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Items: 1 to 20 of 106

1.

Virtual screening and biological evaluation of inhibitors targeting the XPA-ERCC1 interaction.

Barakat KH, Jordheim LP, Perez-Pineiro R, Wishart D, Dumontet C, Tuszynski JA.

PLoS One. 2012;7(12):e51329. doi: 10.1371/journal.pone.0051329. Epub 2012 Dec 14.

2.

New design of nucleotide excision repair (NER) inhibitors for combination cancer therapy.

Gentile F, Tuszynski JA, Barakat KH.

J Mol Graph Model. 2016 Apr;65:71-82. doi: 10.1016/j.jmgm.2016.02.010. Epub 2016 Feb 26.

PMID:
26939044
3.

Inhibition of nucleotide excision repair by anti-XPA monoclonal antibodies which interfere with binding to RPA, ERCC1, and TFIIH.

Saijo M, Matsuda T, Kuraoka I, Tanaka K.

Biochem Biophys Res Commun. 2004 Sep 3;321(4):815-22.

PMID:
15358100
4.

Functional and physical interactions between ERCC1 and MSH2 complexes for resistance to cis-diamminedichloroplatinum(II) in mammalian cells.

Lan L, Hayashi T, Rabeya RM, Nakajima S, Kanno Si, Takao M, Matsunaga T, Yoshino M, Ichikawa M, Riele Ht, Tsuchiya S, Tanaka K, Yasui A.

DNA Repair (Amst). 2004 Feb 3;3(2):135-43.

PMID:
14706347
6.

The XPA-binding domain of ERCC1 is required for nucleotide excision repair but not other DNA repair pathways.

Orelli B, McClendon TB, Tsodikov OV, Ellenberger T, Niedernhofer LJ, Schärer OD.

J Biol Chem. 2010 Feb 5;285(6):3705-12. doi: 10.1074/jbc.M109.067538. Epub 2009 Nov 23.

8.
9.

Characterization of an inhibitory dynamic pharmacophore for the ERCC1-XPA interaction using a combined molecular dynamics and virtual screening approach.

Barakat KH, Torin Huzil J, Luchko T, Jordheim L, Dumontet C, Tuszynski J.

J Mol Graph Model. 2009 Sep;28(2):113-30. doi: 10.1016/j.jmgm.2009.04.009. Epub 2009 May 4.

PMID:
19473860
10.

Cyclosporin A inhibits nucleotide excision repair via downregulation of the xeroderma pigmentosum group A and G proteins, which is mediated by calcineurin inhibition.

Kuschal C, Thoms KM, Boeckmann L, Laspe P, Apel A, Schön MP, Emmert S.

Exp Dermatol. 2011 Oct;20(10):795-9. doi: 10.1111/j.1600-0625.2011.01320.x. Epub 2011 Jun 24.

PMID:
21707758
11.

Mitotic regulator Nlp interacts with XPA/ERCC1 complexes and regulates nucleotide excision repair (NER) in response to UV radiation.

Ma XJ, Shang L, Zhang WM, Wang MR, Zhan QM.

Cancer Lett. 2016 Apr 10;373(2):214-21. doi: 10.1016/j.canlet.2016.01.020. Epub 2016 Jan 19.

PMID:
26805762
12.

Structural basis for the recruitment of ERCC1-XPF to nucleotide excision repair complexes by XPA.

Tsodikov OV, Ivanov D, Orelli B, Staresincic L, Shoshani I, Oberman R, Schärer OD, Wagner G, Ellenberger T.

EMBO J. 2007 Nov 14;26(22):4768-76. Epub 2007 Oct 18.

13.

DNA repair gets physical: mapping an XPA-binding site on ERCC1.

Croteau DL, Peng Y, Van Houten B.

DNA Repair (Amst). 2008 May 3;7(5):819-26. doi: 10.1016/j.dnarep.2008.01.018. Epub 2008 Mar 14. Review.

14.

Enhancement of damage-specific DNA binding of XPA by interaction with the ERCC1 DNA repair protein.

Nagai A, Saijo M, Kuraoka I, Matsuda T, Kodo N, Nakatsu Y, Mimaki T, Mino M, Biggerstaff M, Wood RD, et al.

Biochem Biophys Res Commun. 1995 Jun 26;211(3):960-6.

PMID:
7598728
15.

Xeroderma pigmentosum group A protein loads as a separate factor onto DNA lesions.

Rademakers S, Volker M, Hoogstraten D, Nigg AL, Moné MJ, Van Zeeland AA, Hoeijmakers JH, Houtsmuller AB, Vermeulen W.

Mol Cell Biol. 2003 Aug;23(16):5755-67.

16.

Identification of novel small molecule inhibitors of the XPA protein using in silico based screening.

Neher TM, Shuck SC, Liu JY, Zhang JT, Turchi JJ.

ACS Chem Biol. 2010 Oct 15;5(10):953-65. doi: 10.1021/cb1000444.

17.

Mutations in XPA that prevent association with ERCC1 are defective in nucleotide excision repair.

Li L, Peterson CA, Lu X, Legerski RJ.

Mol Cell Biol. 1995 Apr;15(4):1993-8.

18.

XPA protein as a limiting factor for nucleotide excision repair and UV sensitivity in human cells.

Köberle B, Roginskaya V, Wood RD.

DNA Repair (Amst). 2006 May 10;5(5):641-8. Epub 2006 Jan 18.

PMID:
16413230
19.

Expression of domains for protein-protein interaction of nucleotide excision repair proteins modifies cancer cell sensitivity to platinum derivatives and genomic stability.

Jordheim LP, Cros-Perrial E, Matera EL, Bouledrak K, Dumontet C.

Clin Exp Pharmacol Physiol. 2014 Oct;41(10):817-24. doi: 10.1111/1440-1681.12282.

PMID:
25115435
20.

Nucleotide excision repair by mutant xeroderma pigmentosum group A (XPA) proteins with deficiency in interaction with RPA.

Saijo M, Takedachi A, Tanaka K.

J Biol Chem. 2011 Feb 18;286(7):5476-83. doi: 10.1074/jbc.M110.172916. Epub 2010 Dec 9.

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