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Items: 1 to 20 of 99

1.

β-Catenin-driven cancers require a YAP1 transcriptional complex for survival and tumorigenesis.

Rosenbluh J, Nijhawan D, Cox AG, Li X, Neal JT, Schafer EJ, Zack TI, Wang X, Tsherniak A, Schinzel AC, Shao DD, Schumacher SE, Weir BA, Vazquez F, Cowley GS, Root DE, Mesirov JP, Beroukhim R, Kuo CJ, Goessling W, Hahn WC.

Cell. 2012 Dec 21;151(7):1457-73. doi: 10.1016/j.cell.2012.11.026. Epub 2012 Dec 13. Erratum in: Cell. 2013 Mar 28;153(1):267-70.

2.

Activation of β-catenin and Yap1 in human hepatoblastoma and induction of hepatocarcinogenesis in mice.

Tao J, Calvisi DF, Ranganathan S, Cigliano A, Zhou L, Singh S, Jiang L, Fan B, Terracciano L, Armeanu-Ebinger S, Ribback S, Dombrowski F, Evert M, Chen X, Monga SPS.

Gastroenterology. 2014 Sep;147(3):690-701. doi: 10.1053/j.gastro.2014.05.004. Epub 2014 May 14.

3.

Mst1 and Mst2 protein kinases restrain intestinal stem cell proliferation and colonic tumorigenesis by inhibition of Yes-associated protein (Yap) overabundance.

Zhou D, Zhang Y, Wu H, Barry E, Yin Y, Lawrence E, Dawson D, Willis JE, Markowitz SD, Camargo FD, Avruch J.

Proc Natl Acad Sci U S A. 2011 Dec 6;108(49):E1312-20. doi: 10.1073/pnas.1110428108. Epub 2011 Oct 31.

4.

αE-catenin inhibits a Src-YAP1 oncogenic module that couples tyrosine kinases and the effector of Hippo signaling pathway.

Li P, Silvis MR, Honaker Y, Lien WH, Arron ST, Vasioukhin V.

Genes Dev. 2016 Apr 1;30(7):798-811. doi: 10.1101/gad.274951.115. Epub 2016 Mar 24.

5.

Alternate RASSF1 Transcripts Control SRC Activity, E-Cadherin Contacts, and YAP-Mediated Invasion.

Vlahov N, Scrace S, Soto MS, Grawenda AM, Bradley L, Pankova D, Papaspyropoulos A, Yee KS, Buffa F, Goding CR, Timpson P, Sibson N, O'Neill E.

Curr Biol. 2015 Dec 7;25(23):3019-34. doi: 10.1016/j.cub.2015.09.072. Epub 2015 Nov 5.

6.

Oncogenic function of DACT1 in colon cancer through the regulation of β-catenin.

Yuan G, Wang C, Ma C, Chen N, Tian Q, Zhang T, Fu W.

PLoS One. 2012;7(3):e34004. doi: 10.1371/journal.pone.0034004. Epub 2012 Mar 21.

7.

SETD7 Controls Intestinal Regeneration and Tumorigenesis by Regulating Wnt/β-Catenin and Hippo/YAP Signaling.

Oudhoff MJ, Braam MJS, Freeman SA, Wong D, Rattray DG, Wang J, Antignano F, Snyder K, Refaeli I, Hughes MR, McNagny KM, Gold MR, Arrowsmith CH, Sato T, Rossi FMV, Tatlock JH, Owen DR, Brown PJ, Zaph C.

Dev Cell. 2016 Apr 4;37(1):47-57. doi: 10.1016/j.devcel.2016.03.002.

8.

Specific oncogenic activity of the Src-family tyrosine kinase c-Yes in colon carcinoma cells.

Sancier F, Dumont A, Sirvent A, Paquay de Plater L, Edmonds T, David G, Jan M, de Montrion C, Cogé F, Léonce S, Burbridge M, Bruno A, Boutin JA, Lockhart B, Roche S, Cruzalegui F.

PLoS One. 2011 Feb 24;6(2):e17237. doi: 10.1371/journal.pone.0017237.

9.

Protein kinase C ζ is a positive modulator of canonical Wnt signaling pathway in tumoral colon cell lines.

Luna-Ulloa LB, Hernández-Maqueda JG, Santoyo-Ramos P, Castañeda-Patlán MC, Robles-Flores M.

Carcinogenesis. 2011 Nov;32(11):1615-24. doi: 10.1093/carcin/bgr190. Epub 2011 Aug 22.

PMID:
21859831
10.
11.

HEF1, a novel target of Wnt signaling, promotes colonic cell migration and cancer progression.

Li Y, Bavarva JH, Wang Z, Guo J, Qian C, Thibodeau SN, Golemis EA, Liu W.

Oncogene. 2011 Jun 9;30(23):2633-43. doi: 10.1038/onc.2010.632. Epub 2011 Feb 14.

12.

Nuclear Dvl, c-Jun, beta-catenin, and TCF form a complex leading to stabilization of beta-catenin-TCF interaction.

Gan XQ, Wang JY, Xi Y, Wu ZL, Li YP, Li L.

J Cell Biol. 2008 Mar 24;180(6):1087-100. doi: 10.1083/jcb.200710050. Epub 2008 Mar 17.

13.

RACK1 suppresses gastric tumorigenesis by stabilizing the β-catenin destruction complex.

Deng YZ, Yao F, Li JJ, Mao ZF, Hu PT, Long LY, Li G, Ji XD, Shi S, Guan DX, Feng YY, Cui L, Li DS, Liu Y, Du X, Guo MZ, Xu LY, Li EM, Wang HY, Xie D.

Gastroenterology. 2012 Apr;142(4):812-823.e15. doi: 10.1053/j.gastro.2011.12.046. Epub 2012 Jan 10.

PMID:
22240482
14.
15.

Aberrant nuclear localization of EBP50 promotes colorectal carcinogenesis in xenotransplanted mice by modulating TCF-1 and β-catenin interactions.

Lin YY, Hsu YH, Huang HY, Shann YJ, Huang CY, Wei SC, Chen CL, Jou TS.

J Clin Invest. 2012 May;122(5):1881-94. doi: 10.1172/JCI45661. Epub 2012 Apr 2.

16.

Endogenous protein kinase CK2 participates in Wnt signaling in mammary epithelial cells.

Song DH, Sussman DJ, Seldin DC.

J Biol Chem. 2000 Aug 4;275(31):23790-7.

17.

FOXKs promote Wnt/β-catenin signaling by translocating DVL into the nucleus.

Wang W, Li X, Lee M, Jun S, Aziz KE, Feng L, Tran MK, Li N, McCrea PD, Park JI, Chen J.

Dev Cell. 2015 Mar 23;32(6):707-18. doi: 10.1016/j.devcel.2015.01.031.

18.

Phosphorylation of Tyr188 in the WW domain of YAP1 plays an essential role in YAP1-induced cellular transformation.

Li YW, Guo J, Shen H, Li J, Yang N, Frangou C, Wilson KE, Zhang Y, Mussell AL, Sudol M, Farooq A, Qu J, Zhang J.

Cell Cycle. 2016 Sep 16;15(18):2497-505. doi: 10.1080/15384101.2016.1207836. Epub 2016 Jul 18.

19.

Dishevelled-2 docks and activates Src in a Wnt-dependent manner.

Yokoyama N, Malbon CC.

J Cell Sci. 2009 Dec 15;122(Pt 24):4439-51. doi: 10.1242/jcs.051847. Epub 2009 Nov 17.

20.

Peroxisome proliferator-activated receptor gamma (PPARgamma) suppresses colonic epithelial cell turnover and colon carcinogenesis through inhibition of the beta-catenin/T cell factor (TCF) pathway.

Fujisawa T, Nakajima A, Fujisawa N, Takahashi H, Ikeda I, Tomimoto A, Yonemitsu K, Nakajima N, Kudo C, Wada K, Kubota N, Terauchi Y, Kadowaki T, Nakagama H, Blumberg RS.

J Pharmacol Sci. 2008 Apr;106(4):627-38. Epub 2008 Apr 5.

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