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Items: 1 to 20 of 99

1.

Inhibitory effects of a bazedoxifene/conjugated equine estrogen combination on human breast cancer cells in vitro.

Song Y, Santen RJ, Wang JP, Yue W.

Endocrinology. 2013 Feb;154(2):656-65. doi: 10.1210/en.2012-2038. Epub 2012 Dec 19.

PMID:
23254198
2.

Effects of the conjugated equine estrogen/bazedoxifene tissue-selective estrogen complex (TSEC) on mammary gland and breast cancer in mice.

Song Y, Santen RJ, Wang JP, Yue W.

Endocrinology. 2012 Dec;153(12):5706-15. doi: 10.1210/en.2012-1583. Epub 2012 Oct 15.

3.

Tissue-selective estrogen complexes for postmenopausal women.

Mirkin S, Komm BS.

Maturitas. 2013 Nov;76(3):213-20. doi: 10.1016/j.maturitas.2013.06.003. Epub 2013 Jul 11. Review.

PMID:
23849704
4.

Preclinical breast effects of a tissue selective estrogen complex (TSEC) including conjugated estrogen with bazedoxifene.

Santen RJ, Song Y, Wang JP, Yue W.

J Steroid Biochem Mol Biol. 2017 Jun;170:61-64. doi: 10.1016/j.jsbmb.2016.05.008. Epub 2016 May 9. Review.

PMID:
27174719
5.

Gene expression profiling studies of three SERMs and their conjugated estrogen combinations in human breast cancer cells: insights into the unique antagonistic effects of bazedoxifene on conjugated estrogens.

Chang KC, Wang Y, Bodine PV, Nagpal S, Komm BS.

J Steroid Biochem Mol Biol. 2010 Jan;118(1-2):117-24. doi: 10.1016/j.jsbmb.2009.11.003. Epub 2009 Nov 13.

PMID:
19914376
6.

Differential utilization of nuclear and extranuclear receptor signaling pathways in the actions of estrogens, SERMs, and a tissue-selective estrogen complex (TSEC).

Madak-Erdogan Z, Gong P, Katzenellenbogen BS.

J Steroid Biochem Mol Biol. 2016 Apr;158:198-206. doi: 10.1016/j.jsbmb.2015.12.008. Epub 2015 Dec 12.

PMID:
26689478
7.

Development of conjugated estrogens/bazedoxifene, the first tissue selective estrogen complex (TSEC) for management of menopausal hot flashes and postmenopausal bone loss.

Komm BS, Mirkin S, Jenkins SN.

Steroids. 2014 Nov;90:71-81. doi: 10.1016/j.steroids.2014.06.004. Epub 2014 Jun 11. Review.

PMID:
24929044
8.

Treatment with bazedoxifene and conjugated estrogens results in regression of endometriosis in a murine model.

Naqvi H, Sakr S, Presti T, Krikun G, Komm B, Taylor HS.

Biol Reprod. 2014 Jun;90(6):121. doi: 10.1095/biolreprod.113.114165. Epub 2014 Apr 16.

9.

Differential biochemical and cellular actions of Premarin estrogens: distinct pharmacology of bazedoxifene-conjugated estrogens combination.

Berrodin TJ, Chang KC, Komm BS, Freedman LP, Nagpal S.

Mol Endocrinol. 2009 Jan;23(1):74-85. doi: 10.1210/me.2008-0366. Epub 2008 Nov 26.

10.

Selective estrogen modulators in menopause.

Gambacciani M.

Minerva Ginecol. 2013 Dec;65(6):621-30.

PMID:
24346250
11.

Effects of various selective estrogen receptor modulators with or without conjugated estrogens on mouse mammary gland.

Peano BJ, Crabtree JS, Komm BS, Winneker RC, Harris HA.

Endocrinology. 2009 Apr;150(4):1897-903. doi: 10.1210/en.2008-1210. Epub 2008 Nov 20.

PMID:
19022889
12.

Selective estrogen receptor modulators and the combination therapy conjugated estrogens/bazedoxifene: A review of effects on the breast.

Pickar JH, Komm BS.

Post Reprod Health. 2015 Sep;21(3):112-21. doi: 10.1177/2053369115599090. Epub 2015 Aug 19. Review.

PMID:
26289836
13.

Effects of menopausal hormonal therapy on occult breast tumors.

Santen RJ, Song Y, Yue W, Wang JP, Heitjan DF.

J Steroid Biochem Mol Biol. 2013 Sep;137:150-6. doi: 10.1016/j.jsbmb.2013.05.008. Epub 2013 Jun 7. Review.

PMID:
23748149
14.

Bazedoxifene and Conjugated Equine Estrogen: A Combination Product for the Management of Vasomotor Symptoms and Osteoporosis Prevention Associated with Menopause.

Umland EM, Karel L, Santoro N.

Pharmacotherapy. 2016 May;36(5):548-61. doi: 10.1002/phar.1749. Epub 2016 May 11. Review.

PMID:
27027527
15.

Breast-related effects of selective estrogen receptor modulators and tissue-selective estrogen complexes.

Smith CL, Santen RJ, Komm B, Mirkin S.

Breast Cancer Res. 2014 Jun 18;16(3):212. doi: 10.1186/bcr3677. Review.

16.

Treating menopausal symptoms with a tissue-selective estrogen complex.

Levine JP.

Gend Med. 2011 Apr;8(2):57-68. doi: 10.1016/j.genm.2011.03.008. Review.

PMID:
21536225
17.

Endometrial effects of a tissue selective estrogen complex containing bazedoxifene/conjugated estrogens as a menopausal therapy.

Pickar JH, Yeh IT, Bachmann G, Speroff L.

Fertil Steril. 2009 Sep;92(3):1018-24. doi: 10.1016/j.fertnstert.2009.05.094. Epub 2009 Jul 26.

PMID:
19635613
18.

Perspective on prescribing conjugated estrogens/bazedoxifene for estrogen-deficiency symptoms of menopause: a practical guide.

Palacios S, Currie H, Mikkola TS, Dragon E.

Maturitas. 2015 Apr;80(4):435-40. doi: 10.1016/j.maturitas.2015.01.003. Epub 2015 Jan 24. Review.

PMID:
25684082
19.

Evaluation of the efficacy and safety of bazedoxifene/conjugated estrogens for secondary outcomes including vasomotor symptoms in postmenopausal women by years since menopause in the Selective estrogens, Menopause and Response to Therapy (SMART) trials.

Pinkerton JV, Abraham L, Bushmakin AG, Cappelleri JC, Racketa J, Shi H, Chines AA, Mirkin S.

J Womens Health (Larchmt). 2014 Jan;23(1):18-28. doi: 10.1089/jwh.2013.4392. Epub 2013 Nov 9.

PMID:
24206058
20.

Evaluation of bazedoxifene/conjugated estrogens for the treatment of menopausal symptoms and effects on metabolic parameters and overall safety profile.

Lobo RA, Pinkerton JV, Gass ML, Dorin MH, Ronkin S, Pickar JH, Constantine G.

Fertil Steril. 2009 Sep;92(3):1025-38. doi: 10.1016/j.fertnstert.2009.03.113. Epub 2009 Jul 26.

PMID:
19635615

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