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Items: 1 to 20 of 292

1.

Efficiency and effectiveness of the use of an acenocoumarol pharmacogenetic dosing algorithm versus usual care in patients with venous thromboembolic disease initiating oral anticoagulation: study protocol for a randomized controlled trial.

Carcas AJ, Borobia AM, Velasco M, Abad-Santos F, Díaz MQ, Fernández-Capitán C, Ruiz-Giménez N, Madridano O, Sillero PL; PGX-ACE Spanish Investigators Group.

Trials. 2012 Dec 13;13:239. doi: 10.1186/1745-6215-13-239.

2.

Evaluation of a pharmacogenetic-based warfarin dosing algorithm in patients with low time in therapeutic range - study protocol for a randomized controlled trial.

Marcatto LR, Sacilotto L, Bueno CT, Facin M, Strunz CM, Darrieux FC, Scanavacca MI, Krieger JE, Pereira AC, Santos PC.

BMC Cardiovasc Disord. 2016 Nov 17;16(1):224.

3.

Genotype-guided therapy improves initial acenocoumarol dosing. Results from a prospective randomised study.

Cerezo-Manchado JJ, Roldán V, Corral J, Rosafalco M, Antón AI, Padilla J, Vicente V, González-Conejero R.

Thromb Haemost. 2016 Jan;115(1):117-25. doi: 10.1160/TH14-09-0814. Epub 2015 Nov 5.

PMID:
26538428
4.

Dosing algorithms for vitamin K antagonists across VKORC1 and CYP2C9 genotypes.

Baranova EV, Verhoef TI, Ragia G, le Cessie S, Asselbergs FW, de Boer A, Manolopoulos VG, Maitland-van der Zee AH; EU-PACT group.

J Thromb Haemost. 2017 Mar;15(3):465-472. doi: 10.1111/jth.13615. Epub 2017 Feb 17.

5.

Ability of VKORC1 and CYP2C9 to predict therapeutic warfarin dose during the initial weeks of therapy.

Ferder NS, Eby CS, Deych E, Harris JK, Ridker PM, Milligan PE, Goldhaber SZ, King CR, Giri T, McLeod HL, Glynn RJ, Gage BF.

J Thromb Haemost. 2010 Jan;8(1):95-100. doi: 10.1111/j.1538-7836.2009.03677.x. Epub 2009 Oct 30.

6.

An acenocoumarol dosing algorithm using clinical and pharmacogenetic data in Spanish patients with thromboembolic disease.

Borobia AM, Lubomirov R, Ramírez E, Lorenzo A, Campos A, Muñoz-Romo R, Fernández-Capitán C, Frías J, Carcas AJ.

PLoS One. 2012;7(7):e41360. doi: 10.1371/journal.pone.0041360. Epub 2012 Jul 20.

7.

Optimization of vitamin K antagonist drug dose finding by replacement of the international normalized ratio by a bidirectional factor: validation of a new algorithm.

Beinema MJ, van der Meer FJ, Brouwers JR, Rosendaal FR.

J Thromb Haemost. 2016 Mar;14(3):479-84. doi: 10.1111/jth.13240. Epub 2016 Feb 9.

8.

A randomized trial of genotype-guided dosing of acenocoumarol and phenprocoumon.

Verhoef TI, Ragia G, de Boer A, Barallon R, Kolovou G, Kolovou V, Konstantinides S, Le Cessie S, Maltezos E, van der Meer FJ, Redekop WK, Remkes M, Rosendaal FR, van Schie RM, Tavridou A, Tziakas D, Wadelius M, Manolopoulos VG, Maitland-van der Zee AH; EU-PACT Group.

N Engl J Med. 2013 Dec 12;369(24):2304-12. doi: 10.1056/NEJMoa1311388. Epub 2013 Nov 19.

9.

Creating a genotype-based dosing algorithm for acenocoumarol steady dose.

Cerezo-Manchado JJ, Rosafalco M, Antón AI, Pérez-Andreu V, Garcia-Barberá N, Martinez AB, Corral J, Vicente V, González-Conejero R, Roldán V.

Thromb Haemost. 2013 Jan;109(1):146-53. doi: 10.1160/TH12-08-0631. Epub 2012 Nov 29.

PMID:
23196355
10.

Pharmacogenetics role in the safety of acenocoumarol therapy.

Jiménez-Varo E, Cañadas-Garre M, Henriques CI, Pinheiro AM, Gutiérrez-Pimentel MJ, Calleja-Hernández MÁ.

Thromb Haemost. 2014 Sep 2;112(3):522-36. doi: 10.1160/TH13-11-0941. Epub 2014 Jun 12.

PMID:
24919870
11.

Pharmacogenetic differences between warfarin, acenocoumarol and phenprocoumon.

Beinema M, Brouwers JR, Schalekamp T, Wilffert B.

Thromb Haemost. 2008 Dec;100(6):1052-7. Review.

PMID:
19132230
12.

Prediction of stable acenocoumarol dose by a pharmacogenetic algorithm.

Jiménez-Varo E, Cañadas-Garre M, Gutiérrez-Pimentel MJ, Calleja-Hernández MA.

Pharmacogenet Genomics. 2014 Oct;24(10):501-13. doi: 10.1097/FPC.0000000000000082.

PMID:
25089947
13.

A New Pharmacogenetic Algorithm to Predict the Most Appropriate Dosage of Acenocoumarol for Stable Anticoagulation in a Mixed Spanish Population.

Tong HY, Dávila-Fajardo CL, Borobia AM, Martínez-González LJ, Lubomirov R, Perea León LM, Blanco Bañares MJ, Díaz-Villamarín X, Fernández-Capitán C, Cabeza Barrera J, Carcas AJ; PGX-ACE Investigators Group.

PLoS One. 2016 Mar 15;11(3):e0150456. doi: 10.1371/journal.pone.0150456. eCollection 2016.

14.

Pharmacogenetics-based warfarin dosing algorithm decreases time to stable anticoagulation and the risk of major hemorrhage: an updated meta-analysis of randomized controlled trials.

Wang ZQ, Zhang R, Zhang PP, Liu XH, Sun J, Wang J, Feng XF, Lu QF, Li YG.

J Cardiovasc Pharmacol. 2015 Apr;65(4):364-70. doi: 10.1097/FJC.0000000000000204.

PMID:
25551322
15.

Genotype-Guided Dosing of Coumarin Anticoagulants: A Meta-analysis of Randomized Controlled Trials.

Tang T, Liu J, Zuo K, Cheng J, Chen L, Lu C, Han S, Xu J, Jia Z, Ye M, Pei E, Zhang X, Li M.

J Cardiovasc Pharmacol Ther. 2015 Jul;20(4):387-94. doi: 10.1177/1074248414565666. Epub 2015 Jan 8.

PMID:
25575537
16.

Genotype-guided vs clinical dosing of warfarin and its analogues: meta-analysis of randomized clinical trials.

Stergiopoulos K, Brown DL.

JAMA Intern Med. 2014 Aug;174(8):1330-8. doi: 10.1001/jamainternmed.2014.2368.

PMID:
24935087
17.

Edoxaban for the long-term treatment of venous thromboembolism: rationale and design of the Hokusai-venous thromboembolism study--methodological implications for clinical trials.

Raskob G, Büller H, Prins M, Segers A, Shi M, Schwocho L, van Kranen R, Mercuri M; Hokusai-VTE Investigators.

J Thromb Haemost. 2013 Jul;11(7):1287-94. doi: 10.1111/jth.12230.

18.

Initiation of oral anticoagulant therapy in orthopedic and surgical patients: an algorithm compared with routine dosing.

van den Bemt PM, Beinema M, van Roon EN, Sijtsma J, Baars WA, Mencke HJ, Brouwers JR.

Eur J Clin Pharmacol. 2002 Jun;58(3):203-208.

PMID:
12162272
19.

Acenocoumarol Pharmacogenetic Dosing Algorithms and Their Application in Two Bulgarian Patients with Low Anticoagulant Requirements.

Dimitrova-Karamfilova A, Tzveova R, Chilingirova N, Goranova T, Nachev G, Mitev V, Kaneva R.

Biochem Genet. 2015 Dec;53(11-12):334-50. doi: 10.1007/s10528-015-9695-8. Epub 2015 Sep 16.

PMID:
26377995
20.

A randomized trial of genotype-guided dosing of warfarin.

Pirmohamed M, Burnside G, Eriksson N, Jorgensen AL, Toh CH, Nicholson T, Kesteven P, Christersson C, Wahlström B, Stafberg C, Zhang JE, Leathart JB, Kohnke H, Maitland-van der Zee AH, Williamson PR, Daly AK, Avery P, Kamali F, Wadelius M; EU-PACT Group.

N Engl J Med. 2013 Dec 12;369(24):2294-303. doi: 10.1056/NEJMoa1311386. Epub 2013 Nov 19.

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