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Items: 1 to 20 of 101

1.

pH (low) insertion peptide (pHLIP) targets ischemic myocardium.

Sosunov EA, Anyukhovsky EP, Sosunov AA, Moshnikova A, Wijesinghe D, Engelman DM, Reshetnyak YK, Andreev OA.

Proc Natl Acad Sci U S A. 2013 Jan 2;110(1):82-6. doi: 10.1073/pnas.1220038110. Epub 2012 Dec 17.

2.

Targeting breast tumors with pH (low) insertion peptides.

Adochite RC, Moshnikova A, Carlin SD, Guerrieri RA, Andreev OA, Lewis JS, Reshetnyak YK.

Mol Pharm. 2014 Aug 4;11(8):2896-905. doi: 10.1021/mp5002526. Epub 2014 Jul 8.

3.

pHLIP peptide targets nanogold particles to tumors.

Yao L, Daniels J, Moshnikova A, Kuznetsov S, Ahmed A, Engelman DM, Reshetnyak YK, Andreev OA.

Proc Natl Acad Sci U S A. 2013 Jan 8;110(2):465-70. doi: 10.1073/pnas.1219665110. Epub 2012 Dec 24. Erratum in: Proc Natl Acad Sci U S A. 2013 Feb 26;110(9):3651. Danniels, Jennifer [corrected to Daniels, Jennifer].

4.

Peptide targeting and imaging of damaged lung tissue in influenza-infected mice.

Li N, Yin L, Thévenin D, Yamada Y, Limmon G, Chen J, Chow VT, Engelman DM, Engelward BP.

Future Microbiol. 2013 Feb;8(2):257-69. doi: 10.2217/fmb.12.134.

5.

Inhibition of cancer cell proliferation and breast tumor targeting of pHLIP-monomethyl auristatin E conjugates.

Burns KE, Robinson MK, Thévenin D.

Mol Pharm. 2015 Apr 6;12(4):1250-8. doi: 10.1021/mp500779k. Epub 2015 Mar 13.

6.

[Mechanisms and strategies for targeting drugs to myocardial ischemic regions].

Sun GL, Lin X.

Yao Xue Xue Bao. 2010 Jul;45(7):827-32. Review. Chinese.

PMID:
20931778
7.
8.

pH-sensitive membrane peptides (pHLIPs) as a novel class of delivery agents.

Andreev OA, Engelman DM, Reshetnyak YK.

Mol Membr Biol. 2010 Oct;27(7):341-52. doi: 10.3109/09687688.2010.509285. Epub 2010 Oct 13. Review.

9.

Mechanism and uses of a membrane peptide that targets tumors and other acidic tissues in vivo.

Andreev OA, Dupuy AD, Segala M, Sandugu S, Serra DA, Chichester CO, Engelman DM, Reshetnyak YK.

Proc Natl Acad Sci U S A. 2007 May 8;104(19):7893-8. Epub 2007 May 1.

10.

The pH low insertion peptide pHLIP Variant 3 as a novel marker of acidic malignant lesions.

Tapmeier TT, Moshnikova A, Beech J, Allen D, Kinchesh P, Smart S, Harris A, McIntyre A, Engelman DM, Andreev OA, Reshetnyak YK, Muschel RJ.

Proc Natl Acad Sci U S A. 2015 Aug 4;112(31):9710-5. doi: 10.1073/pnas.1509488112. Epub 2015 Jul 20.

11.
12.

ATP-loaded liposomes for treatment of myocardial ischemia.

Hartner WC, Verma DD, Levchenko TS, Bernstein EA, Torchilin VP.

Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2009 Sep-Oct;1(5):530-9. doi: 10.1002/wnan.46. Review.

PMID:
20049815
13.

Antiproliferative effect of pHLIP-amanitin.

Moshnikova A, Moshnikova V, Andreev OA, Reshetnyak YK.

Biochemistry. 2013 Feb 19;52(7):1171-8. doi: 10.1021/bi301647y. Epub 2013 Feb 8.

14.

The relationships of high energy phosphates, tissue pH, and regional blood flow to diastolic distensibility in the ischemic dog myocardium.

Momomura S, Ingwall JS, Parker JA, Sahagian P, Ferguson JJ, Grossman W.

Circ Res. 1985 Dec;57(6):822-35.

15.

Targeting acidity in diseased tissues: mechanism and applications of the membrane-inserting peptide, pHLIP.

Deacon JC, Engelman DM, Barrera FN.

Arch Biochem Biophys. 2015 Jan 1;565:40-8. doi: 10.1016/j.abb.2014.11.002. Epub 2014 Nov 18.

16.

Roles of carboxyl groups in the transmembrane insertion of peptides.

Barrera FN, Weerakkody D, Anderson M, Andreev OA, Reshetnyak YK, Engelman DM.

J Mol Biol. 2011 Oct 21;413(2):359-71. doi: 10.1016/j.jmb.2011.08.010. Epub 2011 Aug 23.

17.

pHLIP®-mediated delivery of PEGylated liposomes to cancer cells.

Yao L, Daniels J, Wijesinghe D, Andreev OA, Reshetnyak YK.

J Control Release. 2013 May 10;167(3):228-37. doi: 10.1016/j.jconrel.2013.01.037. Epub 2013 Feb 15.

18.

Targeting diseased tissues by pHLIP insertion at low cell surface pH.

Andreev OA, Engelman DM, Reshetnyak YK.

Front Physiol. 2014 Mar 13;5:97. doi: 10.3389/fphys.2014.00097. eCollection 2014. Review.

19.

pH-controlled delivery of luminescent europium coated nanoparticles into platelets.

Davies A, Lewis DJ, Watson SP, Thomas SG, Pikramenou Z.

Proc Natl Acad Sci U S A. 2012 Feb 7;109(6):1862-7. doi: 10.1073/pnas.1112132109. Epub 2012 Jan 20.

20.

Regional changes in blood flow, extracellular potassium and conduction during myocardial ischemia and reperfusion.

Hariman RJ, Louie EK, Krahmer RL, Bremner SM, Euler D, Hwang MH, Ferguson JL, Loeb HS.

J Am Coll Cardiol. 1993 Mar 1;21(3):798-808.

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