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Items: 1 to 20 of 122

1.

The Ras-binding domain region of RGS14 regulates its functional interactions with heterotrimeric G proteins.

Zhao P, Nunn C, Ramineni S, Hepler JR, Chidiac P.

J Cell Biochem. 2013 Jun;114(6):1414-23. doi: 10.1002/jcb.24483.

2.

RGS14 is a bifunctional regulator of Galphai/o activity that exists in multiple populations in brain.

Hollinger S, Taylor JB, Goldman EH, Hepler JR.

J Neurochem. 2001 Dec;79(5):941-9.

3.

The RGS14 GoLoco domain discriminates among Galphai isoforms.

Mittal V, Linder ME.

J Biol Chem. 2004 Nov 5;279(45):46772-8. Epub 2004 Aug 26.

4.

The RGS (regulator of G-protein signalling) and GoLoco domains of RGS14 co-operate to regulate Gi-mediated signalling.

Traver S, Splingard A, Gaudriault G, De Gunzburg J.

Biochem J. 2004 May 1;379(Pt 3):627-32.

5.

Novel activity of RGS14 on Goalpha and Gialpha nucleotide binding and hydrolysis distinct from its RGS domain and GDI activity.

Hepler JR, Cladman W, Ramineni S, Hollinger S, Chidiac P.

Biochemistry. 2005 Apr 12;44(14):5495-502.

PMID:
15807543
6.

RGS12 and RGS14 GoLoco motifs are G alpha(i) interaction sites with guanine nucleotide dissociation inhibitor Activity.

Kimple RJ, De Vries L, Tronchère H, Behe CI, Morris RA, Gist Farquhar M, Siderovski DP.

J Biol Chem. 2001 Aug 3;276(31):29275-81. Epub 2001 May 31.

7.

Assembly and function of the regulator of G protein signaling 14 (RGS14)·H-Ras signaling complex in live cells are regulated by Gαi1 and Gαi-linked G protein-coupled receptors.

Vellano CP, Brown NE, Blumer JB, Hepler JR.

J Biol Chem. 2013 Feb 1;288(5):3620-31. doi: 10.1074/jbc.M112.440057. Epub 2012 Dec 17.

9.

Activation of the regulator of G protein signaling 14-Gαi1-GDP signaling complex is regulated by resistance to inhibitors of cholinesterase-8A.

Vellano CP, Shu FJ, Ramineni S, Yates CK, Tall GG, Hepler JR.

Biochemistry. 2011 Feb 8;50(5):752-62. doi: 10.1021/bi101910n. Epub 2011 Jan 11.

10.

G protein-coupled receptors and resistance to inhibitors of cholinesterase-8A (Ric-8A) both regulate the regulator of g protein signaling 14 RGS14·Gαi1 complex in live cells.

Vellano CP, Maher EM, Hepler JR, Blumer JB.

J Biol Chem. 2011 Nov 4;286(44):38659-69. doi: 10.1074/jbc.M111.274928. Epub 2011 Aug 31.

11.

Phosphorylation of RGS14 by protein kinase A potentiates its activity toward G alpha i.

Hollinger S, Ramineni S, Hepler JR.

Biochemistry. 2003 Jan 28;42(3):811-9.

PMID:
12534294
12.

RGS14 is a novel Rap effector that preferentially regulates the GTPase activity of galphao.

Traver S, Bidot C, Spassky N, Baltauss T, De Tand MF, Thomas JL, Zalc B, Janoueix-Lerosey I, Gunzburg JD.

Biochem J. 2000 Aug 15;350 Pt 1:19-29.

13.

The GAPs, GEFs, and GDIs of heterotrimeric G-protein alpha subunits.

Siderovski DP, Willard FS.

Int J Biol Sci. 2005;1(2):51-66. Epub 2005 Apr 1. Review.

14.

Integration of G protein α (Gα) signaling by the regulator of G protein signaling 14 (RGS14).

Brown NE, Goswami D, Branch MR, Ramineni S, Ortlund EA, Griffin PR, Hepler JR.

J Biol Chem. 2015 Apr 3;290(14):9037-49. doi: 10.1074/jbc.M114.634329. Epub 2015 Feb 9.

15.

Regulator of G-protein signalling and GoLoco proteins suppress TRPC4 channel function via acting at Gαi/o.

Jeon JP, Thakur DP, Tian JB, So I, Zhu MX.

Biochem J. 2016 May 15;473(10):1379-90. doi: 10.1042/BCJ20160214. Epub 2016 Mar 17.

PMID:
26987813
16.

RGS3 is a GTPase-activating protein for g(ialpha) and g(qalpha) and a potent inhibitor of signaling by GTPase-deficient forms of g(qalpha) and g(11alpha).

Scheschonka A, Dessauer CW, Sinnarajah S, Chidiac P, Shi CS, Kehrl JH.

Mol Pharmacol. 2000 Oct;58(4):719-28.

17.

RGS14, a GTPase-activating protein for Gialpha, attenuates Gialpha- and G13alpha-mediated signaling pathways.

Cho H, Kozasa T, Takekoshi K, De Gunzburg J, Kehrl JH.

Mol Pharmacol. 2000 Sep;58(3):569-76.

18.

RGS14 regulates the lifetime of Gα-GTP signaling but does not prolong Gβγ signaling following receptor activation in live cells.

Brown NE, Lambert NA, Hepler JR.

Pharmacol Res Perspect. 2016 Aug 18;4(5):e00249. eCollection 2016 Oct.

19.

Selective interactions between Gi alpha1 and Gi alpha3 and the GoLoco/GPR domain of RGS14 influence its dynamic subcellular localization.

Shu FJ, Ramineni S, Amyot W, Hepler JR.

Cell Signal. 2007 Jan;19(1):163-76. Epub 2006 Jul 25.

PMID:
16870394
20.

Regulation of RGS5 GAP activity by GPSM3.

Zhao P, Chidiac P.

Mol Cell Biochem. 2015 Jul;405(1-2):33-40. doi: 10.1007/s11010-015-2393-3. Epub 2015 Apr 5.

PMID:
25842189

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