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Items: 1 to 20 of 235

1.

Edaravone protects HT22 neurons from H2O2-induced apoptosis by inhibiting the MAPK signaling pathway.

Zhao ZY, Luan P, Huang SX, Xiao SH, Zhao J, Zhang B, Gu BB, Pi RB, Liu J.

CNS Neurosci Ther. 2013 Mar;19(3):163-9. doi: 10.1111/cns.12044. Epub 2012 Dec 18.

PMID:
23253171
2.

[The study of the protective effect and its mechanism of Edaravone to neurons with hydrogen peroxide stimulated].

Long H, Zhang N, Fan J, Li QQ, Li YM, Tang J, Cheng G, Yin GY, Cai WH.

Zhonghua Wai Ke Za Zhi. 2013 Mar;51(3):266-71. Chinese.

PMID:
23859332
3.

Nitric oxide-induced apoptosis in cultured rat astrocytes: protection by edaravone, a radical scavenger.

Kawasaki T, Kitao T, Nakagawa K, Fujisaki H, Takegawa Y, Koda K, Ago Y, Baba A, Matsuda T.

Glia. 2007 Oct;55(13):1325-33.

PMID:
17626263
4.

Edaravone protects cortical neurons from apoptosis by inhibiting the translocation of BAX and Increasing the interaction between 14-3-3 and p-BAD.

Fan J, Zhang N, Yin G, Zhang Z, Cheng G, Qian W, Long H, Cai W.

Int J Neurosci. 2012 Nov;122(11):665-74. doi: 10.3109/00207454.2012.707714. Epub 2012 Aug 21.

PMID:
22757651
5.

Neurotropin® alleviates hippocampal neuron damage through a HIF-1α/MAPK pathway.

Fang WL, Zhao DQ, Wang F, Li M, Fan SN, Liao W, Zheng YQ, Liao SW, Xiao SH, Luan P, Liu J.

CNS Neurosci Ther. 2017 May;23(5):428-437. doi: 10.1111/cns.12689. Epub 2017 Mar 7.

PMID:
28271615
6.

Edaravone leads to proteome changes indicative of neuronal cell protection in response to oxidative stress.

Jami MS, Salehi-Najafabadi Z, Ahmadinejad F, Hoedt E, Chaleshtori MH, Ghatrehsamani M, Neubert TA, Larsen JP, Møller SG.

Neurochem Int. 2015 Nov;90:134-41. doi: 10.1016/j.neuint.2015.07.024. Epub 2015 Jul 29.

7.

Hydrogen peroxide-induced neuronal apoptosis is associated with inhibition of protein phosphatase 2A and 5, leading to activation of MAPK pathway.

Chen L, Liu L, Yin J, Luo Y, Huang S.

Int J Biochem Cell Biol. 2009 Jun;41(6):1284-95. doi: 10.1016/j.biocel.2008.10.029. Epub 2008 Nov 6.

PMID:
19038359
8.

Protective effect of edaravone against hypoxia-reoxygenation injury in rabbit cardiomyocytes.

Yamawaki M, Sasaki N, Shimoyama M, Miake J, Ogino K, Igawa O, Tajima F, Shigemasa C, Hisatome I.

Br J Pharmacol. 2004 Jun;142(3):618-26. Epub 2004 May 17.

9.

Edaravone protects against MPP+ -induced cytotoxicity in rat primary cultured astrocytes via inhibition of mitochondrial apoptotic pathway.

Chen H, Wang S, Ding JH, Hu G.

J Neurochem. 2008 Sep;106(6):2345-52. doi: 10.1111/j.1471-4159.2008.05573.x. Epub 2008 Jul 15.

10.

Edaravone, a free radical scavenger, protects against retinal damage in vitro and in vivo.

Inokuchi Y, Imai S, Nakajima Y, Shimazawa M, Aihara M, Araie M, Hara H.

J Pharmacol Exp Ther. 2009 May;329(2):687-98. doi: 10.1124/jpet.108.148676. Epub 2009 Feb 6.

11.

Midazolam anesthesia protects neuronal cells from oxidative stress-induced death via activation of the JNK-ERK pathway.

Liu JY, Guo F, Wu HL, Wang Y, Liu JS.

Mol Med Rep. 2017 Jan;15(1):169-179. doi: 10.3892/mmr.2016.6031. Epub 2016 Dec 12.

12.

Kaempferol attenuates the glutamate-induced oxidative stress in mouse-derived hippocampal neuronal HT22 cells.

Yang EJ, Kim GS, Jun M, Song KS.

Food Funct. 2014 Jul 25;5(7):1395-402. doi: 10.1039/c4fo00068d.

PMID:
24770605
13.

The free radical scavenger edaravone rescues rats from cerebral infarction by attenuating the release of high-mobility group box-1 in neuronal cells.

Kikuchi K, Kawahara K, Tancharoen S, Matsuda F, Morimoto Y, Ito T, Biswas KK, Takenouchi K, Miura N, Oyama Y, Nawa Y, Arimura N, Iwata M, Tajima Y, Kuramoto T, Nakayama K, Shigemori M, Yoshida Y, Hashiguchi T, Maruyama I.

J Pharmacol Exp Ther. 2009 Jun;329(3):865-74. doi: 10.1124/jpet.108.149484. Epub 2009 Mar 17.

14.

The radical scavenger edaravone prevents oxidative neurotoxicity induced by peroxynitrite and activated microglia.

Banno M, Mizuno T, Kato H, Zhang G, Kawanokuchi J, Wang J, Kuno R, Jin S, Takeuchi H, Suzumura A.

Neuropharmacology. 2005 Feb;48(2):283-90. Epub 2004 Dec 24.

PMID:
15695167
16.

Jatrorrhizine Protects Against Okadaic Acid Induced Oxidative Toxicity Through Inhibiting the Mitogen-Activated Protein Kinases Pathways in HT22 Hippocampal Neurons.

Jiang W, Duan WB, Li S, Shen XY, Zhou Y, Luo T, He F, Xu J, Wang HQ.

CNS Neurol Disord Drug Targets. 2015;14(10):1334-42.

PMID:
26295822
17.

Puerarin protects differentiated PC12 cells from H₂O₂-induced apoptosis through the PI3K/Akt signalling pathway.

Zhang Q, Huang WD, Lv XY, Yang YM.

Cell Biol Int. 2012 May 1;36(5):419-26. doi: 10.1042/CBI20100900.

PMID:
22126839
18.

Protective effects of the free radical scavenger edaravone against glutamate neurotoxicity in nearly pure neuronal culture.

Hisano K, Watanabe M, Morimoto Y.

J Anesth. 2009;23(3):363-9. doi: 10.1007/s00540-009-0766-z. Epub 2009 Aug 14.

PMID:
19685116
19.

Protection by genistein on cortical neurons against oxidative stress injury via inhibition of NF-kappaB, JNK and ERK signaling pathway.

Qian Y, Cao L, Guan T, Chen L, Xin H, Li Y, Zheng R, Yu D.

Pharm Biol. 2015 Aug;53(8):1124-32. doi: 10.3109/13880209.2014.962057. Epub 2015 Feb 26.

PMID:
25715966
20.

Superoxide anions and hydrogen peroxide induce hepatocyte death by different mechanisms: involvement of JNK and ERK MAP kinases.

Conde de la Rosa L, Schoemaker MH, Vrenken TE, Buist-Homan M, Havinga R, Jansen PL, Moshage H.

J Hepatol. 2006 May;44(5):918-29. Epub 2005 Sep 12.

PMID:
16310883

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