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Items: 1 to 20 of 116

1.

Engineering the substrate specificity of a thermophilic penicillin acylase from thermus thermophilus.

Torres LL, Cantero A, del Valle M, Marina A, López-Gallego F, Guisán JM, Berenguer J, Hidalgo A.

Appl Environ Microbiol. 2013 Mar;79(5):1555-62. doi: 10.1128/AEM.03215-12. Epub 2012 Dec 21.

2.

Functional expression of a penicillin acylase from the extreme thermophile Thermus thermophilus HB27 in Escherichia coli.

Torres LL, Ferreras ER, Cantero A, Hidalgo A, Berenguer J.

Microb Cell Fact. 2012 Aug 9;11:105. doi: 10.1186/1475-2859-11-105.

3.

Crystal structures of penicillin acylase enzyme-substrate complexes: structural insights into the catalytic mechanism.

McVey CE, Walsh MA, Dodson GG, Wilson KS, Brannigan JA.

J Mol Biol. 2001 Oct 12;313(1):139-50.

PMID:
11601852
4.

Penicillin acylase mutants with altered site-directed activity from Kluyvera citrophila.

Prieto I, Martín J, Arche R, Fernández P, Pérez-Aranda A, Barbero JL.

Appl Microbiol Biotechnol. 1990 Aug;33(5):553-9.

PMID:
1366784
5.

Crystal structure of penicillin G acylase from the Bro1 mutant strain of Providencia rettgeri.

McDonough MA, Klei HE, Kelly JA.

Protein Sci. 1999 Oct;8(10):1971-81.

6.

Characterization of the beta-lactam binding site of penicillin acylase of Escherichia coli by structural and site-directed mutagenesis studies.

Alkema WB, Hensgens CM, Kroezinga EH, de Vries E, Floris R, van der Laan JM, Dijkstra BW, Janssen DB.

Protein Eng. 2000 Dec;13(12):857-63.

PMID:
11239085
7.

Role of alphaArg145 and betaArg263 in the active site of penicillin acylase of Escherichia coli.

Alkema WB, Prins AK, de Vries E, Janssen DB.

Biochem J. 2002 Jul 1;365(Pt 1):303-9.

8.

Improved activity and pH stability of E. coli ATCC 11105 penicillin acylase by error-prone PCR.

Balci H, Ozturk MT, Pijning T, Ozturk SI, Gumusel F.

Appl Microbiol Biotechnol. 2014 May;98(10):4467-77. doi: 10.1007/s00253-013-5476-7. Epub 2014 Jan 5.

PMID:
24389703
9.

Strategic manipulation of an industrial biocatalyst--evolution of a cephalosporin C acylase.

Conti G, Pollegioni L, Molla G, Rosini E.

FEBS J. 2014 May;281(10):2443-55. doi: 10.1111/febs.12798. Epub 2014 Apr 22.

10.

A new role for penicillin acylases: degradation of acyl homoserine lactone quorum sensing signals by Kluyvera citrophila penicillin G acylase.

Mukherji R, Varshney NK, Panigrahi P, Suresh CG, Prabhune A.

Enzyme Microb Technol. 2014 Mar 5;56:1-7. doi: 10.1016/j.enzmictec.2013.12.010. Epub 2013 Dec 19.

PMID:
24564895
11.

Mutational analysis of a key residue in the substrate specificity of a cephalosporin acylase.

Otten LG, Sio CF, van der Sloot AM, Cool RH, Quax WJ.

Chembiochem. 2004 Jun 7;5(6):820-5.

PMID:
15174165
12.

Substrate specificity of penicillin acylase from Streptomyces lavendulae.

Torres-Guzmán R, de la Mata I, Torres-Bacete J, Arroyo M, Castillón MP, Acebal C.

Biochem Biophys Res Commun. 2002 Mar 1;291(3):593-7.

PMID:
11855830
13.

Effects of catalytic site mutations on active expression of phage fused penicillin acylase.

Shi YF, Soumillion P, Ueda M.

J Biotechnol. 2010 Jan 15;145(2):139-42. doi: 10.1016/j.jbiotec.2009.11.009. Epub 2009 Nov 20.

PMID:
19932137
14.

Kinetic study of penicillin acylase from Alcaligenes faecalis.

Svedas V, Guranda D, van Langen L, van Rantwijk F, Sheldon R.

FEBS Lett. 1997 Nov 17;417(3):414-8.

15.

Improving the diastereoselectivity of penicillin G acylase for ampicillin synthesis from racemic substrates.

Deaguero AL, Blum JK, Bommarius AS.

Protein Eng Des Sel. 2012 Mar;25(3):135-44. doi: 10.1093/protein/gzr065. Epub 2012 Jan 22.

PMID:
22271751
16.

[Effect of mutagenesis at Ser 177 residue in penicillin G acylase on activity of the enzyme].

Wang M, Fei JA, Guo LH, Zhang QJ.

Shi Yan Sheng Wu Xue Bao. 1991 Mar;24(1):51-4. Chinese.

PMID:
1903233
18.

Modifying the substrate specificity of penicillin G acylase to cephalosporin acylase by mutating active-site residues.

Oh B, Kim K, Park J, Yoon J, Han D, Kim Y.

Biochem Biophys Res Commun. 2004 Jun 25;319(2):486-92.

PMID:
15178432
19.

Thermodynamic profiles of penicillin G hydrolysis catalyzed by wild-type and Met----Ala168 mutant penicillin acylases from Kluyvera citrophila.

Martín J, Prieto I, Barbero JL, Pérez-Gil J, Mancheño JM, Arche R.

Biochim Biophys Acta. 1990 Feb 9;1037(2):133-9.

PMID:
2306469
20.

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