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Items: 1 to 20 of 64

1.

Endothelin axis is upregulated in human and rat right ventricular hypertrophy.

Nagendran J, Sutendra G, Paterson I, Champion HC, Webster L, Chiu B, Haromy A, Rebeyka IM, Ross DB, Michelakis ED.

Circ Res. 2013 Jan 18;112(2):347-54. doi: 10.1161/CIRCRESAHA.111.300448. Epub 2012 Dec 10. Erratum in: Circ Res. 2014 Mar 14;114(6):e32.

2.

Unlooked-for significance of cardiac versus vascular effects of endothelin-1 in the pathophysiology of pulmonary arterial hypertension.

Taguchi K, Hattori Y.

Circ Res. 2013 Jan 18;112(2):227-9. doi: 10.1161/CIRCRESAHA.112.300623. No abstract available.

3.

Phosphodiesterase type 5 is highly expressed in the hypertrophied human right ventricle, and acute inhibition of phosphodiesterase type 5 improves contractility.

Nagendran J, Archer SL, Soliman D, Gurtu V, Moudgil R, Haromy A, St Aubin C, Webster L, Rebeyka IM, Ross DB, Light PE, Dyck JR, Michelakis ED.

Circulation. 2007 Jul 17;116(3):238-48. Epub 2007 Jul 2.

4.

Letter to the editor on Nagendran et al.

Lazarus HM.

Circ Res. 2014 Mar 14;114(6):e30. doi: 10.1161/CIRCRESAHA.114.303707. No abstract available.

5.

Response to Lazarus.

Michelakis ED.

Circ Res. 2014 Mar 14;114(6):e31. doi: 10.1161/CIRCRESAHA.114.303719. No abstract available.

6.

GRK2-mediated inhibition of adrenergic and dopaminergic signaling in right ventricular hypertrophy: therapeutic implications in pulmonary hypertension.

Piao L, Fang YH, Parikh KS, Ryan JJ, D'Souza KM, Theccanat T, Toth PT, Pogoriler J, Paul J, Blaxall BC, Akhter SA, Archer SL.

Circulation. 2012 Dec 11;126(24):2859-69. doi: 10.1161/CIRCULATIONAHA.112.109868. Epub 2012 Nov 2.

7.

Allogenic stem cell therapy improves right ventricular function by improving lung pathology in rats with pulmonary hypertension.

Umar S, de Visser YP, Steendijk P, Schutte CI, Laghmani el H, Wagenaar GT, Bax WH, Mantikou E, Pijnappels DA, Atsma DE, Schalij MJ, van der Wall EE, van der Laarse A.

Am J Physiol Heart Circ Physiol. 2009 Nov;297(5):H1606-16. doi: 10.1152/ajpheart.00590.2009. Epub 2009 Sep 25.

PMID:
19783775
8.

Cardiomyocyte-specific overexpression of HEXIM1 prevents right ventricular hypertrophy in hypoxia-induced pulmonary hypertension in mice.

Yoshikawa N, Shimizu N, Maruyama T, Sano M, Matsuhashi T, Fukuda K, Kataoka M, Satoh T, Ojima H, Sawai T, Morimoto C, Kuribara A, Hosono O, Tanaka H.

PLoS One. 2012;7(12):e52522. doi: 10.1371/journal.pone.0052522. Epub 2012 Dec 31.

9.

Bosentan attenuates right ventricular hypertrophy and fibrosis in normobaric hypoxia model of pulmonary hypertension.

Choudhary G, Troncales F, Martin D, Harrington EO, Klinger JR.

J Heart Lung Transplant. 2011 Jul;30(7):827-33. doi: 10.1016/j.healun.2011.03.010. Epub 2011 May 8.

10.

Activation of signaling molecules and matrix metalloproteinases in right ventricular myocardium of rats with pulmonary hypertension.

Umar S, Hessel M, Steendijk P, Bax W, Schutte C, Schalij M, van der Wall E, Atsma D, van der Laarse A.

Pathol Res Pract. 2007;203(12):863-72. Epub 2007 Oct 29.

PMID:
17913382
11.

The inhibition of pyruvate dehydrogenase kinase improves impaired cardiac function and electrical remodeling in two models of right ventricular hypertrophy: resuscitating the hibernating right ventricle.

Piao L, Fang YH, Cadete VJ, Wietholt C, Urboniene D, Toth PT, Marsboom G, Zhang HJ, Haber I, Rehman J, Lopaschuk GD, Archer SL.

J Mol Med (Berl). 2010 Jan;88(1):47-60. doi: 10.1007/s00109-009-0524-6. Epub 2009 Dec 1.

12.

A miR-208-Mef2 axis drives the decompensation of right ventricular function in pulmonary hypertension.

Paulin R, Sutendra G, Gurtu V, Dromparis P, Haromy A, Provencher S, Bonnet S, Michelakis ED.

Circ Res. 2015 Jan 2;116(1):56-69. doi: 10.1161/CIRCRESAHA.115.303910. Epub 2014 Oct 6.

13.

A dynamic and chamber-specific mitochondrial remodeling in right ventricular hypertrophy can be therapeutically targeted.

Nagendran J, Gurtu V, Fu DZ, Dyck JR, Haromy A, Ross DB, Rebeyka IM, Michelakis ED.

J Thorac Cardiovasc Surg. 2008 Jul;136(1):168-78, 178.e1-3. doi: 10.1016/j.jtcvs.2008.01.040. Epub 2008 May 23.

14.

Therapeutic inhibition of fatty acid oxidation in right ventricular hypertrophy: exploiting Randle's cycle.

Fang YH, Piao L, Hong Z, Toth PT, Marsboom G, Bache-Wiig P, Rehman J, Archer SL.

J Mol Med (Berl). 2012 Jan;90(1):31-43. doi: 10.1007/s00109-011-0804-9. Epub 2011 Aug 28.

15.

Effects of physiological or pathological pressure load in vivo on myocardial expression of ET-1 and receptors.

Ueno M, Miyauchi T, Sakai S, Kobayashi T, Goto K, Yamaguchi I.

Am J Physiol. 1999 Nov;277(5 Pt 2):R1321-30.

PMID:
10564203
16.

Cardiac glutaminolysis: a maladaptive cancer metabolism pathway in the right ventricle in pulmonary hypertension.

Piao L, Fang YH, Parikh K, Ryan JJ, Toth PT, Archer SL.

J Mol Med (Berl). 2013 Oct;91(10):1185-97. doi: 10.1007/s00109-013-1064-7. Epub 2013 Jun 21.

17.

Right ventricular oxygen supply parameters are decreased in human and experimental pulmonary hypertension.

Ruiter G, Ying Wong Y, de Man FS, Louis Handoko M, Jaspers RT, Postmus PE, Westerhof N, Niessen HW, van der Laarse WJ, Vonk-Noordegraaf A.

J Heart Lung Transplant. 2013 Feb;32(2):231-40. doi: 10.1016/j.healun.2012.09.025. Epub 2012 Nov 9.

PMID:
23142560
19.
20.

Biventricular structural and functional responses to aortic constriction in a rabbit model of chronic right ventricular pressure overload.

Apitz C, Honjo O, Humpl T, Li J, Assad RS, Cho MY, Hong J, Friedberg MK, Redington AN.

J Thorac Cardiovasc Surg. 2012 Dec;144(6):1494-501. doi: 10.1016/j.jtcvs.2012.06.027. Epub 2012 Jul 18.

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