6):1165-79. doi: 10.1002/prot.24810. Epub 2015 Apr 28.

11.

Helical defects in microRNA influence protein binding by TAR RNA binding protein.

Acevedo R, Orench-Rivera N, Quarles KA, Showalter SA.

PLoS One. 2015 Jan 21;10(1):e0116749. doi: 10.1371/journal.pone.0116749. eCollection 2015.

12.

A human, ATP-independent, RISC assembly machine fueled by pre-miRNA.

Maniataki E, Mourelatos Z.

Genes Dev. 2005 Dec 15;19(24):2979-90.

13.

Modeling of the catalytic core of Arabidopsis thaliana Dicer-like 4 protein and its complex with double-stranded RNA.

Mickiewicz A, Sarzyńska J, Miłostan M, Kurzyńska-Kokorniak A, Rybarczyk A, Łukasiak P, Kuliński T, Figlerowicz M, Błażewicz J.

Comput Biol Chem. 2017 Feb;66:44-56. doi: 10.1016/j.compbiolchem.2016.11.003. Epub 2016 Nov 17.

PMID:
27907832
14.

Human RISC couples microRNA biogenesis and posttranscriptional gene silencing.

Gregory RI, Chendrimada TP, Cooch N, Shiekhattar R.

Cell. 2005 Nov 18;123(4):631-40. Epub 2005 Nov 3.

15.

How short RNAs impact the human ribonuclease Dicer activity: putative regulatory feedback-loops and other RNA-mediated mechanisms controlling microRNA processing.

Koralewska N, Hoffmann W, Pokornowska M, Milewski M, Lipinska A, Bienkowska-Szewczyk K, Figlerowicz M, Kurzynska-Kokorniak A.

Acta Biochim Pol. 2016;63(4):773-783. Epub 2016 Oct 13.

16.

A universal small molecule, inorganic phosphate, restricts the substrate specificity of Dicer-2 in small RNA biogenesis.

Fukunaga R, Zamore PD.

Cell Cycle. 2014;13(11):1671-6. doi: 10.4161/cc.29066. Epub 2014 Apr 30.

17.

Engineering double-stranded RNA binding activity into the Drosha double-stranded RNA binding domain results in a loss of microRNA processing function.

Kranick JC, Chadalavada DM, Sahu D, Showalter SA.

PLoS One. 2017 Aug 8;12(8):e0182445. doi: 10.1371/journal.pone.0182445. eCollection 2017.

18.

The double-stranded RNA binding domain of human Dicer functions as a nuclear localization signal.

Doyle M, Badertscher L, Jaskiewicz L, Güttinger S, Jurado S, Hugenschmidt T, Kutay U, Filipowicz W.

RNA. 2013 Sep;19(9):1238-52. doi: 10.1261/rna.039255.113. Epub 2013 Jul 23.

19.

Structure of a yeast RNase III dsRBD complex with a noncanonical RNA substrate provides new insights into binding specificity of dsRBDs.

Wang Z, Hartman E, Roy K, Chanfreau G, Feigon J.

Structure. 2011 Jul 13;19(7):999-1010. doi: 10.1016/j.str.2011.03.022.

20.

Structural basis for recognition of the AGNN tetraloop RNA fold by the double-stranded RNA-binding domain of Rnt1p RNase III.

Wu H, Henras A, Chanfreau G, Feigon J.

Proc Natl Acad Sci U S A. 2004 Jun 1;101(22):8307-12. Epub 2004 May 18.

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