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Items: 1 to 20 of 105

1.

Inhibition of intracellular bacterial replication in fibroblasts is dependent on the perforin-like protein (perforin-2) encoded by macrophage-expressed gene 1.

McCormack R, de Armas LR, Shiratsuchi M, Ramos JE, Podack ER.

J Innate Immun. 2013;5(2):185-94. doi: 10.1159/000345249. Epub 2012 Dec 15.

2.

Macrophage-expressed perforins mpeg1 and mpeg1.2 have an anti-bacterial function in zebrafish.

Benard EL, Racz PI, Rougeot J, Nezhinsky AE, Verbeek FJ, Spaink HP, Meijer AH.

J Innate Immun. 2015;7(2):136-52. doi: 10.1159/000366103. Epub 2014 Sep 19.

PMID:
25247677
3.

Perforin-2 is essential for intracellular defense of parenchymal cells and phagocytes against pathogenic bacteria.

McCormack RM, de Armas LR, Shiratsuchi M, Fiorentino DG, Olsson ML, Lichtenheld MG, Morales A, Lyapichev K, Gonzalez LE, Strbo N, Sukumar N, Stojadinovic O, Plano GV, Munson GP, Tomic-Canic M, Kirsner RS, Russell DG, Podack ER.

Elife. 2015 Sep 24;4. pii: e06508. doi: 10.7554/eLife.06508.

4.

A perforin-like protein from a marine mollusk.

Mah SA, Moy GW, Swanson WJ, Vacquier VD.

Biochem Biophys Res Commun. 2004 Apr 2;316(2):468-75.

PMID:
15020241
5.

Perforin-2 Protects Host Cells and Mice by Restricting the Vacuole to Cytosol Transitioning of a Bacterial Pathogen.

McCormack R, Bahnan W, Shrestha N, Boucher J, Barreto M, Barrera CM, Dauer EA, Freitag NE, Khan WN, Podack ER, Schesser K.

Infect Immun. 2016 Mar 24;84(4):1083-91. doi: 10.1128/IAI.01434-15. Print 2016 Apr.

6.

Innate immune defense of the sponge Suberites domuncula against bacteria involves a MyD88-dependent signaling pathway. Induction of a perforin-like molecule.

Wiens M, Korzhev M, Krasko A, Thakur NL, Perović-Ottstadt S, Breter HJ, Ushijima H, Diehl-Seifert B, Müller IM, Müller WE.

J Biol Chem. 2005 Jul 29;280(30):27949-59. Epub 2005 May 27.

7.
8.

Perforin-2/Mpeg1 and other pore-forming proteins throughout evolution.

McCormack R, Podack ER.

J Leukoc Biol. 2015 Nov;98(5):761-8. doi: 10.1189/jlb.4MR1114-523RR. Epub 2015 Aug 25. Review.

10.

Virally infected hepatocytes are resistant to perforin-dependent CTL effector mechanisms.

Kafrouni MI, Brown GR, Thiele DL.

J Immunol. 2001 Aug 1;167(3):1566-74.

11.

Pore formers of the immune system.

Podack ER, Deyev V, Shiratsuchi M.

Adv Exp Med Biol. 2007;598:325-41. Review. No abstract available.

PMID:
17892222
12.

Enteric pathogens deploy cell cycle inhibiting factors to block the bactericidal activity of Perforin-2.

McCormack RM, Lyapichev K, Olsson ML, Podack ER, Munson GP.

Elife. 2015 Sep 29;4. pii: e06505. doi: 10.7554/eLife.06505.

13.

Use of the 5'-flanking region of the mouse perforin gene to express human Fc gamma receptor I in cytotoxic T lymphocytes.

Smyth MJ, Kershaw MH, Hulett MD, McKenzie IF, Trapani JA.

J Leukoc Biol. 1994 Apr;55(4):514-22.

PMID:
8145022
14.

Resistance of cytolytic lymphocytes to perforin-mediated killing. Induction of resistance correlates with increase in cytotoxicity.

Liu CC, Jiang S, Persechini PM, Zychlinsky A, Kaufmann Y, Young JD.

J Exp Med. 1989 Jun 1;169(6):2211-25.

15.

Complement membrane attack complex, perforin, and bacterial exotoxins induce in K562 cells calcium-dependent cross-protection from lysis.

Reiter Y, Ciobotariu A, Jones J, Morgan BP, Fishelson Z.

J Immunol. 1995 Aug 15;155(4):2203-10.

PMID:
7636268
16.

Homology of perforin to the ninth component of complement (C9).

Shinkai Y, Takio K, Okumura K.

Nature. 1988 Aug 11;334(6182):525-7.

PMID:
3261391
17.

Binding of perforin to membranes is sensitive to lipid spacing and not headgroup.

Antia R, Schlegel RA, Williamson P.

Immunol Lett. 1992 Apr;32(2):153-7.

PMID:
1612639
18.

A common fold mediates vertebrate defense and bacterial attack.

Rosado CJ, Buckle AM, Law RH, Butcher RE, Kan WT, Bird CH, Ung K, Browne KA, Baran K, Bashtannyk-Puhalovich TA, Faux NG, Wong W, Porter CJ, Pike RN, Ellisdon AM, Pearce MC, Bottomley SP, Emsley J, Smith AI, Rossjohn J, Hartland EL, Voskoboinik I, Trapani JA, Bird PI, Dunstone MA, Whisstock JC.

Science. 2007 Sep 14;317(5844):1548-51. Epub 2007 Aug 23.

19.
20.

Comparison of Fas(Apo-1/CD95)- and perforin-mediated cytotoxicity in primary T lymphocytes.

Lowin B, Mattman C, Hahne M, Tschopp J.

Int Immunol. 1996 Jan;8(1):57-63.

PMID:
8671589

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