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Items: 1 to 20 of 359

1.

Hes repressors are essential regulators of hematopoietic stem cell development downstream of Notch signaling.

Guiu J, Shimizu R, D'Altri T, Fraser ST, Hatakeyama J, Bresnick EH, Kageyama R, Dzierzak E, Yamamoto M, Espinosa L, Bigas A.

J Exp Med. 2013 Jan 14;210(1):71-84. doi: 10.1084/jem.20120993. Epub 2012 Dec 24.

2.

Cooperative functions of Hes/Hey genes in auditory hair cell and supporting cell development.

Tateya T, Imayoshi I, Tateya I, Ito J, Kageyama R.

Dev Biol. 2011 Apr 15;352(2):329-40. doi: 10.1016/j.ydbio.2011.01.038. Epub 2011 Feb 16.

3.

RBPjkappa-dependent Notch function regulates Gata2 and is essential for the formation of intra-embryonic hematopoietic cells.

Robert-Moreno A, Espinosa L, de la Pompa JL, Bigas A.

Development. 2005 Mar;132(5):1117-26. Epub 2005 Feb 2.

4.

Hes1 and Hes5 regulate vascular remodeling and arterial specification of endothelial cells in brain vascular development.

Kitagawa M, Hojo M, Imayoshi I, Goto M, Ando M, Ohtsuka T, Kageyama R, Miyamoto S.

Mech Dev. 2013 Sep-Oct;130(9-10):458-66. doi: 10.1016/j.mod.2013.07.001. Epub 2013 Jul 17.

5.

ETO, but not leukemogenic fusion protein AML1/ETO, augments RBP-Jkappa/SHARP-mediated repression of notch target genes.

Salat D, Liefke R, Wiedenmann J, Borggrefe T, Oswald F.

Mol Cell Biol. 2008 May;28(10):3502-12. doi: 10.1128/MCB.01966-07. Epub 2008 Mar 10.

6.

Identification of Cdca7 as a novel Notch transcriptional target involved in hematopoietic stem cell emergence.

Guiu J, Bergen DJ, De Pater E, Islam AB, Ayllón V, Gama-Norton L, Ruiz-Herguido C, González J, López-Bigas N, Menendez P, Dzierzak E, Espinosa L, Bigas A.

J Exp Med. 2014 Nov 17;211(12):2411-23. doi: 10.1084/jem.20131857. Epub 2014 Nov 10.

7.

ATF2 maintains a subset of neural progenitors through CBF1/Notch independent Hes-1 expression and synergistically activates the expression of Hes-1 in Notch-dependent neural progenitors.

Sanalkumar R, Indulekha CL, Divya TS, Divya MS, Anto RJ, Vinod B, Vidyanand S, Jagatha B, Venugopal S, James J.

J Neurochem. 2010 May;113(4):807-18. doi: 10.1111/j.1471-4159.2010.06574.x. Epub 2010 Jan 8.

9.

Ikaros represses the transcriptional response to Notch signaling in T-cell development.

Kleinmann E, Geimer Le Lay AS, Sellars M, Kastner P, Chan S.

Mol Cell Biol. 2008 Dec;28(24):7465-75. doi: 10.1128/MCB.00715-08. Epub 2008 Oct 13.

10.

Notch signaling regulates the FOXP3 promoter through RBP-J- and Hes1-dependent mechanisms.

Ou-Yang HF, Zhang HW, Wu CG, Zhang P, Zhang J, Li JC, Hou LH, He F, Ti XY, Song LQ, Zhang SZ, Feng L, Qi HW, Han H.

Mol Cell Biochem. 2009 Jan;320(1-2):109-14. doi: 10.1007/s11010-008-9912-4. Epub 2008 Sep 6.

PMID:
18777163
11.

Notch-Rbpj signaling is required for the development of noradrenergic neurons in the mouse locus coeruleus.

Shi M, Hu ZL, Zheng MH, Song NN, Huang Y, Zhao G, Han H, Ding YQ.

J Cell Sci. 2012 Sep 15;125(Pt 18):4320-32. doi: 10.1242/jcs.102152. Epub 2012 Jun 20.

12.

Hes1 suppresses acute myeloid leukemia development through FLT3 repression.

Kato T, Sakata-Yanagimoto M, Nishikii H, Ueno M, Miyake Y, Yokoyama Y, Asabe Y, Kamada Y, Muto H, Obara N, Suzukawa K, Hasegawa Y, Kitabayashi I, Uchida K, Hirao A, Yagita H, Kageyama R, Chiba S.

Leukemia. 2015 Mar;29(3):576-85. doi: 10.1038/leu.2014.281. Epub 2014 Sep 19.

PMID:
25234168
13.

Stochastic simulation of notch signaling reveals novel factors that mediate the differentiation of neural stem cells.

Tzou WS, Lo YT, Pai TW, Hu CH, Li CH.

J Comput Biol. 2014 Jul;21(7):548-67. doi: 10.1089/cmb.2014.0022. Epub 2014 May 5.

14.

HES1 inhibits cycling of hematopoietic progenitor cells via DNA binding.

Yu X, Alder JK, Chun JH, Friedman AD, Heimfeld S, Cheng L, Civin CI.

Stem Cells. 2006 Apr;24(4):876-88. Epub 2006 Mar 2.

15.

Notch activity is downregulated just prior to retinal ganglion cell differentiation.

Nelson BR, Gumuscu B, Hartman BH, Reh TA.

Dev Neurosci. 2006;28(1-2):128-41.

PMID:
16508310
16.

Notch-HES1 signaling axis controls hemato-endothelial fate decisions of human embryonic and induced pluripotent stem cells.

Lee JB, Werbowetski-Ogilvie TE, Lee JH, McIntyre BA, Schnerch A, Hong SH, Park IH, Daley GQ, Bernstein ID, Bhatia M.

Blood. 2013 Aug 15;122(7):1162-73. doi: 10.1182/blood-2012-12-471649. Epub 2013 Jun 3.

17.

Persistent expression of activated notch in the developing hypothalamus affects survival of pituitary progenitors and alters pituitary structure.

Aujla PK, Bogdanovic V, Naratadam GT, Raetzman LT.

Dev Dyn. 2015 Aug;244(8):921-34. doi: 10.1002/dvdy.24283.

18.

Gata2 cis-element is required for hematopoietic stem cell generation in the mammalian embryo.

Gao X, Johnson KD, Chang YI, Boyer ME, Dewey CN, Zhang J, Bresnick EH.

J Exp Med. 2013 Dec 16;210(13):2833-42. doi: 10.1084/jem.20130733. Epub 2013 Dec 2.

19.

Genome-wide analysis of target genes regulated by HoxB4 in hematopoietic stem and progenitor cells developing from embryonic stem cells.

Oshima M, Endoh M, Endo TA, Toyoda T, Nakajima-Takagi Y, Sugiyama F, Koseki H, Kyba M, Iwama A, Osawa M.

Blood. 2011 Apr 14;117(15):e142-50. doi: 10.1182/blood-2010-12-323212. Epub 2011 Feb 22.

20.

Multiple roles of Notch signaling in the regulation of epidermal development.

Moriyama M, Durham AD, Moriyama H, Hasegawa K, Nishikawa S, Radtke F, Osawa M.

Dev Cell. 2008 Apr;14(4):594-604. doi: 10.1016/j.devcel.2008.01.017.

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