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Items: 1 to 20 of 108

1.

Signal transducer and activator of transcription 3 (STAT3) regulates collagen-induced platelet aggregation independently of its transcription factor activity.

Zhou Z, Gushiken FC, Bolgiano D, Salsbery BJ, Aghakasiri N, Jing N, Wu X, Vijayan KV, Rumbaut RE, Adachi R, Lopez JA, Dong JF.

Circulation. 2013 Jan 29;127(4):476-485. doi: 10.1161/CIRCULATIONAHA.112.132126. Epub 2012 Dec 24.

3.

Diminished contact-dependent reinforcement of Syk activation underlies impaired thrombus growth in mice lacking Semaphorin 4D.

Wannemacher KM, Zhu L, Jiang H, Fong KP, Stalker TJ, Lee D, Tran AN, Neeves KB, Maloney S, Kumanogoh A, Kikutani H, Hammer DA, Diamond SL, Brass LF.

Blood. 2010 Dec 16;116(25):5707-15. doi: 10.1182/blood-2010-04-279943. Epub 2010 Sep 20.

4.

Non-genomic effects of PPARgamma ligands: inhibition of GPVI-stimulated platelet activation.

Moraes LA, Spyridon M, Kaiser WJ, Jones CI, Sage T, Atherton RE, Gibbins JM.

J Thromb Haemost. 2010 Mar;8(3):577-87. doi: 10.1111/j.1538-7836.2009.03732.x. Epub 2009 Dec 21.

5.

Kaempferol suppresses collagen-induced platelet activation by inhibiting NADPH oxidase and protecting SHP-2 from oxidative inactivation.

Wang SB, Jang JY, Chae YH, Min JH, Baek JY, Kim M, Park Y, Hwang GS, Ryu JS, Chang TS.

Free Radic Biol Med. 2015 Jun;83:41-53. doi: 10.1016/j.freeradbiomed.2015.01.018. Epub 2015 Jan 31.

PMID:
25645952
6.
7.

Development of a pharmacodynamic assay based on PLCγ2 phosphorylation for quantifying spleen tyrosine kinase (SYK)-Bruton's tyrosine kinase (BTK) signaling.

Hsu J, Zhang J, Kitson C, Tan SL, Narula S, DeMartino JA, Liao C.

J Biomol Screen. 2013 Sep;18(8):890-8. doi: 10.1177/1087057113489881. Epub 2013 May 23.

PMID:
23704133
8.

The Fc receptor gamma-chain and the tyrosine kinase Syk are essential for activation of mouse platelets by collagen.

Poole A, Gibbins JM, Turner M, van Vugt MJ, van de Winkel JG, Saito T, Tybulewicz VL, Watson SP.

EMBO J. 1997 May 1;16(9):2333-41.

9.
10.

The toll-like receptor 2/1 (TLR2/1) complex initiates human platelet activation via the src/Syk/LAT/PLCγ2 signalling cascade.

Fälker K, Klarström-Engström K, Bengtsson T, Lindahl TL, Grenegård M.

Cell Signal. 2014 Feb;26(2):279-86. doi: 10.1016/j.cellsig.2013.11.011. Epub 2013 Nov 12.

PMID:
24240055
11.

Differential Roles of the NADPH-Oxidase 1 and 2 in Platelet Activation and Thrombosis.

Delaney MK, Kim K, Estevez B, Xu Z, Stojanovic-Terpo A, Shen B, Ushio-Fukai M, Cho J, Du X.

Arterioscler Thromb Vasc Biol. 2016 May;36(5):846-54. doi: 10.1161/ATVBAHA.116.307308. Epub 2016 Mar 17.

12.

A critical role for the regulation of Syk from agglutination to aggregation in human platelets.

Shih CH, Chiang TB, Wang WJ.

Biochem Biophys Res Commun. 2014 Jan 10;443(2):580-5. doi: 10.1016/j.bbrc.2013.12.001. Epub 2013 Dec 8.

PMID:
24326074
13.

Syk interacts with tyrosine-phosphorylated proteins in human platelets activated by collagen and cross-linking of the Fc gamma-IIA receptor.

Yanaga F, Poole A, Asselin J, Blake R, Schieven GL, Clark EA, Law CL, Watson SP.

Biochem J. 1995 Oct 15;311 ( Pt 2):471-8. Erratum in: Biochem J 1996 Feb 1;313(Pt 3):1047.

14.

Tyrosine phosphorylation on spleen tyrosine kinase (Syk) is differentially regulated in human and murine platelets by protein kinase C isoforms.

Buitrago L, Bhavanasi D, Dangelmaier C, Manne BK, Badolia R, Borgognone A, Tsygankov AY, McKenzie SE, Kunapuli SP.

J Biol Chem. 2013 Oct 4;288(40):29160-9. doi: 10.1074/jbc.M113.464107. Epub 2013 Aug 19.

15.

Role of a Janus kinase 2-dependent signaling pathway in platelet activation.

Lu WJ, Lin KC, Huang SY, Thomas PA, Wu YH, Wu HC, Lin KH, Sheu JR.

Thromb Res. 2014 Jun;133(6):1088-96. doi: 10.1016/j.thromres.2014.03.042. Epub 2014 Apr 1.

PMID:
24731555
16.

Endocannabinoids control platelet activation and limit aggregate formation under flow.

De Angelis V, Koekman AC, Weeterings C, Roest M, de Groot PG, Herczenik E, Maas C.

PLoS One. 2014 Sep 29;9(9):e108282. doi: 10.1371/journal.pone.0108282. eCollection 2014.

17.

Role of Fc receptor gamma-chain in platelet glycoprotein Ib-mediated signaling.

Wu Y, Suzuki-Inoue K, Satoh K, Asazuma N, Yatomi Y, Berndt MC, Ozaki Y.

Blood. 2001 Jun 15;97(12):3836-45.

18.

Hinokitiol inhibits platelet activation ex vivo and thrombus formation in vivo.

Lin KH, Kuo JR, Lu WJ, Chung CL, Chou DS, Huang SY, Lee HC, Sheu JR.

Biochem Pharmacol. 2013 May 15;85(10):1478-85. doi: 10.1016/j.bcp.2013.02.027. Epub 2013 Mar 5.

PMID:
23473801
19.

CEACAM2 negatively regulates hemi (ITAM-bearing) GPVI and CLEC-2 pathways and thrombus growth in vitro and in vivo.

Alshahrani MM, Yang E, Yip J, Ghanem SS, Abdallah SL, deAngelis AM, O'Malley CJ, Moheimani F, Najjar SM, Jackson DE.

Blood. 2014 Oct 9;124(15):2431-41. doi: 10.1182/blood-2014-04-569707. Epub 2014 Aug 1.

20.

A structural basis for the inhibition of collagen-stimulated platelet function by quercetin and structurally related flavonoids.

Wright B, Moraes LA, Kemp CF, Mullen W, Crozier A, Lovegrove JA, Gibbins JM.

Br J Pharmacol. 2010 Mar;159(6):1312-25. doi: 10.1111/j.1476-5381.2009.00632.x. Epub 2010 Feb 10.

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