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Anti-IFN-γ autoantibodies in adults with disseminated nontuberculous mycobacterial infections are associated with HLA-DRB1*16:02 and HLA-DQB1*05:02 and the reactivation of latent varicella-zoster virus infection.

Chi CY, Chu CC, Liu JP, Lin CH, Ho MW, Lo WJ, Lin PC, Chen HJ, Chou CH, Feng JY, Fung CP, Sher YP, Li CY, Wang JH, Ku CL.

Blood. 2013 Feb 21;121(8):1357-66. doi: 10.1182/blood-2012-08-452482. Epub 2012 Dec 13.


Autoantibodies against cytokines: back to human genetics.

Puel A, Casanova JL.

Blood. 2013 Feb 21;121(8):1246-7. doi: 10.1182/blood-2013-01-474213.


HLA-DRB1 and HLA-DQB1 Are Associated with Adult-Onset Immunodeficiency with Acquired Anti-Interferon-Gamma Autoantibodies.

Pithukpakorn M, Roothumnong E, Angkasekwinai N, Suktitipat B, Assawamakin A, Luangwedchakarn V, Umrod P, Thongnoppakhun W, Foongladda S, Suputtamongkol Y.

PLoS One. 2015 May 26;10(5):e0128481. doi: 10.1371/journal.pone.0128481. eCollection 2015.


Factors associated with acquired Anti IFN- γ autoantibody in patients with nontuberculous mycobacterial infection.

Phoompoung P, Ankasekwinai N, Pithukpakorn M, Foongladda S, Umrod P, Suktitipat B, Mahasirimongkol S, Kiertiburanakul S, Suputtamongkol Y.

PLoS One. 2017 Apr 24;12(4):e0176342. doi: 10.1371/journal.pone.0176342. eCollection 2017.


Anti-IFN-gamma autoantibodies in disseminated nontuberculous mycobacterial infections.

Patel SY, Ding L, Brown MR, Lantz L, Gay T, Cohen S, Martyak LA, Kubak B, Holland SM.

J Immunol. 2005 Oct 1;175(7):4769-76.


Anti-IFN-γ autoantibodies are strongly associated with HLA-DR*15:02/16:02 and HLA-DQ*05:01/05:02 across Southeast Asia.

Ku CL, Lin CH, Chang SW, Chu CC, Chan JF, Kong XF, Lee CH, Rosen EA, Ding JY, Lee WI, Bustamante J, Witte T, Shih HP, Kuo CY, Chetchotisakd P, Kiertiburanakul S, Suputtamongkol Y, Yuen KY, Casanova JL, Holland SM, Doffinger R, Browne SK, Chi CY.

J Allergy Clin Immunol. 2016 Mar;137(3):945-8.e8. doi: 10.1016/j.jaci.2015.09.018. Epub 2015 Oct 29. No abstract available.


Clinical manifestations, course, and outcome of patients with neutralizing anti-interferon-γ autoantibodies and disseminated nontuberculous mycobacterial infections.

Chi CY, Lin CH, Ho MW, Ding JY, Huang WC, Shih HP, Yeh CF, Fung CP, Sun HY, Huang CT, Wu TS, Chang CY, Liu YM, Feng JY, Wu WK, Wang LS, Tsai CH, Ho CM, Lin HS, Chen HJ, Lin PC, Liao WC, Chen WT, Lo CC, Wang SY, Kuo CY, Lee CH, Ku CL.

Medicine (Baltimore). 2016 Jun;95(25):e3927. doi: 10.1097/MD.0000000000003927.


Association of HLA class II markers with autoantibody-negative ketosis-prone atypical diabetes compared to type 2 diabetes in a population of sub-Saharan African patients.

Balti EV, Ngo-Nemb MC, Lontchi-Yimagou E, Atogho-Tiedeu B, Effoe VS, Akwo EA, Dehayem MY, Mbanya JC, Gautier JF, Sobngwi E.

Diabetes Res Clin Pract. 2015 Jan;107(1):31-6. doi: 10.1016/j.diabres.2014.10.002. Epub 2014 Nov 20.


HLA-DRB1*1501 and HLA-DQB1*0301 alleles are positively associated with HPV16 infection-related Kazakh esophageal squamous cell carcinoma in Xinjiang China.

Hu J, Li L, Pang L, Chen Y, Yang L, Liu C, Zhao J, Chang B, Qi Y, Liang W, Li F.

Cancer Immunol Immunother. 2012 Nov;61(11):2135-41. doi: 10.1007/s00262-012-1281-x. Epub 2012 May 16.


Genetic association of HLA-DQB1 and HLA-DRB1 polymorphisms with alopecia areata in the Italian population.

Megiorni F, Pizzuti A, Mora B, Rizzuti A, Garelli V, Maxia C, Carlesimo M, Fotruna MC, Delle Chiaie R, Cavaggioni G, Rossi A.

Br J Dermatol. 2011 Oct;165(4):823-7. doi: 10.1111/j.1365-2133.2011.10466.x. Epub 2011 Sep 15.


The effect of HLA on immunological response to hepatitis B vaccine in healthy people: a meta-analysis.

Li ZK, Nie JJ, Li J, Zhuang H.

Vaccine. 2013 Sep 13;31(40):4355-61. doi: 10.1016/j.vaccine.2013.06.108. Epub 2013 Jul 23.


Disseminated Mycobacterium gordonae and Mycobacterium mantenii infection with elevated anti-IFN-γ neutralizing autoantibodies.

Hase I, Morimoto K, Sakagami T, Kazumi Y, Ishii Y, van Ingen J.

J Infect Chemother. 2015 Jun;21(6):468-72. doi: 10.1016/j.jiac.2015.02.003. Epub 2015 Feb 12.


Naturally occurring anti-IFN-gamma autoantibody and severe infections with Mycobacterium cheloneae and Burkholderia cocovenenans.

Höflich C, Sabat R, Rosseau S, Temmesfeld B, Slevogt H, Döcke WD, Grütz G, Meisel C, Halle E, Göbel UB, Volk HD, Suttorp N.

Blood. 2004 Jan 15;103(2):673-5. Epub 2003 Aug 28.


Mucous membrane pemphigoid: HLA-DQB1*0301 is associated with all clinical sites of involvement and may be linked to antibasement membrane IgG production.

Setterfield J, Theron J, Vaughan RW, Welsh KI, Mallon E, Wojnarowska F, Challacombe SJ, Black MM.

Br J Dermatol. 2001 Sep;145(3):406-14.


The influence of the HLA-DRB1 and HLA-DQB1 allele heterogeneity on disease risk and severity in Iranian patients with multiple sclerosis.

Kollaee A, Ghaffarpor M, Ghlichnia HA, Ghaffari SH, Zamani M.

Int J Immunogenet. 2012 Oct;39(5):414-22. doi: 10.1111/j.1744-313X.2012.01104.x. Epub 2012 Mar 9.


Late-Onset Disseminated Mycobacterium avium intracellulare Complex Infection (MAC), Cerebral Toxoplasmosis and Salmonella Sepsis in a German Caucasian Patient with Unusual Anti-Interferon-Gamma IgG1 Autoantibodies.

Hanitsch LG, Löbel M, Müller-Redetzky H, Schürmann M, Suttorp N, Unterwalder N, Mönnich U, Meisel C, Wittke K, Volk HD, Scheibenbogen C, Kölsch U.

J Clin Immunol. 2015 May;35(4):361-5. doi: 10.1007/s10875-015-0161-5. Epub 2015 Apr 15.


Clinical Sindbis alphavirus infection is associated with HLA-DRB1*01 allele and production of autoantibodies.

Sane J, Kurkela S, Lokki ML, Miettinen A, Helve T, Vaheri A, Vapalahti O.

Clin Infect Dis. 2012 Aug;55(3):358-63. doi: 10.1093/cid/cis405. Epub 2012 Apr 20.


[Relationship between pneumoconiosis and the polymorphisms of HLA-DRB1*, DQB1* genes].

Fan XY, Li JZ, Yao SQ, Yan JD, Li CL, Ma QK.

Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2005 Aug;23(4):278-81. Chinese.


Rituximab as successful adjunct treatment in a patient with disseminated nontuberculous mycobacterial infection due to acquired anti-interferon-γ autoantibody.

Czaja CA, Merkel PA, Chan ED, Lenz LL, Wolf ML, Alam R, Frankel SK, Fischer A, Gogate S, Perez-Velez CM, Knight V.

Clin Infect Dis. 2014 Mar;58(6):e115-8. doi: 10.1093/cid/cit809. Epub 2013 Dec 11.


Patients with inhibitory and neutralizing auto-antibodies to interferon-γ resemble the sporadic adult-onset phenotype of Mendelian Susceptibility to Mycobacterial Disease (MSMD) lacking Bacille Calmette-Guerin (BCG)-induced diseases.

Lee WI, Huang JL, Wu TS, Lee MH, Chen IJ, Yu KH, Liu CY, Yang CH, Hsieh MY, Lin YL, Shih YF, Jaing TH, Huang SC, Kuo TT, Ku CL.

Immunobiology. 2013 May;218(5):762-71. doi: 10.1016/j.imbio.2012.08.281. Epub 2012 Aug 31.


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