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Items: 1 to 20 of 103

1.

Intravenous genetic mesothelin vaccine based on human adenovirus 40 inhibits growth and metastasis of pancreatic cancer.

Yamasaki S, Miura Y, Davydova J, Vickers SM, Yamamoto M.

Int J Cancer. 2013 Jul;133(1):88-97. doi: 10.1002/ijc.27983. Epub 2012 Dec 21.

2.

Dendritic cells adenovirally-transduced with full-length mesothelin cDNA elicit mesothelin-specific cytotoxicity against pancreatic cancer cell lines in vitro.

Miyazawa M, Iwahashi M, Ojima T, Katsuda M, Nakamura M, Nakamori M, Ueda K, Naka T, Hayata K, Iida T, Yamaue H.

Cancer Lett. 2011 Jun 1;305(1):32-9. doi: 10.1016/j.canlet.2011.02.013.

PMID:
21397388
3.

Dual antigen target-based immunotherapy for prostate cancer eliminates the growth of established tumors in mice.

Karan D, Dubey S, Van Veldhuizen P, Holzbeierlein JM, Tawfik O, Thrasher JB.

Immunotherapy. 2011 Jun;3(6):735-46. doi: 10.2217/imt.11.59.

PMID:
21668311
4.

A live-attenuated Listeria vaccine (ANZ-100) and a live-attenuated Listeria vaccine expressing mesothelin (CRS-207) for advanced cancers: phase I studies of safety and immune induction.

Le DT, Brockstedt DG, Nir-Paz R, Hampl J, Mathur S, Nemunaitis J, Sterman DH, Hassan R, Lutz E, Moyer B, Giedlin M, Louis JL, Sugar EA, Pons A, Cox AL, Levine J, Murphy AL, Illei P, Dubensky TW Jr, Eiden JE, Jaffee EM, Laheru DA.

Clin Cancer Res. 2012 Feb 1;18(3):858-68. doi: 10.1158/1078-0432.CCR-11-2121. Epub 2011 Dec 6.

5.

An ISCOM vaccine combined with a TLR9 agonist breaks immune evasion mediated by regulatory T cells in an orthotopic model of pancreatic carcinoma.

Jacobs C, Duewell P, Heckelsmiller K, Wei J, Bauernfeind F, Ellermeier J, Kisser U, Bauer CA, Dauer M, Eigler A, Maraskovsky E, Endres S, Schnurr M.

Int J Cancer. 2011 Feb 15;128(4):897-907. doi: 10.1002/ijc.25399.

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8.

A novel mycobacterial Hsp70-containing fusion protein targeting mesothelin augments antitumor immunity and prolongs survival in murine models of ovarian cancer and mesothelioma.

Yuan J, Kashiwagi S, Reeves P, Nezivar J, Yang Y, Arrifin NH, Nguyen M, Jean-Mary G, Tong X, Uppal P, Korochkina S, Forbes B, Chen T, Righi E, Bronson R, Chen H, Orsulic S, Brauns T, Leblanc P, Scholler N, Dranoff G, Gelfand J, Poznansky MC.

J Hematol Oncol. 2014 Feb 24;7:15. doi: 10.1186/1756-8722-7-15.

9.

Mesothelin virus-like particle immunization controls pancreatic cancer growth through CD8+ T cell induction and reduction in the frequency of CD4+ foxp3+ ICOS- regulatory T cells.

Zhang S, Yong LK, Li D, Cubas R, Chen C, Yao Q.

PLoS One. 2013 Jul 9;8(7):e68303. doi: 10.1371/journal.pone.0068303. Print 2013.

10.

Low-dose adenovirus vaccine encoding chimeric hepatitis B virus surface antigen-human papillomavirus type 16 E7 proteins induces enhanced E7-specific antibody and cytotoxic T-cell responses.

Báez-Astúa A, Herráez-Hernández E, Garbi N, Pasolli HA, Juárez V, Zur Hausen H, Cid-Arregui A.

J Virol. 2005 Oct;79(20):12807-17.

11.

Development of improved therapeutic mesothelin-based vaccines for pancreatic cancer.

White M, Freistaedter A, Jones GJB, Zervos E, Roper RL.

PLoS One. 2018 Feb 23;13(2):e0193131. doi: 10.1371/journal.pone.0193131. eCollection 2018.

12.

MUC1-specific CTLs are non-functional within a pancreatic tumor microenvironment.

Mukherjee P, Ginardi AR, Madsen CS, Tinder TL, Jacobs F, Parker J, Agrawal B, Longenecker BM, Gendler SJ.

Glycoconj J. 2001 Nov-Dec;18(11-12):931-42.

PMID:
12820727
13.

Control of human mesothelin-expressing tumors by DNA vaccines.

Chang CL, Wu TC, Hung CF.

Gene Ther. 2007 Aug;14(16):1189-98. Epub 2007 Jun 21.

15.

Concomitant gemcitabine therapy negatively affects DC vaccine-induced CD8(+) T-cell and B-cell responses but improves clinical efficacy in a murine pancreatic carcinoma model.

Bauer C, Sterzik A, Bauernfeind F, Duewell P, Conrad C, Kiefl R, Endres S, Eigler A, Schnurr M, Dauer M.

Cancer Immunol Immunother. 2014 Apr;63(4):321-33. doi: 10.1007/s00262-013-1510-y. Epub 2014 Jan 3.

PMID:
24384835
16.
17.

A single intraduodenal administration of human adenovirus 40 vaccine effectively prevents anaphylactic shock.

Yamasaki S, Miura Y, Davydova J, Vickers SM, Yamamoto M.

Clin Vaccine Immunol. 2013 Oct;20(10):1508-16. doi: 10.1128/CVI.00417-13. Epub 2013 Jul 24.

18.

Dendritic cells transduced with recombinant adenoviruses induce more efficient anti-tumor immunity than dendritic cells pulsed with peptide.

Oh ST, Kim CH, Park MY, Won EH, Sohn HJ, Cho HI, Kang WK, Hong YK, Kim TG.

Vaccine. 2006 Apr 5;24(15):2860-8. Epub 2006 Jan 13.

PMID:
16443309
19.

Induction of protective and therapeutic anti-pancreatic cancer immunity using a reconstructed MUC1 DNA vaccine.

Rong Y, Jin D, Wu W, Lou W, Wang D, Kuang T, Ni X, Qin X.

BMC Cancer. 2009 Jun 18;9:191. doi: 10.1186/1471-2407-9-191.

20.

Proapoptotic and antiapoptotic proteins of the Bcl-2 family regulate sensitivity of pancreatic cancer cells toward gemcitabine and T-cell-mediated cytotoxicity.

Bauer C, Hees C, Sterzik A, Bauernfeind F, Mak'Anyengo R, Duewell P, Lehr HA, Noessner E, Wank R, Trauzold A, Endres S, Dauer M, Schnurr M.

J Immunother. 2015 Apr;38(3):116-26. doi: 10.1097/CJI.0000000000000073.

PMID:
25751501

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