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Tc9 cells, a new subset of CD8(+) T cells, support Th2-mediated airway inflammation.

Visekruna A, Ritter J, Scholz T, Campos L, Guralnik A, Poncette L, Raifer H, Hagner S, Garn H, Staudt V, Bopp T, Reuter S, Taube C, Loser K, Huber M.

Eur J Immunol. 2013 Mar;43(3):606-18. doi: 10.1002/eji.201242825. Epub 2013 Jan 31.


Expansion of regulatory CD8+ CD25+ T cells after neonatal alloimmunization.

Adams B, Dubois A, Delbauve S, Debock I, Lhommé F, Goldman M, Flamand V.

Clin Exp Immunol. 2011 Mar;163(3):354-61. doi: 10.1111/j.1365-2249.2010.04299.x. Epub 2010 Dec 22.


Regulation of Th2 responses and allergic inflammation through bystander activation of CD8+ T lymphocytes in early life.

Dubois A, Deruytter N, Adams B, Kanda A, Delbauve S, Fleury S, Torres D, François A, Pétein M, Goldman M, Dombrowicz D, Flamand V.

J Immunol. 2010 Jul 15;185(2):884-91. doi: 10.4049/jimmunol.0903287. Epub 2010 Jun 18.


Dendritic cells activated by an anti-inflammatory agent induce CD4(+) T helper type 2 responses without impairing CD8(+) memory and effector cytotoxic T-lymphocyte responses.

Wang Y, Da'Dara AA, Thomas PG, Harn DA.

Immunology. 2010 Mar;129(3):406-17. doi: 10.1111/j.1365-2567.2009.03193.x. Epub 2009 Nov 16.


CD4+ Th2 cells function alike effector Tr1 and Th1 cells through the deletion of a single cytokine IL-6 and IL-10 gene.

Ankathatti Munegowda M, Xu S, Freywald A, Xiang J.

Mol Immunol. 2012 Jun;51(2):143-9. doi: 10.1016/j.molimm.2012.02.120. Epub 2012 Mar 17.


STAT6 deletion converts the Th2 inflammatory pathology afflicting Lat(Y136F) mice into a lymphoproliferative disorder involving Th1 and CD8 effector T cells.

Archambaud C, Sansoni A, Mingueneau M, Devilard E, Delsol G, Malissen B, Malissen M.

J Immunol. 2009 Mar 1;182(5):2680-9. doi: 10.4049/jimmunol.0803257.


Interleukin 12 inhibits antigen-induced airway hyperresponsiveness, inflammation, and Th2 cytokine expression in mice.

Gavett SH, O'Hearn DJ, Li X, Huang SK, Finkelman FD, Wills-Karp M.

J Exp Med. 1995 Nov 1;182(5):1527-36.


Elf3 regulates allergic airway inflammation by controlling dendritic cell-driven T cell differentiation.

Kushwah R, Oliver JR, Wu J, Chang Z, Hu J.

J Immunol. 2011 Nov 1;187(9):4639-53. doi: 10.4049/jimmunol.1101967. Epub 2011 Sep 23.


Blocking IL-15 prevents the induction of allergen-specific T cells and allergic inflammation in vivo.

Rückert R, Brandt K, Braun A, Hoymann HG, Herz U, Budagian V, Dürkop H, Renz H, Bulfone-Paus S.

J Immunol. 2005 May 1;174(9):5507-15.


A Th17-like developmental process leads to CD8(+) Tc17 cells with reduced cytotoxic activity.

Huber M, Heink S, Grothe H, Guralnik A, Reinhard K, Elflein K, Hünig T, Mittrücker HW, Brüstle A, Kamradt T, Lohoff M.

Eur J Immunol. 2009 Jul;39(7):1716-25. doi: 10.1002/eji.200939412.


Allergen-specific CTL require perforin expression to suppress allergic airway inflammation.

Enomoto N, Hyde E, Ma JZ, Yang J, Forbes-Blom E, Delahunt B, Le Gros G, Ronchese F.

J Immunol. 2012 Feb 15;188(4):1734-41. doi: 10.4049/jimmunol.1102699. Epub 2012 Jan 16.


Inhibition of Th2 differentiation and GATA-3 expression by BCL-6.

Kusam S, Toney LM, Sato H, Dent AL.

J Immunol. 2003 Mar 1;170(5):2435-41.


Cutting edge: STAT6 signaling in eosinophils is necessary for development of allergic airway inflammation.

Stokes K, LaMarche NM, Islam N, Wood A, Huang W, August A.

J Immunol. 2015 Mar 15;194(6):2477-81. doi: 10.4049/jimmunol.1402096. Epub 2015 Feb 13.


Type 2 immune deviation has differential effects on alloreactive CD4+ and CD8+ T cells.

Matesic D, Valujskikh A, Pearlman E, Higgins AW, Gilliam AC, Heeger PS.

J Immunol. 1998 Nov 15;161(10):5236-44.


PAS-1, an Ascaris suum protein, modulates allergic airway inflammation via CD8+γδTCR+ and CD4+CD25+FoxP3+ T cells.

de Araújo CA, Perini A, Martins MA, Macedo MS, Macedo-Soares MF.

Scand J Immunol. 2010 Dec;72(6):491-503. doi: 10.1111/j.1365-3083.2010.02465.x.


STAT6 deficiency in a mouse model of allergen-induced airways inflammation abolishes eosinophilia but induces infiltration of CD8+ T cells.

Miyata S, Matsuyama T, Kodama T, Nishioka Y, Kuribayashi K, Takeda K, Akira S, Sugita M.

Clin Exp Allergy. 1999 Jan;29(1):114-23.


Cyclooxygenase inhibition during allergic sensitization increases STAT6-independent primary and memory Th2 responses.

Zhou W, Newcomb DC, Moore ML, Goleniewska K, O'Neal JF, Peebles RS Jr.

J Immunol. 2008 Oct 15;181(8):5360-7.

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