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Items: 1 to 20 of 147


Dissection of a quantitative trait locus for PR interval duration identifies Tnni3k as a novel modulator of cardiac conduction.

Lodder EM, Scicluna BP, Milano A, Sun AY, Tang H, Remme CA, Moerland PD, Tanck MW, Pitt GS, Marchuk DA, Bezzina CR.

PLoS Genet. 2012;8(12):e1003113. doi: 10.1371/journal.pgen.1003113.


Quantitative trait loci for electrocardiographic parameters and arrhythmia in the mouse.

Scicluna BP, Tanck MW, Remme CA, Beekman L, Coronel R, Wilde AA, Bezzina CR.

J Mol Cell Cardiol. 2011 Mar;50(3):380-9. doi: 10.1016/j.yjmcc.2010.09.009.


QTL mapping in a mouse model of cardiomyopathy reveals an ancestral modifier allele affecting heart function and survival.

Wheeler FC, Fernandez L, Carlson KM, Wolf MJ, Rockman HA, Marchuk DA.

Mamm Genome. 2005 Jun;16(6):414-23.


Quantitative genetics of age-related retinal degeneration: a second F1 intercross between the A/J and C57BL/6 strains.

Danciger M, Yang H, Ralston R, Liu Y, Matthes MT, Peirce J, Lavail MM.

Mol Vis. 2007 Jan 25;13:79-85.


TNNI3K mutation in familial syndrome of conduction system disease, atrial tachyarrhythmia and dilated cardiomyopathy.

Theis JL, Zimmermann MT, Larsen BT, Rybakova IN, Long PA, Evans JM, Middha S, de Andrade M, Moss RL, Wieben ED, Michels VV, Olson TM.

Hum Mol Genet. 2014 Nov 1;23(21):5793-804. doi: 10.1093/hmg/ddu297.


Integrative genomic approach identifies multiple genes involved in cardiac collagen deposition.

Lodder EM, Scicluna BP, Beekman L, Arends D, Moerland PD, Tanck MW, Adriaens ME, Bezzina CR.

Circ Cardiovasc Genet. 2014 Dec;7(6):790-8. doi: 10.1161/CIRCGENETICS.114.000537.


Fine mapping of collagen-induced arthritis quantitative trait loci in an advanced intercross line.

Yu X, Bauer K, Wernhoff P, Koczan D, Möller S, Thiesen HJ, Ibrahim SM.

J Immunol. 2006 Nov 15;177(10):7042-9.


Using gene expression databases for classical trait QTL candidate gene discovery in the BXD recombinant inbred genetic reference population: mouse forebrain weight.

Lu L, Wei L, Peirce JL, Wang X, Zhou J, Homayouni R, Williams RW, Airey DC.

BMC Genomics. 2008 Sep 25;9:444. doi: 10.1186/1471-2164-9-444.


Several common variants modulate heart rate, PR interval and QRS duration.

Holm H, Gudbjartsson DF, Arnar DO, Thorleifsson G, Thorgeirsson G, Stefansdottir H, Gudjonsson SA, Jonasdottir A, Mathiesen EB, Njølstad I, Nyrnes A, Wilsgaard T, Hald EM, Hveem K, Stoltenberg C, Løchen ML, Kong A, Thorsteinsdottir U, Stefansson K.

Nat Genet. 2010 Feb;42(2):117-22. doi: 10.1038/ng.511.


Further studies on using multiple-cross mapping (MCM) to map quantitative trait loci.

Malmanger B, Lawler M, Coulombe S, Murray R, Cooper S, Polyakov Y, Belknap J, Hitzemann R.

Mamm Genome. 2006 Dec;17(12):1193-204.


Genome-wide analysis of hepatic fibrosis in inbred mice identifies the susceptibility locus Hfib1 on chromosome 15.

Hillebrandt S, Goos C, Matern S, Lammert F.

Gastroenterology. 2002 Dec;123(6):2041-51.


In silico quantitative trait locus map for atherosclerosis susceptibility in apolipoprotein E-deficient mice.

Smith JD, James D, Dansky HM, Wittkowski KM, Moore KJ, Breslow JL.

Arterioscler Thromb Vasc Biol. 2003 Jan 1;23(1):117-22.


Genome-wide association study of electrocardiographic conduction measures in an isolated founder population: Kosrae.

Smith JG, Lowe JK, Kovvali S, Maller JB, Salit J, Daly MJ, Stoffel M, Altshuler DM, Friedman JM, Breslow JL, Newton-Cheh C.

Heart Rhythm. 2009 May;6(5):634-41. doi: 10.1016/j.hrthm.2009.02.022.


Quantitative trait loci affecting atherosclerosis at the aortic root identified in an intercross between DBA2J and 129S6 apolipoprotein E-null mice.

Kayashima Y, Tomita H, Zhilicheva S, Kim S, Kim HS, Bennett BJ, Maeda N.

PLoS One. 2014 Feb 20;9(2):e88274. doi: 10.1371/journal.pone.0088274.


Sensitivity to the locomotor-stimulant effects of ethanol and allopregnanolone: a quantitative trait locus study of common genetic influence.

Palmer AA, Lessov-Schlaggar CN, Ponder CA, McKinnon CS, Phillips TJ.

Genes Brain Behav. 2006 Oct;5(7):506-17.


Genetic analysis of albuminuria in a cross between C57BL/6J and DBA/2J mice.

Sheehan S, Tsaih SW, King BL, Stanton C, Churchill GA, Paigen B, DiPetrillo K.

Am J Physiol Renal Physiol. 2007 Nov;293(5):F1649-56.


Methodological aspects of the genetic dissection of gene expression.

Carlborg O, De Koning DJ, Manly KF, Chesler E, Williams RW, Haley CS.

Bioinformatics. 2005 May 15;21(10):2383-93.


Genetic dissection of quantitative trait loci specifying sedative/hypnotic sensitivity to ethanol: mapping with interval-specific congenic recombinant lines.

Bennett B, Beeson M, Gordon L, Carosone-Link P, Johnson TE.

Alcohol Clin Exp Res. 2002 Nov;26(11):1615-24.


Confirmation of multiple seizure susceptibility QTLs on chromosome 15 in C57BL/6J and DBA/2J inbred mice.

Ferraro TN, Smith GG, Schwebel CL, Doyle GA, Ruiz SE, Oleynick JU, Lohoff FW, Berrettini WH, Buono RJ.

Physiol Genomics. 2010 Sep;42A(1):1-7. doi: 10.1152/physiolgenomics.00096.2010.

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