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Items: 1 to 20 of 77

1.

Co-chaperon DnaJC7/TPR2 enhances p53 stability and activity through blocking the complex formation between p53 and MDM2.

Kubo N, Wu D, Yoshihara Y, Sang M, Nakagawara A, Ozaki T.

Biochem Biophys Res Commun. 2013 Jan 18;430(3):1034-9. doi: 10.1016/j.bbrc.2012.11.121. Epub 2012 Dec 21.

PMID:
23261415
2.

Regulation of Mdm2 protein stability and the p53 response by NEDD4-1 E3 ligase.

Xu C, Fan CD, Wang X.

Oncogene. 2015 Jan 15;34(3):281-9. doi: 10.1038/onc.2013.557. Epub 2014 Jan 13.

PMID:
24413081
3.

DNAJB1 stabilizes MDM2 and contributes to cancer cell proliferation in a p53-dependent manner.

Qi M, Zhang J, Zeng W, Chen X.

Biochim Biophys Acta. 2014 Jan;1839(1):62-9. doi: 10.1016/j.bbagrm.2013.12.003. Epub 2013 Dec 19.

PMID:
24361594
4.

Identification of ribosomal protein S25 (RPS25)-MDM2-p53 regulatory feedback loop.

Zhang X, Wang W, Wang H, Wang MH, Xu W, Zhang R.

Oncogene. 2013 May 30;32(22):2782-91. doi: 10.1038/onc.2012.289. Epub 2012 Jul 9.

PMID:
22777350
5.

DNA damage-induced phosphorylation of MdmX at serine 367 activates p53 by targeting MdmX for Mdm2-dependent degradation.

Okamoto K, Kashima K, Pereg Y, Ishida M, Yamazaki S, Nota A, Teunisse A, Migliorini D, Kitabayashi I, Marine JC, Prives C, Shiloh Y, Jochemsen AG, Taya Y.

Mol Cell Biol. 2005 Nov;25(21):9608-20.

6.

Ribosomal protein S7 as a novel modulator of p53-MDM2 interaction: binding to MDM2, stabilization of p53 protein, and activation of p53 function.

Chen D, Zhang Z, Li M, Wang W, Li Y, Rayburn ER, Hill DL, Wang H, Zhang R.

Oncogene. 2007 Aug 2;26(35):5029-37. Epub 2007 Feb 19.

PMID:
17310983
7.

Transcriptional regulation of the mdm2 oncogene by p53 requires TRRAP acetyltransferase complexes.

Ard PG, Chatterjee C, Kunjibettu S, Adside LR, Gralinski LE, McMahon SB.

Mol Cell Biol. 2002 Aug;22(16):5650-61.

8.
9.

TAp73 alpha increases p53 tumor suppressor activity in thyroid cancer cells via the inhibition of Mdm2-mediated degradation.

Malaguarnera R, Vella V, Pandini G, Sanfilippo M, Pezzino V, Vigneri R, Frasca F.

Mol Cancer Res. 2008 Jan;6(1):64-77. doi: 10.1158/1541-7786.MCR-07-0005.

10.

L-GILZ binds p53 and MDM2 and suppresses tumor growth through p53 activation in human cancer cells.

Ayroldi E, Petrillo MG, Bastianelli A, Marchetti MC, Ronchetti S, Nocentini G, Ricciotti L, Cannarile L, Riccardi C.

Cell Death Differ. 2015 Jan;22(1):118-30. doi: 10.1038/cdd.2014.129. Epub 2014 Aug 29.

11.

Nuclear Localization Signal and p53 Binding Site in MAP/ERK Kinase Kinase 1 (MEKK1).

Chipps E, Protzman A, Muhi MZ, Ando S, Calvet JP, Islam MR.

J Cell Biochem. 2015 Dec;116(12):2903-14. doi: 10.1002/jcb.25238.

12.

CREB represses p53-dependent transactivation of MDM2 through the complex formation with p53 and contributes to p53-mediated apoptosis in response to glucose deprivation.

Okoshi R, Kubo N, Nakashima K, Shimozato O, Nakagawara A, Ozaki T.

Biochem Biophys Res Commun. 2011 Mar 4;406(1):79-84. doi: 10.1016/j.bbrc.2011.01.114. Epub 2011 Feb 3.

PMID:
21295542
13.

MdmX is required for p53 interaction with and full induction of the Mdm2 promoter after cellular stress.

Biderman L, Poyurovsky MV, Assia Y, Manley JL, Prives C.

Mol Cell Biol. 2012 Apr;32(7):1214-25. doi: 10.1128/MCB.06150-11. Epub 2012 Jan 30.

14.

p53 requires the stress sensor USF1 to direct appropriate cell fate decision.

Bouafia A, Corre S, Gilot D, Mouchet N, Prince S, Galibert MD.

PLoS Genet. 2014 May 15;10(5):e1004309. doi: 10.1371/journal.pgen.1004309. eCollection 2014.

15.

Elevated MDM2 boosts the apoptotic activity of p53-MDM2 binding inhibitors by facilitating MDMX degradation.

Xia M, Knezevic D, Tovar C, Huang B, Heimbrook DC, Vassilev LT.

Cell Cycle. 2008 Jun 1;7(11):1604-12. Epub 2008 Mar 17.

PMID:
18520179
16.

Proteasome activator PA28 gamma regulates p53 by enhancing its MDM2-mediated degradation.

Zhang Z, Zhang R.

EMBO J. 2008 Mar 19;27(6):852-64. doi: 10.1038/emboj.2008.25. Epub 2008 Feb 28.

17.

Knockdown of RNF2 induces apoptosis by regulating MDM2 and p53 stability.

Wen W, Peng C, Kim MO, Ho Jeong C, Zhu F, Yao K, Zykova T, Ma W, Carper A, Langfald A, Bode AM, Dong Z.

Oncogene. 2014 Jan 23;33(4):421-8. doi: 10.1038/onc.2012.605. Epub 2013 Jan 14.

18.

Protein phosphatase 1 nuclear targeting subunit is a hypoxia inducible gene: its role in post-translational modification of p53 and MDM2.

Lee SJ, Lim CJ, Min JK, Lee JK, Kim YM, Lee JY, Won MH, Kwon YG.

Cell Death Differ. 2007 Jun;14(6):1106-16. Epub 2007 Feb 23.

19.

SMAR1 forms a ternary complex with p53-MDM2 and negatively regulates p53-mediated transcription.

Pavithra L, Mukherjee S, Sreenath K, Kar S, Sakaguchi K, Roy S, Chattopadhyay S.

J Mol Biol. 2009 May 15;388(4):691-702. doi: 10.1016/j.jmb.2009.03.033. Epub 2009 Mar 19.

PMID:
19303885
20.

YY1 inhibits the activation of the p53 tumor suppressor in response to genotoxic stress.

Grönroos E, Terentiev AA, Punga T, Ericsson J.

Proc Natl Acad Sci U S A. 2004 Aug 17;101(33):12165-70. Epub 2004 Aug 4.

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