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Items: 1 to 20 of 115

1.

Blood-to-brain influx transport of nicotine at the rat blood-brain barrier: involvement of a pyrilamine-sensitive organic cation transport process.

Tega Y, Akanuma S, Kubo Y, Terasaki T, Hosoya K.

Neurochem Int. 2013 Jan;62(2):173-81. doi: 10.1016/j.neuint.2012.11.014. Epub 2012 Dec 7.

PMID:
23228345
2.

Carrier-Mediated Transport of Nicotine Across the Inner Blood-Retinal Barrier: Involvement of a Novel Organic Cation Transporter Driven by an Outward H(+) Gradient.

Tega Y, Kubo Y, Yuzurihara C, Akanuma S, Hosoya K.

J Pharm Sci. 2015 Sep;104(9):3069-75. doi: 10.1002/jps.24453. Epub 2015 Apr 17.

PMID:
25892000
3.

Involvement of the pyrilamine transporter, a putative organic cation transporter, in blood-brain barrier transport of oxycodone.

Okura T, Hattori A, Takano Y, Sato T, Hammarlund-Udenaes M, Terasaki T, Deguchi Y.

Drug Metab Dispos. 2008 Oct;36(10):2005-13. doi: 10.1124/dmd.108.022087. Epub 2008 Jul 7.

4.

Involvement of a novel organic cation transporter in verapamil transport across the inner blood-retinal barrier.

Kubo Y, Kusagawa Y, Tachikawa M, Akanuma S, Hosoya K.

Pharm Res. 2013 Mar;30(3):847-56. doi: 10.1007/s11095-012-0926-y. Epub 2012 Nov 22.

PMID:
23179781
5.

Blood-brain barrier is involved in the efflux transport of a neuroactive steroid, dehydroepiandrosterone sulfate, via organic anion transporting polypeptide 2.

Asaba H, Hosoya K, Takanaga H, Ohtsuki S, Tamura E, Takizawa T, Terasaki T.

J Neurochem. 2000 Nov;75(5):1907-16.

6.

Involvement of the H+/organic cation antiporter in nicotine transport in rat liver.

Tega Y, Akanuma S, Kubo Y, Hosoya K.

Drug Metab Dispos. 2015 Jan;43(1):89-92. doi: 10.1124/dmd.114.061002. Epub 2014 Oct 28.

7.

Involvement of an influx transporter in the blood-brain barrier transport of naloxone.

Suzuki T, Ohmuro A, Miyata M, Furuishi T, Hidaka S, Kugawa F, Fukami T, Tomono K.

Biopharm Drug Dispos. 2010 May;31(4):243-52. doi: 10.1002/bdd.707.

PMID:
20437463
8.

mRna expression and transport characterization of conditionally immortalized rat brain capillary endothelial cell lines; a new in vitro BBB model for drug targeting.

Hosoya KI, Takashima T, Tetsuka K, Nagura T, Ohtsuki S, Takanaga H, Ueda M, Yanai N, Obinata M, Terasaki T.

J Drug Target. 2000;8(6):357-70.

PMID:
11328662
9.

Involvement of carrier-mediated transport in the retinal uptake of clonidine at the inner blood-retinal barrier.

Kubo Y, Tsuchiyama A, Shimizu Y, Akanuma S, Hosoya K.

Mol Pharm. 2014 Oct 6;11(10):3747-53. doi: 10.1021/mp500516j. Epub 2014 Sep 26.

PMID:
25222277
10.

Blood-brain barrier transport of pramipexole, a dopamine D2 agonist.

Okura T, Ito R, Ishiguro N, Tamai I, Deguchi Y.

Life Sci. 2007 Apr 3;80(17):1564-71. Epub 2007 Jan 27.

PMID:
17307202
11.

Involvement of OCTN2 in the transport of acetyl-L-carnitine across the inner blood-retinal barrier.

Tachikawa M, Takeda Y, Tomi M, Hosoya K.

Invest Ophthalmol Vis Sci. 2010 Jan;51(1):430-6. doi: 10.1167/iovs.09-4080. Epub 2009 Aug 13.

PMID:
19684012
12.

Recent advances in the brain-to-blood efflux transport across the blood-brain barrier.

Hosoya K, Ohtsuki S, Terasaki T.

Int J Pharm. 2002 Nov 6;248(1-2):15-29. Review.

PMID:
12429456
13.

Possible involvement of cationic-drug sensitive transport systems in the blood-to-brain influx and brain-to-blood efflux of amantadine across the blood-brain barrier.

Suzuki T, Fukami T, Tomono K.

Biopharm Drug Dispos. 2015 Mar;36(2):126-37. doi: 10.1002/bdd.1926. Epub 2014 Dec 21.

PMID:
25410756
15.

The acetylcholinesterase inhibitors competitively inhibited an acetyl L-carnitine transport through the blood-brain barrier.

Lee NY, Choi HO, Kang YS.

Neurochem Res. 2012 Jul;37(7):1499-507. doi: 10.1007/s11064-012-0723-3. Epub 2012 Feb 23.

PMID:
22359054
16.

ATA2 is predominantly expressed as system A at the blood-brain barrier and acts as brain-to-blood efflux transport for L-proline.

Takanaga H, Tokuda N, Ohtsuki S, Hosoya K, Terasaki T.

Mol Pharmacol. 2002 Jun;61(6):1289-96.

17.

Involvement of a proton-coupled organic cation antiporter in the blood-brain barrier transport of amantadine.

Suzuki T, Aoyama T, Suzuki N, Kobayashi M, Fukami T, Matsumoto Y, Tomono K.

Biopharm Drug Dispos. 2016 Sep;37(6):323-35. doi: 10.1002/bdd.2014. Epub 2016 Aug 24. Erratum in: Biopharm Drug Dispos. 2016 Nov;37(8):507.

PMID:
27146715
18.

Brain to blood efflux transport of adenosine: blood-brain barrier studies in the rat.

Isakovic AJ, Abbott NJ, Redzic ZB.

J Neurochem. 2004 Jul;90(2):272-86.

19.

Rat brain endothelial cell lines for the study of blood-brain barrier permeability and transport functions.

Roux F, Couraud PO.

Cell Mol Neurobiol. 2005 Feb;25(1):41-58. Review.

PMID:
15962508
20.

Involvement of organic anion transporters in the efflux of uremic toxins across the blood-brain barrier.

Deguchi T, Isozaki K, Yousuke K, Terasaki T, Otagiri M.

J Neurochem. 2006 Feb;96(4):1051-9.

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