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Growth differentiation factor 15 impairs aortic contractile and relaxing function through altered caveolar signaling of the endothelium.

Mazagova M, Buikema H, Landheer SW, Vavrinec P, Buiten Av, Henning RH, Deelman LE.

Am J Physiol Heart Circ Physiol. 2013 Mar 1;304(5):H709-18. doi: 10.1152/ajpheart.00543.2012.


Neuronal nitric oxide synthase-derived hydrogen peroxide is a major endothelium-dependent relaxing factor.

Capettini LS, Cortes SF, Gomes MA, Silva GA, Pesquero JL, Lopes MJ, Teixeira MM, Lemos VS.

Am J Physiol Heart Circ Physiol. 2008 Dec;295(6):H2503-11. doi: 10.1152/ajpheart.00731.2008.


Role of caveolar compartmentation in endothelium-derived hyperpolarizing factor-mediated relaxation: Ca2+ signals and gap junction function are regulated by caveolin in endothelial cells.

Saliez J, Bouzin C, Rath G, Ghisdal P, Desjardins F, Rezzani R, Rodella LF, Vriens J, Nilius B, Feron O, Balligand JL, Dessy C.

Circulation. 2008 Feb 26;117(8):1065-74. doi: 10.1161/CIRCULATIONAHA.107.731679.


Genetic deletion of growth differentiation factor 15 augments renal damage in both type 1 and type 2 models of diabetes.

Mazagova M, Buikema H, van Buiten A, Duin M, Goris M, Sandovici M, Henning RH, Deelman LE.

Am J Physiol Renal Physiol. 2013 Nov 1;305(9):F1249-64. doi: 10.1152/ajprenal.00387.2013.


Sensitivity of NOS-dependent vascular relaxation pathway to mineralocorticoid receptor blockade in caveolin-1-deficient mice.

Pojoga LH, Adamová Z, Kumar A, Stennett AK, Romero JR, Adler GK, Williams GH, Khalil RA.

Am J Physiol Heart Circ Physiol. 2010 Jun;298(6):H1776-88. doi: 10.1152/ajpheart.00661.2009.


Boldine improves endothelial function in diabetic db/db mice through inhibition of angiotensin II-mediated BMP4-oxidative stress cascade.

Lau YS, Tian XY, Mustafa MR, Murugan D, Liu J, Zhang Y, Lau CW, Huang Y.

Br J Pharmacol. 2013 Nov;170(6):1190-8. doi: 10.1111/bph.12350.


Caveolin-1 expression is critical for vascular endothelial growth factor-induced ischemic hindlimb collateralization and nitric oxide-mediated angiogenesis.

Sonveaux P, Martinive P, DeWever J, Batova Z, Daneau G, Pelat M, Ghisdal P, Grégoire V, Dessy C, Balligand JL, Feron O.

Circ Res. 2004 Jul 23;95(2):154-61.


Endothelial function in aorta segments of apolipoprotein E-deficient mice before development of atherosclerotic lesions.

Fransen P, Van Assche T, Guns PJ, Van Hove CE, De Keulenaer GW, Herman AG, Bult H.

Pflugers Arch. 2008 Feb;455(5):811-8.


Hydrogen peroxide is an endothelium-derived hyperpolarizing factor in mice.

Matoba T, Shimokawa H, Nakashima M, Hirakawa Y, Mukai Y, Hirano K, Kanaide H, Takeshita A.

J Clin Invest. 2000 Dec;106(12):1521-30.


Nitric oxide dynamics and endothelial dysfunction in type II model of genetic diabetes.

Bitar MS, Wahid S, Mustafa S, Al-Saleh E, Dhaunsi GS, Al-Mulla F.

Eur J Pharmacol. 2005 Mar 21;511(1):53-64.


Loss of connexin40 is associated with decreased endothelium-dependent relaxations and eNOS levels in the mouse aorta.

Alonso F, Boittin FX, Bény JL, Haefliger JA.

Am J Physiol Heart Circ Physiol. 2010 Nov;299(5):H1365-73. doi: 10.1152/ajpheart.00029.2010.


Accelerated endothelial dysfunction in mild prediabetic insulin resistance: the early role of reactive oxygen species.

Duncan ER, Walker SJ, Ezzat VA, Wheatcroft SB, Li JM, Shah AM, Kearney MT.

Am J Physiol Endocrinol Metab. 2007 Nov;293(5):E1311-9.


Dynamic association of nitric oxide downstream signaling molecules with endothelial caveolin-1 in rat aorta.

Linder AE, McCluskey LP, Cole KR 3rd, Lanning KM, Webb RC.

J Pharmacol Exp Ther. 2005 Jul;314(1):9-15.


Increased vascular contractility and oxidative stress in β₂-adrenoceptor knockout mice: the role of NADPH oxidase.

Davel AP, Ceravolo GS, Wenceslau CF, Carvalho MH, Brum PC, Rossoni LV.

J Vasc Res. 2012;49(4):342-52. doi: 10.1159/000337486.


Mechanisms for enhanced endothelium-derived hyperpolarizing factor-mediated responses in microvessels in mice.

Ohashi J, Sawada A, Nakajima S, Noda K, Takaki A, Shimokawa H.

Circ J. 2012;76(7):1768-79.


Deletion of inducible nitric oxide synthase decreases mesenteric vascular responsiveness in portal hypertensive mice.

Bexis S, Vandeputte C, McCormick PA, Docherty JR.

Eur J Pharmacol. 2004 Sep 24;499(3):325-33.


Mutation of the circadian clock gene Per2 alters vascular endothelial function.

Viswambharan H, Carvas JM, Antic V, Marecic A, Jud C, Zaugg CE, Ming XF, Montani JP, Albrecht U, Yang Z.

Circulation. 2007 Apr 24;115(16):2188-95.


An in vitro investigation of aorta and corpus cavernosum from eNOS and nNOS gene-deficient mice.

Nangle MR, Cotter MA, Cameron NE.

Pflugers Arch. 2004 May;448(2):139-45.

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