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Items: 1 to 20 of 99

1.

Molecular characterization of farnesyl pyrophosphate synthase from Bacopa monniera by comparative modeling and docking studies.

Vishwakarma RK, Patel KA, Sonawane P, Singh S, Ruby, Kumari U, Agrawal DC, Khan BM.

Bioinformation. 2012;8(22):1075-81. doi: 10.6026/97320630081075.

2.

Functional characterization of the Xanthophyllomyces dendrorhous farnesyl pyrophosphate synthase and geranylgeranyl pyrophosphate synthase encoding genes that are involved in the synthesis of isoprenoid precursors.

Alcaíno J, Romero I, Niklitschek M, Sepúlveda D, Rojas MC, Baeza M, Cifuentes V.

PLoS One. 2014 May 5;9(5):e96626. doi: 10.1371/journal.pone.0096626.

3.

Farnesyl pyrophosphate synthase: a key enzyme in isoprenoid biosynthetic pathway and potential molecular target for drug development.

Dhar MK, Koul A, Kaul S.

N Biotechnol. 2013 Jan 25;30(2):114-23. doi: 10.1016/j.nbt.2012.07.001. Review.

PMID:
22842101
4.
5.

Molecular regulation of santalol biosynthesis in Santalum album L.

Rani A, Ravikumar P, Reddy MD, Kush A.

Gene. 2013 Sep 25;527(2):642-8. doi: 10.1016/j.gene.2013.06.080.

PMID:
23860319
6.

Farnesyl diphosphate synthase assay.

Arró M, Manzano D, Ferrer A.

Methods Mol Biol. 2014;1153:41-53. doi: 10.1007/978-1-4939-0606-2_4.

PMID:
24777789
7.

Structural analysis of farnesyl pyrophosphate synthase from parasitic protozoa, a potential chemotherapeutic target.

Srivastava A, Mukherjee P, Desai PV, Avery MA, Tekwani BL.

Infect Disord Drug Targets. 2008 Mar;8(1):16-30. Review.

PMID:
18473904
8.

Farnesyl pyrophosphate synthase is the molecular target of nitrogen-containing bisphosphonates.

van Beek E, Pieterman E, Cohen L, Löwik C, Papapoulos S.

Biochem Biophys Res Commun. 1999 Oct 14;264(1):108-11.

PMID:
10527849
10.

The molecular mechanism of nitrogen-containing bisphosphonates as antiosteoporosis drugs.

Kavanagh KL, Guo K, Dunford JE, Wu X, Knapp S, Ebetino FH, Rogers MJ, Russell RG, Oppermann U.

Proc Natl Acad Sci U S A. 2006 May 16;103(20):7829-34.

11.

Investigation of the catalytic mechanism of farnesyl pyrophosphate synthase by computer simulation.

Sanchez VM, Crespo A, Gutkind JS, Turjanski AG.

J Phys Chem B. 2006 Sep 14;110(36):18052-7.

PMID:
16956297
12.

Approaches for Designing new Potent Inhibitors of Farnesyl Pyrophosphate Synthase.

Rodriguez JB, Falcone BN, Szajnman SH.

Expert Opin Drug Discov. 2016;11(3):307-20. doi: 10.1517/17460441.2016.1143814. Review.

PMID:
26781029
13.

Disruption of insect isoprenoid biosynthesis with pyridinium bisphosphonates.

Sen SE, Wood L, Jacob R, Xhambazi A, Pease B, Jones A, Horsfield T, Lin A, Cusson M.

Insect Biochem Mol Biol. 2015 Aug;63:113-23. doi: 10.1016/j.ibmb.2015.05.006.

PMID:
26073627
14.

Modeling studies with Helicobacter pylori octaprenyl pyrophosphate synthase reveal the enzymatic mechanism of trans-prenyltransferases.

Zhang J, Zhang X, Zhang R, Wu C, Guo Y, Mao X, Guo G, Zhang Y, Wang DC, Li D, Zou Q.

Int J Biochem Cell Biol. 2012 Dec;44(12):2116-23. doi: 10.1016/j.biocel.2012.09.002.

PMID:
22982238
15.

Bisphosphonates: the first 40 years.

Russell RG.

Bone. 2011 Jul;49(1):2-19. doi: 10.1016/j.bone.2011.04.022. Review.

PMID:
21555003
16.

Targeting isoprenoid biosynthesis for drug discovery: bench to bedside.

Oldfield E.

Acc Chem Res. 2010 Sep 21;43(9):1216-26. doi: 10.1021/ar100026v.

17.

In silico study of binding motifs in squalene synthase enzyme of secondary metabolic pathway of solanaceae [corrected].

Sanchita, Singh G, Sharma A.

Mol Biol Rep. 2014 Nov;41(11):7201-8. doi: 10.1007/s11033-014-3603-x. Erratum in: Mol Biol Rep. 2014 Dec;41(12):8333.

PMID:
25106523
18.
19.

Structure of human farnesyl pyrophosphate synthase in complex with an aminopyridine bisphosphonate and two molecules of inorganic phosphate.

Park J, Lin YS, Tsantrizos YS, Berghuis AM.

Acta Crystallogr F Struct Biol Commun. 2014 Mar;70(Pt 3):299-304. doi: 10.1107/S2053230X14002106.

20.

A corpora allata farnesyl diphosphate synthase in mosquitoes displaying a metal ion dependent substrate specificity.

Rivera-Perez C, Nyati P, Noriega FG.

Insect Biochem Mol Biol. 2015 Sep;64:44-50. doi: 10.1016/j.ibmb.2015.07.010.

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