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Items: 1 to 20 of 316

1.

The p63 protein isoform ΔNp63α inhibits epithelial-mesenchymal transition in human bladder cancer cells: role of MIR-205.

Tran MN, Choi W, Wszolek MF, Navai N, Lee IL, Nitti G, Wen S, Flores ER, Siefker-Radtke A, Czerniak B, Dinney C, Barton M, McConkey DJ.

J Biol Chem. 2013 Feb 1;288(5):3275-88. doi: 10.1074/jbc.M112.408104. Epub 2012 Dec 13.

2.

ΔNp63α attenuates tumor aggressiveness by suppressing miR-205/ZEB1-mediated epithelial-mesenchymal transition in cervical squamous cell carcinoma.

Zhao W, Wang H, Han X, Ma J, Zhou Y, Chen Z, Zhou H, Xu H, Sun Z, Kong B, Fang H.

Tumour Biol. 2016 Aug;37(8):10621-32. doi: 10.1007/s13277-016-4921-5. Epub 2016 Feb 10.

PMID:
26864590
3.

MicroRNA-23b functions as a tumor suppressor by regulating Zeb1 in bladder cancer.

Majid S, Dar AA, Saini S, Deng G, Chang I, Greene K, Tanaka Y, Dahiya R, Yamamura S.

PLoS One. 2013 Jul 2;8(7):e67686. doi: 10.1371/journal.pone.0067686. Print 2013.

4.

Role of miR-200c/miR-141 in the regulation of epithelial-mesenchymal transition and migration in head and neck squamous cell carcinoma.

Tamagawa S, Beder LB, Hotomi M, Gunduz M, Yata K, Grenman R, Yamanaka N.

Int J Mol Med. 2014 Apr;33(4):879-86. doi: 10.3892/ijmm.2014.1625. Epub 2014 Jan 14.

PMID:
24424572
5.
6.

p63 expression defines a lethal subset of muscle-invasive bladder cancers.

Choi W, Shah JB, Tran M, Svatek R, Marquis L, Lee IL, Yu D, Adam L, Wen S, Shen Y, Dinney C, McConkey DJ, Siefker-Radtke A.

PLoS One. 2012;7(1):e30206. doi: 10.1371/journal.pone.0030206. Epub 2012 Jan 10.

7.

Loss of the polycomb protein Mel-18 enhances the epithelial-mesenchymal transition by ZEB1 and ZEB2 expression through the downregulation of miR-205 in breast cancer.

Lee JY, Park MK, Park JH, Lee HJ, Shin DH, Kang Y, Lee CH, Kong G.

Oncogene. 2014 Mar 6;33(10):1325-35. doi: 10.1038/onc.2013.53. Epub 2013 Mar 11.

PMID:
23474752
8.

Long non-coding RNA urothelial cancer-associated 1 promotes bladder cancer cell migration and invasion by way of the hsa-miR-145-ZEB1/2-FSCN1 pathway.

Xue M, Pang H, Li X, Li H, Pan J, Chen W.

Cancer Sci. 2016 Jan;107(1):18-27. doi: 10.1111/cas.12844. Epub 2015 Dec 11.

9.

A Polycomb-mir200 loop regulates clinical outcome in bladder cancer.

Martínez-Fernández M, Dueñas M, Feber A, Segovia C, García-Escudero R, Rubio C, López-Calderón FF, Díaz-García C, Villacampa F, Duarte J, Gómez-Rodriguez MJ, Castellano D, Rodriguez-Peralto JL, de la Rosa F, Beck S, Paramio JM.

Oncotarget. 2015 Dec 8;6(39):42258-75. doi: 10.18632/oncotarget.5546.

10.

The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2.

Park SM, Gaur AB, Lengyel E, Peter ME.

Genes Dev. 2008 Apr 1;22(7):894-907. doi: 10.1101/gad.1640608. Erratum in: Genes Dev. 2009 Jun 1;23(11):1378.

11.

MiR-652 inhibits acidic microenvironment-induced epithelial-mesenchymal transition of pancreatic cancer cells by targeting ZEB1.

Deng S, Li X, Niu Y, Zhu S, Jin Y, Deng S, Chen J, Liu Y, He C, Yin T, Yang Z, Tao J, Xiong J, Wu H, Wang C, Zhao G.

Oncotarget. 2015 Nov 24;6(37):39661-75. doi: 10.18632/oncotarget.5350.

12.

Epithelial-mesenchymal transition, a novel target of sulforaphane via COX-2/MMP2, 9/Snail, ZEB1 and miR-200c/ZEB1 pathways in human bladder cancer cells.

Shan Y, Zhang L, Bao Y, Li B, He C, Gao M, Feng X, Xu W, Zhang X, Wang S.

J Nutr Biochem. 2013 Jun;24(6):1062-9. doi: 10.1016/j.jnutbio.2012.08.004. Epub 2012 Nov 13.

PMID:
23159064
13.

miR-200 promotes the mesenchymal to epithelial transition by suppressing multiple members of the Zeb2 and Snail1 transcriptional repressor complexes.

Perdigão-Henriques R, Petrocca F, Altschuler G, Thomas MP, Le MT, Tan SM, Hide W, Lieberman J.

Oncogene. 2016 Jan 14;35(2):158-72. doi: 10.1038/onc.2015.69. Epub 2015 Mar 23.

PMID:
25798844
14.

miR-139-5p inhibits epithelial-mesenchymal transition, migration and invasion of hepatocellular carcinoma cells by targeting ZEB1 and ZEB2.

Qiu G, Lin Y, Zhang H, Wu D.

Biochem Biophys Res Commun. 2015 Jul 31;463(3):315-21. doi: 10.1016/j.bbrc.2015.05.062. Epub 2015 May 27.

PMID:
26022123
15.

Downregulated microRNA-200a promotes EMT and tumor growth through the wnt/β-catenin pathway by targeting the E-cadherin repressors ZEB1/ZEB2 in gastric adenocarcinoma.

Cong N, Du P, Zhang A, Shen F, Su J, Pu P, Wang T, Zjang J, Kang C, Zhang Q.

Oncol Rep. 2013 Apr;29(4):1579-87. doi: 10.3892/or.2013.2267. Epub 2013 Jan 31.

PMID:
23381389
16.

MicroRNA-200b regulates cell proliferation, invasion, and migration by directly targeting ZEB2 in gastric carcinoma.

Kurashige J, Kamohara H, Watanabe M, Hiyoshi Y, Iwatsuki M, Tanaka Y, Kinoshita K, Saito S, Baba Y, Baba H.

Ann Surg Oncol. 2012 Jul;19 Suppl 3:S656-64. doi: 10.1245/s10434-012-2217-6. Epub 2012 Feb 4.

PMID:
22311119
17.

Double-negative feedback loop between ZEB2 and miR-145 regulates epithelial-mesenchymal transition and stem cell properties in prostate cancer cells.

Ren D, Wang M, Guo W, Huang S, Wang Z, Zhao X, Du H, Song L, Peng X.

Cell Tissue Res. 2014 Dec;358(3):763-78. doi: 10.1007/s00441-014-2001-y. Epub 2014 Oct 9.

PMID:
25296715
18.

miR-200 expression regulates epithelial-to-mesenchymal transition in bladder cancer cells and reverses resistance to epidermal growth factor receptor therapy.

Adam L, Zhong M, Choi W, Qi W, Nicoloso M, Arora A, Calin G, Wang H, Siefker-Radtke A, McConkey D, Bar-Eli M, Dinney C.

Clin Cancer Res. 2009 Aug 15;15(16):5060-72. doi: 10.1158/1078-0432.CCR-08-2245. Epub 2009 Aug 11.

19.

MiR203 mediates subversion of stem cell properties during mammary epithelial differentiation via repression of ΔNP63α and promotes mesenchymal-to-epithelial transition.

DeCastro AJ, Dunphy KA, Hutchinson J, Balboni AL, Cherukuri P, Jerry DJ, DiRenzo J.

Cell Death Dis. 2013 Feb 28;4:e514. doi: 10.1038/cddis.2013.37.

20.

The miR-200 family inhibits epithelial-mesenchymal transition and cancer cell migration by direct targeting of E-cadherin transcriptional repressors ZEB1 and ZEB2.

Korpal M, Lee ES, Hu G, Kang Y.

J Biol Chem. 2008 May 30;283(22):14910-4. doi: 10.1074/jbc.C800074200. Epub 2008 Apr 14.

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