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Items: 1 to 20 of 103

1.

Piceatannol, a hydroxystilbene natural product, stabilizes HIF-1α protein by inhibiting HIF prolyl hydroxylase.

Yum S, Doh HJ, Hong S, Jeong S, Kim DD, Park M, Jung Y.

Eur J Pharmacol. 2013 Jan 15;699(1-3):124-31. doi: 10.1016/j.ejphar.2012.12.008. Epub 2012 Dec 19.

PMID:
23261967
2.

Lipophilic modification enhances anti-colitic properties of rosmarinic acid by potentiating its HIF-prolyl hydroxylases inhibitory activity.

Jeong S, Park H, Hong S, Yum S, Kim W, Jung Y.

Eur J Pharmacol. 2015 Jan 15;747:114-22. doi: 10.1016/j.ejphar.2014.11.030. Epub 2014 Dec 4.

PMID:
25483211
3.

N-(2-Mercaptopropionyl)-glycine, a diffusible antioxidant, activates HIF-1 by inhibiting HIF prolyl hydroxylase-2: implication in amelioration of rat colitis by the antioxidant.

Yum S, Park H, Hong S, Jeong S, Kim W, Jung Y.

Biochem Biophys Res Commun. 2014 Jan 17;443(3):1008-13. doi: 10.1016/j.bbrc.2013.12.081. Epub 2013 Dec 19.

PMID:
24361888
4.

HIF-prolyl hydroxylase is a potential molecular target for esculetin-mediated anti-colitic effects.

Yum S, Jeong S, Lee S, Kim W, Nam J, Jung Y.

Fitoterapia. 2015 Jun;103:55-62. doi: 10.1016/j.fitote.2015.03.013. Epub 2015 Mar 20.

PMID:
25797536
5.

Caffeic acid phenethyl ester is a potent inhibitor of HIF prolyl hydroxylase: structural analysis and pharmacological implication.

Choi D, Han J, Lee Y, Choi J, Han S, Hong S, Jeon H, Kim YM, Jung Y.

J Nutr Biochem. 2010 Sep;21(9):809-17. doi: 10.1016/j.jnutbio.2009.06.002. Epub 2009 Sep 8.

PMID:
19740641
6.

Rhapontigenin inhibited hypoxia inducible factor 1 alpha accumulation and angiogenesis in hypoxic PC-3 prostate cancer cells.

Jung DB, Lee HJ, Jeong SJ, Lee HJ, Lee EO, Kim YC, Ahn KS, Chen CY, Kim SH.

Biol Pharm Bull. 2011;34(6):850-5.

8.
9.

von Hippel-Lindau β-domain-luciferase fusion protein as a bioluminescent hydroxyproline sensor for a hypoxia-inducible factor prolyl hydroxylase assay.

Hong S, Yum S, Ha NC, Jung Y.

Anal Biochem. 2010 Dec 15;407(2):220-5. doi: 10.1016/j.ab.2010.08.013. Epub 2010 Aug 10.

PMID:
20705044
10.

Manganese (II) induces chemical hypoxia by inhibiting HIF-prolyl hydroxylase: implication in manganese-induced pulmonary inflammation.

Han J, Lee JS, Choi D, Lee Y, Hong S, Choi J, Han S, Ko Y, Kim JA, Kim YM, Jung Y.

Toxicol Appl Pharmacol. 2009 Mar 15;235(3):261-7. doi: 10.1016/j.taap.2009.01.003.

PMID:
19263519
11.

Src activates HIF-1α not through direct phosphorylation of HIF-1α specific prolyl-4 hydroxylase 2 but through activation of the NADPH oxidase/Rac pathway.

Lee HY, Lee T, Lee N, Yang EG, Lee C, Lee J, Moon EY, Ha J, Park H.

Carcinogenesis. 2011 May;32(5):703-12. doi: 10.1093/carcin/bgr034. Epub 2011 Feb 18.

PMID:
21335603
12.
13.

Nitric oxide donor, (+/-)-S-nitroso-N-acetylpenicillamine, stabilizes transactive hypoxia-inducible factor-1alpha by inhibiting von Hippel-Lindau recruitment and asparagine hydroxylation.

Park YK, Ahn DR, Oh M, Lee T, Yang EG, Son M, Park H.

Mol Pharmacol. 2008 Jul;74(1):236-45. doi: 10.1124/mol.108.045278. Epub 2008 Apr 21.

15.

Hypoxia-inducible factor-1alpha stabilization in nonhypoxic conditions: role of oxidation and intracellular ascorbate depletion.

Pagé EL, Chan DA, Giaccia AJ, Levine M, Richard DE.

Mol Biol Cell. 2008 Jan;19(1):86-94. Epub 2007 Oct 17.

16.

Nitric oxide reverses desferrioxamine- and hypoxia-evoked HIF-1alpha accumulation--implications for prolyl hydroxylase activity and iron.

Callapina M, Zhou J, Schnitzer S, Metzen E, Lohr C, Deitmer JW, Brüne B.

Exp Cell Res. 2005 May 15;306(1):274-84. Epub 2005 Mar 20.

PMID:
15878351
18.
19.
20.

A prolyl-hydroxylase inhibitor, ethyl-3,4-dihydroxybenzoate, induces haem oxygenase-1 expression in human cells through a mechanism independent of hypoxia-inducible factor-1alpha.

Li B, Takeda K, Yokoyama S, Shibahara S.

J Biochem. 2008 Nov;144(5):643-54. doi: 10.1093/jb/mvn115. Epub 2008 Sep 17.

PMID:
18799519

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