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Items: 1 to 20 of 143

1.

Myeloid cell HIF-1α regulates asthma airway resistance and eosinophil function.

Crotty Alexander LE, Akong-Moore K, Feldstein S, Johansson P, Nguyen A, McEachern EK, Nicatia S, Cowburn AS, Olson J, Cho JY, Isaacs H Jr, Johnson RS, Broide DH, Nizet V.

J Mol Med (Berl). 2013 May;91(5):637-44. doi: 10.1007/s00109-012-0986-9. Epub 2012 Dec 19.

2.

Hypoxia-inducible factor-1α inhibition modulates airway hyperresponsiveness and nitric oxide levels in a BALB/c mouse model of asthma.

Dewitz C, McEachern E, Shin S, Akong K, Nagle DG, Broide DH, Akuthota P, Crotty Alexander LE.

Clin Immunol. 2017 Mar;176:94-99. doi: 10.1016/j.clim.2017.01.002. Epub 2017 Jan 14.

PMID:
28093362
3.

Neonatal epithelial hypoxia inducible factor-1α expression regulates the response of the lung to experimental asthma.

Greenwood KK, Proper SP, Saini Y, Bramble LA, Jackson-Humbles DN, Wagner JG, Harkema JR, LaPres JJ.

Am J Physiol Lung Cell Mol Physiol. 2012 Mar 1;302(5):L455-62. doi: 10.1152/ajplung.00193.2011. Epub 2011 Dec 16.

4.

Requirement of apoptosis-inducing kinase 1 for the induction of bronchial asthma following stimulation with ovalbumin.

Takada E, Furuhata M, Nakae S, Ichijo H, Sudo K, Mizuguchi J.

Int Arch Allergy Immunol. 2013;162(2):104-14. doi: 10.1159/000353240. Epub 2013 Jul 31.

5.

Potent ameliorating effect of Hypoxia-inducible factor 1α (HIF-1α) antagonist YC-1 on combined allergic rhinitis and asthma syndrome (CARAS) in Rats.

Wang X, Liu C, Wu L, Zhu S.

Eur J Pharmacol. 2016 Oct 5;788:343-350. doi: 10.1016/j.ejphar.2016.07.040. Epub 2016 Aug 4.

PMID:
27498367
6.

α-Galactosylceramide-induced airway eosinophilia is mediated through the activation of NKT cells.

Chuang YH, Wang TC, Jen HY, Yu AL, Chiang BL.

J Immunol. 2011 Apr 15;186(8):4687-92. doi: 10.4049/jimmunol.1003659. Epub 2011 Mar 7.

7.

HIF-1α inhibition ameliorates an allergic airway disease via VEGF suppression in bronchial epithelium.

Kim SR, Lee KS, Park HS, Park SJ, Min KH, Moon H, Puri KD, Lee YC.

Eur J Immunol. 2010 Oct;40(10):2858-69. doi: 10.1002/eji.200939948.

8.

AcCystatin, an immunoregulatory molecule from Angiostrongylus cantonensis, ameliorates the asthmatic response in an aluminium hydroxide/ovalbumin-induced rat model of asthma.

Ji P, Hu H, Yang X, Wei X, Zhu C, Liu J, Feng Y, Yang F, Okanurak K, Li N, Zeng X, Zheng H, Wu Z, Lv Z.

Parasitol Res. 2015 Feb;114(2):613-24. doi: 10.1007/s00436-014-4223-z. Epub 2014 Nov 18.

PMID:
25399816
9.

Role of signal transducer and activator of transcription 1 in murine allergen-induced airway remodeling and exacerbation by carbon nanotubes.

Thompson EA, Sayers BC, Glista-Baker EE, Shipkowski KA, Ihrie MD, Duke KS, Taylor AJ, Bonner JC.

Am J Respir Cell Mol Biol. 2015 Nov;53(5):625-36. doi: 10.1165/rcmb.2014-0221OC.

10.

p110γ/δ Double-Deficiency Induces Eosinophilia and IgE Production but Protects from OVA-Induced Airway Inflammation.

Mothes B, Bucher K, Ammon-Treiber S, Schwab M, Piekorz RP, Hirsch E, Nürnberg B, Beer-Hammer S.

PLoS One. 2016 Jul 21;11(7):e0159310. doi: 10.1371/journal.pone.0159310. eCollection 2016. Erratum in: PLoS One. 2016;11(9):e0163577.

11.

Grape seed proanthocyanidin extract attenuates allergic inflammation in murine models of asthma.

Lee T, Kwon HS, Bang BR, Lee YS, Park MY, Moon KA, Kim TB, Lee KY, Moon HB, Cho YS.

J Clin Immunol. 2012 Dec;32(6):1292-304. doi: 10.1007/s10875-012-9742-8. Epub 2012 Jul 27.

PMID:
22836658
12.

Exaggerated IL-17 response to epicutaneous sensitization mediates airway inflammation in the absence of IL-4 and IL-13.

He R, Kim HY, Yoon J, Oyoshi MK, MacGinnitie A, Goya S, Freyschmidt EJ, Bryce P, McKenzie AN, Umetsu DT, Oettgen HC, Geha RS.

J Allergy Clin Immunol. 2009 Oct;124(4):761-70.e1. doi: 10.1016/j.jaci.2009.07.040.

13.

Enhanced interferon-gamma gene expression in T Cells and reduced ovalbumin-dependent lung eosinophilia in hypoxia-inducible factor-1-alpha-deficient mice.

Guo J, Lu W, Shimoda LA, Semenza GL, Georas SN.

Int Arch Allergy Immunol. 2009;149(2):98-102. doi: 10.1159/000189191. Epub 2009 Jan 6.

14.

Lipopolysaccharides promote a shift from Th2-derived airway eosinophilic inflammation to Th17-derived neutrophilic inflammation in an ovalbumin-sensitized murine asthma model.

Zhao S, Jiang Y, Yang X, Guo D, Wang Y, Wang J, Wang R, Wang C.

J Asthma. 2017 Jun;54(5):447-455. doi: 10.1080/02770903.2016.1223687. Epub 2016 Sep 2.

PMID:
27589490
15.

TNF-α enhance Th2 and Th17 immune responses regulating by IL23 during sensitization in asthma model.

Lee HS, Park HW, Song WJ, Jeon EY, Bang B, Shim EJ, Moon HG, Kim YK, Kang HR, Min KU, Cho SH.

Cytokine. 2016 Mar;79:23-30. doi: 10.1016/j.cyto.2015.12.001. Epub 2015 Dec 21.

PMID:
26717421
16.

AMPK activation reduces vascular permeability and airway inflammation by regulating HIF/VEGFA pathway in a murine model of toluene diisocyanate-induced asthma.

Park SJ, Lee KS, Kim SR, Chae HJ, Yoo WH, Kim DI, Jeon MS, Lee YC.

Inflamm Res. 2012 Oct;61(10):1069-83. doi: 10.1007/s00011-012-0499-6. Epub 2012 Jun 13.

PMID:
22692279
17.

A murine IL-4 receptor antagonist that inhibits IL-4- and IL-13-induced responses prevents antigen-induced airway eosinophilia and airway hyperresponsiveness.

Tomkinson A, Duez C, Cieslewicz G, Pratt JC, Joetham A, Shanafelt MC, Gundel R, Gelfand EW.

J Immunol. 2001 May 1;166(9):5792-800.

18.

A role for cysteinyl leukotrienes in airway remodeling in a mouse asthma model.

Henderson WR Jr, Tang LO, Chu SJ, Tsao SM, Chiang GK, Jones F, Jonas M, Pae C, Wang H, Chi EY.

Am J Respir Crit Care Med. 2002 Jan 1;165(1):108-16.

PMID:
11779739
19.

Hypoxia inducible factor promotes murine allergic airway inflammation and is increased in asthma and rhinitis.

Huerta-Yepez S, Baay-Guzman GJ, Bebenek IG, Hernandez-Pando R, Vega MI, Chi L, Riedl M, Diaz-Sanchez D, Kleerup E, Tashkin DP, Gonzalez FJ, Bonavida B, Zeidler M, Hankinson O.

Allergy. 2011 Jul;66(7):909-18. doi: 10.1111/j.1398-9995.2011.02594.x. Epub 2011 Apr 26.

20.

A synthetic compound, 4-acetyl-3-methyl-6-(3,4,5-trimethoxyphenyl)pyrano[3,4-c]pyran-1,8-dione, ameliorates ovalbumin-induced asthma.

Chung HS, Kim Y, Oh SJ, Kim H, Choi SI, Zhang Y, Jeong JH, Bae H.

Bioorg Med Chem. 2013 Nov 1;21(21):6359-65. doi: 10.1016/j.bmc.2013.08.045. Epub 2013 Sep 3.

PMID:
24054491

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