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Items: 1 to 20 of 95

1.

ANT2 suppression by shRNA may be able to exert anticancer effects in HCC further by restoring SOCS1 expression.

Jang JY, Jeon YK, Lee CE, Kim CW.

Int J Oncol. 2013 Feb;42(2):574-82. doi: 10.3892/ijo.2012.1736. Epub 2012 Dec 13.

PMID:
23242177
2.

ANT2 suppression by shRNA restores miR-636 expression, thereby downregulating Ras and inhibiting tumorigenesis of hepatocellular carcinoma.

Jang JY, Lee YS, Jeon YK, Lee K, Jang JJ, Kim CW.

Exp Mol Med. 2013 Jan 10;45:e3. doi: 10.1038/emm.2013.1.

3.

ANT2 shRNA downregulates miR-19a and miR-96 through the PI3K/Akt pathway and suppresses tumor growth in hepatocellular carcinoma cells.

Baik SH, Lee J, Lee YS, Jang JY, Kim CW.

Exp Mol Med. 2016 Mar 25;48:e222. doi: 10.1038/emm.2015.126.

5.

Combined RNA interference of adenine nucleotide translocase-2 and ganciclovir therapy in hepatocellular carcinoma.

Kim JE, Hwang MH, Lee HW, Lee SW, Lee J, Ahn BC.

Nucl Med Biol. 2013 Nov;40(8):987-93. doi: 10.1016/j.nucmedbio.2013.08.004. Epub 2013 Sep 17.

PMID:
24054501
6.

Potent antitumor activity of oncolytic adenovirus-mediated SOCS1 for hepatocellular carcinoma.

Liu L, Li W, Wei X, Cui Q, Lou W, Wang G, Hu X, Qian C.

Gene Ther. 2013 Jan;20(1):84-92. doi: 10.1038/gt.2012.4. Epub 2012 Feb 9.

PMID:
22318090
7.

Ubiquitous activation of Ras and Jak/Stat pathways in human HCC.

Calvisi DF, Ladu S, Gorden A, Farina M, Conner EA, Lee JS, Factor VM, Thorgeirsson SS.

Gastroenterology. 2006 Apr;130(4):1117-28.

PMID:
16618406
8.

Degradation of HER2/neu by ANT2 shRNA suppresses migration and invasiveness of breast cancer cells.

Jang JY, Jeon YK, Kim CW.

BMC Cancer. 2010 Jul 23;10:391. doi: 10.1186/1471-2407-10-391.

9.

Epigenetic downregulation of the suppressor of cytokine signaling 1 (Socs1) gene is associated with the STAT3 activation and development of hepatocellular carcinoma induced by methyl-deficiency in rats.

Bagnyukova TV, Tryndyak VP, Muskhelishvili L, Ross SA, Beland FA, Pogribny IP.

Cell Cycle. 2008 Oct;7(20):3202-10. Epub 2008 Oct 18.

PMID:
18843197
10.

SOCS-1, a negative regulator of the JAK/STAT pathway, is silenced by methylation in human hepatocellular carcinoma and shows growth-suppression activity.

Yoshikawa H, Matsubara K, Qian GS, Jackson P, Groopman JD, Manning JE, Harris CC, Herman JG.

Nat Genet. 2001 May;28(1):29-35.

PMID:
11326271
11.

Epigenetic alteration of the SOCS1 gene in hepatocellular carcinoma.

Chu PY, Yeh CM, Hsu NC, Chang YS, Chang JG, Yeh KT.

Swiss Med Wkly. 2010 Jul 15;140:w13065. doi: 10.4414/smw.2010.13065.

PMID:
20648401
12.

Regulation of MET receptor tyrosine kinase signaling by suppressor of cytokine signaling 1 in hepatocellular carcinoma.

Gui Y, Yeganeh M, Donates YC, Tobelaim WS, Chababi W, Mayhue M, Yoshimura A, Ramanathan S, Saucier C, Ilangumaran S.

Oncogene. 2015 Nov 12;34(46):5718-28. doi: 10.1038/onc.2015.20. Epub 2015 Mar 2.

PMID:
25728680
13.

The helicase HAGE prevents interferon-α-induced PML expression in ABCB5+ malignant melanoma-initiating cells by promoting the expression of SOCS1.

Mathieu MG, Miles AK, Ahmad M, Buczek ME, Pockley AG, Rees RC, Regad T.

Cell Death Dis. 2014 Feb 13;5:e1061. doi: 10.1038/cddis.2014.29.

14.

Methylation silencing of SOCS-3 promotes cell growth and migration by enhancing JAK/STAT and FAK signalings in human hepatocellular carcinoma.

Niwa Y, Kanda H, Shikauchi Y, Saiura A, Matsubara K, Kitagawa T, Yamamoto J, Kubo T, Yoshikawa H.

Oncogene. 2005 Sep 22;24(42):6406-17.

PMID:
16007195
15.

MicroRNA-155 functions as an OncomiR in breast cancer by targeting the suppressor of cytokine signaling 1 gene.

Jiang S, Zhang HW, Lu MH, He XH, Li Y, Gu H, Liu MF, Wang ED.

Cancer Res. 2010 Apr 15;70(8):3119-27. doi: 10.1158/0008-5472.CAN-09-4250. Epub 2010 Mar 30.

16.

Histone deacetylases inhibitor sodium butyrate inhibits JAK2/STAT signaling through upregulation of SOCS1 and SOCS3 mediated by HDAC8 inhibition in myeloproliferative neoplasms.

Gao SM, Chen CQ, Wang LY, Hong LL, Wu JB, Dong PH, Yu FJ.

Exp Hematol. 2013 Mar;41(3):261-70.e4. doi: 10.1016/j.exphem.2012.10.012. Epub 2012 Oct 27.

PMID:
23111066
17.

Enforced SOCS1 and SOCS3 expression attenuates Lck-mediated cellular transformation.

Cooper JC, Shi M, Chueh FY, Venkitachalam S, Yu CL.

Int J Oncol. 2010 May;36(5):1201-8.

18.
19.

Association of APC, GSTP1 and SOCS1 promoter methylation with the risk of hepatocellular carcinoma: a meta-analysis.

Liu M, Cui LH, Li CC, Zhang L.

Eur J Cancer Prev. 2015 Nov;24(6):470-83. doi: 10.1097/CEJ.0000000000000121.

PMID:
25853848
20.

MicroRNA-148a is silenced by hypermethylation and interacts with DNA methyltransferase 1 in hepatocellular carcinogenesis.

Long XR, He Y, Huang C, Li J.

Int J Oncol. 2014 Jun;44(6):1915-22. doi: 10.3892/ijo.2014.2373. Epub 2014 Apr 8.

PMID:
24714841

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