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N-acetylation and phosphorylation of Sec complex subunits in the ER membrane.

Soromani C, Zeng N, Hollemeyer K, Heinzle E, Klein MC, Tretter T, Seaman MN, Römisch K.

BMC Cell Biol. 2012 Dec 13;13:34. doi: 10.1186/1471-2121-13-34.


The transmembrane domain is sufficient for Sbh1p function, its association with the Sec61 complex, and interaction with Rtn1p.

Feng D, Zhao X, Soromani C, Toikkanen J, Römisch K, Vembar SS, Brodsky JL, Keränen S, Jäntti J.

J Biol Chem. 2007 Oct 19;282(42):30618-28. Epub 2007 Aug 14.


A second trimeric complex containing homologs of the Sec61p complex functions in protein transport across the ER membrane of S. cerevisiae.

Finke K, Plath K, Panzner S, Prehn S, Rapoport TA, Hartmann E, Sommer T.

EMBO J. 1996 Apr 1;15(7):1482-94.


The Brl domain in Sec63p is required for assembly of functional endoplasmic reticulum translocons.

Jermy AJ, Willer M, Davis E, Wilkinson BM, Stirling CJ.

J Biol Chem. 2006 Mar 24;281(12):7899-906. Epub 2005 Dec 20.


ERAD and protein import defects in a sec61 mutant lacking ER-lumenal loop 7.

Tretter T, Pereira FP, Ulucan O, Helms V, Allan S, Kalies KU, Römisch K.

BMC Cell Biol. 2013 Dec 6;14:56. doi: 10.1186/1471-2121-14-56.


Sss1p is required to complete protein translocon activation.

Wilkinson BM, Brownsword JK, Mousley CJ, Stirling CJ.

J Biol Chem. 2010 Oct 15;285(42):32671-7. doi: 10.1074/jbc.M110.128256. Epub 2010 Aug 13.


Mammalian Sec61 is associated with Sec62 and Sec63.

Meyer HA, Grau H, Kraft R, Kostka S, Prehn S, Kalies KU, Hartmann E.

J Biol Chem. 2000 May 12;275(19):14550-7.


Stability and function of the Sec61 translocation complex depends on the Sss1p tail-anchor sequence.

Falcone D, Henderson MP, Nieuwland H, Coughlan CM, Brodsky JL, Andrews DW.

Biochem J. 2011 Jun 1;436(2):291-303. doi: 10.1042/BJ20101865.


Analysis of Sec61p and Ssh1p interactions in the ER membrane using the split-ubiquitin system.

Harty C, Römisch K.

BMC Cell Biol. 2013 Mar 11;14:14. doi: 10.1186/1471-2121-14-14.


Subunits of the translocon interact with components of the oligosaccharyl transferase complex.

Chavan M, Yan A, Lennarz WJ.

J Biol Chem. 2005 Jun 17;280(24):22917-24. Epub 2005 Apr 14.


Defective ER associated degradation of a model luminal substrate in yeast carrying a mutation in the 4th ER luminal loop of Sec61p.

Wheeler MC, Gekakis N.

Biochem Biophys Res Commun. 2012 Nov 2;427(4):768-73. doi: 10.1016/j.bbrc.2012.09.136. Epub 2012 Oct 5.


ER membrane protein complex required for nuclear fusion.

Ng DT, Walter P.

J Cell Biol. 1996 Feb;132(4):499-509.


Role of human sec63 in modulating the steady-state levels of multi-spanning membrane proteins.

Mades A, Gotthardt K, Awe K, Stieler J, Döring T, Füser S, Prange R.

PLoS One. 2012;7(11):e49243. doi: 10.1371/journal.pone.0049243. Epub 2012 Nov 15.


Molecular architecture of the ER translocase probed by chemical crosslinking of Sss1p to complementary fragments of Sec61p.

Wilkinson BM, Esnault Y, Craven RA, Skiba F, Fieschi J, K'epès F, Stirling CJ.

EMBO J. 1997 Aug 1;16(15):4549-59.


Coordination of N-glycosylation and protein translocation across the endoplasmic reticulum membrane by Sss1 protein.

Scheper W, Thaminy S, Kais S, Stagljar I, Römisch K.

J Biol Chem. 2003 Sep 26;278(39):37998-8003. Epub 2003 Jul 14.


SSS1 encodes a stabilizing component of the Sec61 subcomplex of the yeast protein translocation apparatus.

Esnault Y, Feldheim D, Blondel MO, Schekman R, Képès F.

J Biol Chem. 1994 Nov 4;269(44):27478-85.

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