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Items: 1 to 20 of 112

1.

Catalytic asymmetric Michael addition/cyclization of isothiocyanato oxindoles: highly efficient and versatile approach for the synthesis of 3,2'-pyrrolidinyl mono- and bi-spirooxindole frameworks.

Cao YM, Shen FF, Zhang FT, Wang R.

Chemistry. 2013 Jan 21;19(4):1184-8. doi: 10.1002/chem.201204114. Epub 2012 Dec 18. No abstract available.

PMID:
23255227
2.

Asymmetric Michael/cyclization cascade reaction of 3-isothiocyanato oxindoles and 3-nitroindoles with amino-thiocarbamate catalysts: enantioselective synthesis of polycyclic spirooxindoles.

Zhao JQ, Zhou MQ, Wu ZJ, Wang ZH, Yue DF, Xu XY, Zhang XM, Yuan WC.

Org Lett. 2015 May 1;17(9):2238-41. doi: 10.1021/acs.orglett.5b00850. Epub 2015 Apr 15.

PMID:
25875402
3.

Zn-Catalyzed Diastereo- and Enantioselective Cascade Reaction of 3-Isothiocyanato Oxindoles and 3-Nitroindoles: Stereocontrolled Syntheses of Polycyclic Spirooxindoles.

Zhao JQ, Wu ZJ, Zhou MQ, Xu XY, Zhang XM, Yuan WC.

Org Lett. 2015 Oct 16;17(20):5020-3. doi: 10.1021/acs.orglett.5b02489. Epub 2015 Sep 28.

PMID:
26412346
4.

Highly efficient enantioselective construction of bispirooxindoles containing three stereocenters through an organocatalytic cascade Michael-cyclization reaction.

Wu H, Zhang LL, Tian ZQ, Huang YD, Wang YM.

Chemistry. 2013 Jan 28;19(5):1747-53. doi: 10.1002/chem.201203221. Epub 2012 Dec 18.

PMID:
23255327
5.
6.

Catalytic Aldol-Cyclization Cascade of 3-Isothiocyanato Oxindoles with α-Ketophosphonates for the Enantioselective Synthesis of β-Amino-α-hydroxyphosphonates.

Kayal S, Mukherjee S.

Org Lett. 2015 Nov 6;17(21):5508-11. doi: 10.1021/acs.orglett.5b02929. Epub 2015 Oct 29.

PMID:
26512732
7.

Enantioselective cascade Michael addition/cyclization reactions of 3-nitro-2H-chromenes with 3-isothiocyanato oxindoles: efficient synthesis of functionalized polycyclic spirooxindoles.

Tan F, Lu LQ, Yang QQ, Guo W, Bian Q, Chen JR, Xiao WJ.

Chemistry. 2014 Mar 17;20(12):3415-20. doi: 10.1002/chem.201303583.

PMID:
24677230
8.

Assembly of spirooxindole derivatives containing four consecutive stereocenters via organocatalytic Michael-Henry cascade reactions.

Albertshofer K, Tan B, Barbas CF 3rd.

Org Lett. 2012 Apr 6;14(7):1834-7. doi: 10.1021/ol300441z. Epub 2012 Mar 22.

PMID:
22436132
9.

Organocatalytic tandem reaction to construct six-membered spirocyclic oxindoles with multiple chiral centres through a formal [2+2+2] annulation.

Jiang K, Jia ZJ, Chen S, Wu L, Chen YC.

Chemistry. 2010 Mar 1;16(9):2852-6. doi: 10.1002/chem.200903009.

PMID:
20112315
10.

Asymmetric synthesis of allenyl oxindoles and spirooxindoles by a catalytic enantioselective Saucy-Marbet Claisen rearrangement.

Cao T, Deitch J, Linton EC, Kozlowski MC.

Angew Chem Int Ed Engl. 2012 Mar 5;51(10):2448-51. doi: 10.1002/anie.201107417. Epub 2012 Jan 27. No abstract available.

11.

Catalytic asymmetric synthesis of spirooxindoles via addition of isothiocyanato oxindoles to aldehydes under dinuclear nickel Schiff base catalysis.

Kato S, Kanai M, Matsunaga S.

Chem Asian J. 2013 Aug;8(8):1768-71. doi: 10.1002/asia.201300251. Epub 2013 Apr 15. No abstract available.

PMID:
23589324
12.

Highly efficient and stereocontrolled construction of 3,3'-pyrrolidonyl spirooxindoles via organocatalytic domino Michael/cyclization reaction.

Liu XL, Han WY, Zhang XM, Yuan WC.

Org Lett. 2013 Mar 15;15(6):1246-9. doi: 10.1021/ol400183k. Epub 2013 Mar 1.

PMID:
23452297
13.

A Mannich/cyclization cascade process for the asymmetric synthesis of spirocyclic thioimidazolidineoxindoles.

Cai H, Zhou Y, Zhang D, Xu J, Liu H.

Chem Commun (Camb). 2014 Dec 7;50(94):14771-4. doi: 10.1039/c4cc06000h.

PMID:
25317757
14.

An asymmetric approach toward chiral multicyclic spirooxindoles from isothiocyanato oxindoles and unsaturated pyrazolones by a chiral tertiary amine thiourea catalyst.

Chen Q, Liang J, Wang S, Wang D, Wang R.

Chem Commun (Camb). 2013 Feb 25;49(16):1657-9. doi: 10.1039/c3cc38386e.

PMID:
23334197
15.

Catalytic [4+2] cyclization of α,β-unsaturated acyl chlorides with 3-alkylenyloxindoles: highly diastereo- and enantioselective synthesis of spirocarbocyclic oxindoles.

Shen LT, Jia WQ, Ye S.

Angew Chem Int Ed Engl. 2013 Jan 7;52(2):585-8. doi: 10.1002/anie.201207405. Epub 2012 Nov 13.

PMID:
23150385
16.

Tandem Michael addition-ring transformation reactions of 3-hydroxyoxindoles/3-aminooxindoles with olefinic azlactones: direct access to structurally diverse spirocyclic oxindoles.

Cui BD, Zuo J, Zhao JQ, Zhou MQ, Wu ZJ, Zhang XM, Yuan WC.

J Org Chem. 2014 Jun 6;79(11):5305-14. doi: 10.1021/jo500432c. Epub 2014 May 9.

PMID:
24785087
17.

Asymmetric synthesis of 3,3'-spirooxindoles fused with cyclobutanes through organocatalytic formal [2 + 2] cycloadditions under H-bond-directing dienamine activation.

Qi LW, Yang Y, Gui YY, Zhang Y, Chen F, Tian F, Peng L, Wang LX.

Org Lett. 2014 Dec 19;16(24):6436-9. doi: 10.1021/ol503266q. Epub 2014 Dec 10.

PMID:
25494171
18.

Asymmetric Catalytic Double Michael Additions for the Synthesis of Spirooxindoles.

Kang T, Zhao P, Yang J, Lin L, Feng X, Liu X.

Chemistry. 2018 Mar 12;24(15):3703-3706. doi: 10.1002/chem.201800043. Epub 2018 Feb 19.

PMID:
29369438
19.

Highly enantioselective one-pot synthesis of spirocyclopentaneoxindoles containing the oxime group by organocatalyzed Michael addition/ISOC/fragmentation sequence.

Li X, Li YM, Peng FZ, Wu ST, Li ZQ, Sun ZW, Zhang HB, Shao ZH.

Org Lett. 2011 Dec 2;13(23):6160-3. doi: 10.1021/ol2024955. Epub 2011 Nov 3.

PMID:
22050288
20.

One-pot tandem approach to spirocyclic oxindoles featuring adjacent spiro-stereocenters.

Liu YL, Wang X, Zhao YL, Zhu F, Zeng XP, Chen L, Wang CH, Zhao XL, Zhou J.

Angew Chem Int Ed Engl. 2013 Dec 16;52(51):13735-9. doi: 10.1002/anie.201307250. Epub 2013 Nov 7.

PMID:
24346948

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