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Items: 1 to 20 of 84

1.

Serotonin and GI Disorders: An Update on Clinical and Experimental Studies.

Manocha M, Khan WI.

Clin Transl Gastroenterol. 2012 Apr 26;3:e13. doi: 10.1038/ctg.2012.8.

2.

Diverse Effects of Gut-Derived Serotonin in Intestinal Inflammation.

Shajib MS, Baranov A, Khan WI.

ACS Chem Neurosci. 2017 May 17;8(5):920-931. doi: 10.1021/acschemneuro.6b00414. Epub 2017 Mar 27.

PMID:
28288510
3.

The role of serotonin and its receptors in activation of immune responses and inflammation.

Shajib MS, Khan WI.

Acta Physiol (Oxf). 2015 Mar;213(3):561-74. doi: 10.1111/apha.12430. Epub 2014 Dec 11. Review.

PMID:
25439045
4.

IL-13-mediated immunological control of enterochromaffin cell hyperplasia and serotonin production in the gut.

Manocha M, Shajib MS, Rahman MM, Wang H, Rengasamy P, Bogunovic M, Jordana M, Mayer L, Khan WI.

Mucosal Immunol. 2013 Jan;6(1):146-55. doi: 10.1038/mi.2012.58. Epub 2012 Jul 4.

PMID:
22763407
5.

Serotonin and GI clinical disorders.

Spiller R.

Neuropharmacology. 2008 Nov;55(6):1072-80. doi: 10.1016/j.neuropharm.2008.07.016. Epub 2008 Jul 19. Review.

PMID:
18687345
6.

Gut hormones: emerging role in immune activation and inflammation.

Khan WI, Ghia JE.

Clin Exp Immunol. 2010 Jul 1;161(1):19-27. doi: 10.1111/j.1365-2249.2010.04150.x. Epub 2010 Apr 9. Review.

7.

Serotonin and its role in colonic function and in gastrointestinal disorders.

Costedio MM, Hyman N, Mawe GM.

Dis Colon Rectum. 2007 Mar;50(3):376-88. Review.

PMID:
17195902
8.

Enterochromaffin cells and 5-HT signaling in the pathophysiology of disorders of gastrointestinal function.

Crowell MD, Shetzline MA, Moses PL, Mawe GM, Talley NJ.

Curr Opin Investig Drugs. 2004 Jan;5(1):55-60. Review.

PMID:
14983974
9.

Discovery and characterization of novel tryptophan hydroxylase inhibitors that selectively inhibit serotonin synthesis in the gastrointestinal tract.

Liu Q, Yang Q, Sun W, Vogel P, Heydorn W, Yu XQ, Hu Z, Yu W, Jonas B, Pineda R, Calderon-Gay V, Germann M, O'Neill E, Brommage R, Cullinan E, Platt K, Wilson A, Powell D, Sands A, Zambrowicz B, Shi ZC.

J Pharmacol Exp Ther. 2008 Apr;325(1):47-55. doi: 10.1124/jpet.107.132670. Epub 2008 Jan 11.

10.

Molecular defects in mucosal serotonin content and decreased serotonin reuptake transporter in ulcerative colitis and irritable bowel syndrome.

Coates MD, Mahoney CR, Linden DR, Sampson JE, Chen J, Blaszyk H, Crowell MD, Sharkey KA, Gershon MD, Mawe GM, Moses PL.

Gastroenterology. 2004 Jun;126(7):1657-64.

PMID:
15188158
11.

5-HT system in the gut: roles in the regulation of visceral sensitivity and motor functions.

Grundy D.

Eur Rev Med Pharmacol Sci. 2008 Aug;12 Suppl 1:63-7. Review.

PMID:
18924445
12.

5-HT7 receptor signaling: improved therapeutic strategy in gut disorders.

Kim JJ, Khan WI.

Front Behav Neurosci. 2014 Dec 11;8:396. doi: 10.3389/fnbeh.2014.00396. eCollection 2014. Review.

14.

Enterochromaffin cell and 5-hydroxytryptamine responses to the same infectious agent differ in Th1 and Th2 dominant environments.

Motomura Y, Ghia JE, Wang H, Akiho H, El-Sharkawy RT, Collins M, Wan Y, McLaughlin JT, Khan WI.

Gut. 2008 Apr;57(4):475-81. doi: 10.1136/gut.2007.129296. Epub 2008 Jan 15. Erratum in: Gut. 2008 Sep;57(9):1340.

PMID:
18198200
15.

The serotonin signaling system: from basic understanding to drug development for functional GI disorders.

Gershon MD, Tack J.

Gastroenterology. 2007 Jan;132(1):397-414. Review.

PMID:
17241888
16.
17.

CD4+ T cell-mediated immunological control of enterochromaffin cell hyperplasia and 5-hydroxytryptamine production in enteric infection.

Wang H, Steeds J, Motomura Y, Deng Y, Verma-Gandhu M, El-Sharkawy RT, McLaughlin JT, Grencis RK, Khan WI.

Gut. 2007 Jul;56(7):949-57. Epub 2007 Feb 15.

18.

Serotonin release and uptake in the gastrointestinal tract.

Bertrand PP, Bertrand RL.

Auton Neurosci. 2010 Feb 16;153(1-2):47-57. doi: 10.1016/j.autneu.2009.08.002. Epub 2009 Sep 2. Review.

PMID:
19729349
19.

Serotonin has a key role in pathogenesis of experimental colitis.

Ghia JE, Li N, Wang H, Collins M, Deng Y, El-Sharkawy RT, Côté F, Mallet J, Khan WI.

Gastroenterology. 2009 Nov;137(5):1649-60. doi: 10.1053/j.gastro.2009.08.041. Epub 2009 Aug 23.

PMID:
19706294
20.

Role of serotonin in gastrointestinal physiology and pathology.

Cirillo C, Vanden Berghe P, Tack J.

Minerva Endocrinol. 2011 Dec;36(4):311-24. Review.

PMID:
22322654

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