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Items: 1 to 20 of 92

1.

CD81 regulates cell migration through its association with Rac GTPase.

Tejera E, Rocha-Perugini V, López-Martín S, Pérez-Hernández D, Bachir AI, Horwitz AR, Vázquez J, Sánchez-Madrid F, Yáñez-Mo M.

Mol Biol Cell. 2013 Feb;24(3):261-73. doi: 10.1091/mbc.E12-09-0642. Epub 2012 Dec 21.

2.

The CD9/CD81 tetraspanin complex and tetraspanin CD151 regulate α3β1 integrin-dependent tumor cell behaviors by overlapping but distinct mechanisms.

Gustafson-Wagner E, Stipp CS.

PLoS One. 2013 Apr 17;8(4):e61834. doi: 10.1371/journal.pone.0061834. Print 2013.

3.

The tetraspanin CD81 protein increases melanoma cell motility by up-regulating metalloproteinase MT1-MMP expression through the pro-oncogenic Akt-dependent Sp1 activation signaling pathways.

Hong IK, Byun HJ, Lee J, Jin YJ, Wang SJ, Jeoung DI, Kim YM, Lee H.

J Biol Chem. 2014 May 30;289(22):15691-704. doi: 10.1074/jbc.M113.534206. Epub 2014 Apr 14.

4.

Reducing isoform complexity of human tetraspanins by optimized expression in Dictyostelium discoideum enables high-throughput functional read-out.

Scheltz T, von Bülow J, Beitz E.

Protein Expr Purif. 2017 Jul;135:8-15. doi: 10.1016/j.pep.2017.04.012. Epub 2017 Apr 22.

PMID:
28442431
5.

CD81 is essential for the formation of membrane protrusions and regulates Rac1-activation in adhesion-dependent immune cell migration.

Quast T, Eppler F, Semmling V, Schild C, Homsi Y, Levy S, Lang T, Kurts C, Kolanus W.

Blood. 2011 Aug 18;118(7):1818-27. doi: 10.1182/blood-2010-12-326595. Epub 2011 Jun 15.

6.

Tetraspanin CD151 stimulates adhesion-dependent activation of Ras, Rac, and Cdc42 by facilitating molecular association between β1 integrins and small GTPases.

Hong IK, Jeoung DI, Ha KS, Kim YM, Lee H.

J Biol Chem. 2012 Sep 14;287(38):32027-39. doi: 10.1074/jbc.M111.314443. Epub 2012 Jul 25.

7.

Structural basis of ligand interactions of the large extracellular domain of tetraspanin CD81.

Rajesh S, Sridhar P, Tews BA, Fénéant L, Cocquerel L, Ward DG, Berditchevski F, Overduin M.

J Virol. 2012 Sep;86(18):9606-16. doi: 10.1128/JVI.00559-12. Epub 2012 Jun 27.

8.

EWI-2 negatively regulates TGF-β signaling leading to altered melanoma growth and metastasis.

Wang HX, Sharma C, Knoblich K, Granter SR, Hemler ME.

Cell Res. 2015 Mar;25(3):370-85. doi: 10.1038/cr.2015.17. Epub 2015 Feb 6.

9.

The extracellular δ-domain is essential for the formation of CD81 tetraspanin webs.

Homsi Y, Schloetel JG, Scheffer KD, Schmidt TH, Destainville N, Florin L, Lang T.

Biophys J. 2014 Jul 1;107(1):100-13. doi: 10.1016/j.bpj.2014.05.028.

10.

The intracellular interactome of tetraspanin-enriched microdomains reveals their function as sorting machineries toward exosomes.

Perez-Hernandez D, Gutiérrez-Vázquez C, Jorge I, López-Martín S, Ursa A, Sánchez-Madrid F, Vázquez J, Yáñez-Mó M.

J Biol Chem. 2013 Apr 26;288(17):11649-61. doi: 10.1074/jbc.M112.445304. Epub 2013 Mar 5.

11.

CD81 controls immunity to Listeria infection through rac-dependent inhibition of proinflammatory mediator release and activation of cytotoxic T cells.

Martínez del Hoyo G, Ramírez-Huesca M, Levy S, Boucheix C, Rubinstein E, Minguito de la Escalera M, González-Cintado L, Ardavín C, Veiga E, Yáñez-Mó M, Sánchez-Madrid F.

J Immunol. 2015 Jun 15;194(12):6090-101. doi: 10.4049/jimmunol.1402957. Epub 2015 May 13.

12.
13.

Tetraspanins CD81 and CD82 facilitate α4β1-mediated adhesion of human erythroblasts to vascular cell adhesion molecule-1.

Spring FA, Griffiths RE, Mankelow TJ, Agnew C, Parsons SF, Chasis JA, Anstee DJ.

PLoS One. 2013 May 21;8(5):e62654. doi: 10.1371/journal.pone.0062654. Print 2013.

14.

Significance of palmitoylation of CD81 on its association with tetraspanin-enriched microdomains and mediating hepatitis C virus cell entry.

Zhu YZ, Luo Y, Cao MM, Liu Y, Liu XQ, Wang W, Wu DG, Guan M, Xu QQ, Ren H, Zhao P, Qi ZT.

Virology. 2012 Aug 1;429(2):112-23. doi: 10.1016/j.virol.2012.03.002. Epub 2012 May 4.

15.

Regulation of endothelial cell motility by complexes of tetraspan molecules CD81/TAPA-1 and CD151/PETA-3 with alpha3 beta1 integrin localized at endothelial lateral junctions.

Yáñez-Mó M, Alfranca A, Cabañas C, Marazuela M, Tejedor R, Ursa MA, Ashman LK, de Landázuri MO, Sánchez-Madrid F.

J Cell Biol. 1998 May 4;141(3):791-804.

16.

Role of an arginine-lysine rich motif in maturation and trafficking of CD19.

Vences-Catalán F, Kuo CC, Levy S.

Biochem Biophys Res Commun. 2015 Sep 25;465(3):319-23. doi: 10.1016/j.bbrc.2015.06.129. Epub 2015 Jun 23.

PMID:
26111452
17.

Rac1 and Rac3 isoform activation is involved in the invasive and metastatic phenotype of human breast cancer cells.

Baugher PJ, Krishnamoorthy L, Price JE, Dharmawardhane SF.

Breast Cancer Res. 2005;7(6):R965-74. Epub 2005 Sep 30.

18.

Plasma Membrane Tetraspanin CD81 Complexes with Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) and Low Density Lipoprotein Receptor (LDLR), and Its Levels Are Reduced by PCSK9.

Le QT, Blanchet M, Seidah NG, Labonté P.

J Biol Chem. 2015 Sep 18;290(38):23385-400. doi: 10.1074/jbc.M115.642991. Epub 2015 Jul 20.

19.

A mutation in the human tetraspanin CD81 gene is expressed as a truncated protein but does not enable CD19 maturation and cell surface expression.

Vences-Catalán F, Kuo CC, Sagi Y, Chen H, Kela-Madar N, van Zelm MC, van Dongen JJ, Levy S.

J Clin Immunol. 2015 Apr;35(3):254-63. doi: 10.1007/s10875-015-0148-2. Epub 2015 Mar 6.

PMID:
25739915
20.

FRL, a novel formin-related protein, binds to Rac and regulates cell motility and survival of macrophages.

Yayoshi-Yamamoto S, Taniuchi I, Watanabe T.

Mol Cell Biol. 2000 Sep;20(18):6872-81.

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