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Items: 1 to 20 of 106

1.

CD4+ T cells recognize diverse epitopes within GAD65: implications for repertoire development and diabetes monitoring.

Yang J, James EA, Sanda S, Greenbaum C, Kwok WW.

Immunology. 2013 Mar;138(3):269-79. doi: 10.1111/imm.12034.

3.

Identification of naturally processed T cell epitopes from glutamic acid decarboxylase presented in the context of HLA-DR alleles by T lymphocytes of recent onset IDDM patients.

Endl J, Otto H, Jung G, Dreisbusch B, Donie F, Stahl P, Elbracht R, Schmitz G, Meinl E, Hummel M, Ziegler AG, Wank R, Schendel DJ.

J Clin Invest. 1997 May 15;99(10):2405-15.

4.

Glutamic acid decarboxylase T lymphocyte responses associated with susceptibility or resistance to type I diabetes: analysis in disease discordant human twins, non-obese diabetic mice and HLA-DQ transgenic mice.

Boyton RJ, Lohmann T, Londei M, Kalbacher H, Halder T, Frater AJ, Douek DC, Leslie DG, Flavell RA, Altmann DM.

Int Immunol. 1998 Dec;10(12):1765-76.

PMID:
9885897
5.

Complexity of human immune response profiles for CD4+ T cell epitopes from the diabetes autoantigen GAD65.

Masewicz SA, Meldrum N, Gersuk V, Gaur L, Hagopian W, Moriarity L, Nepom GT.

Autoimmunity. 2001;34(4):231-40.

PMID:
11905849
6.

Comparative study of GAD65-specific CD4+ T cells in healthy and type 1 diabetic subjects.

Danke NA, Yang J, Greenbaum C, Kwok WW.

J Autoimmun. 2005 Dec;25(4):303-11. Epub 2005 Oct 24.

PMID:
16249070
7.

Recognition of posttranslationally modified GAD65 epitopes in subjects with type 1 diabetes.

McGinty JW, Chow IT, Greenbaum C, Odegard J, Kwok WW, James EA.

Diabetes. 2014 Sep;63(9):3033-40. doi: 10.2337/db13-1952. Epub 2014 Apr 4.

8.

GAD65- and proinsulin-specific CD4+ T-cells detected by MHC class II tetramers in peripheral blood of type 1 diabetes patients and at-risk subjects.

Oling V, Marttila J, Ilonen J, Kwok WW, Nepom G, Knip M, Simell O, Reijonen H.

J Autoimmun. 2005 Nov;25(3):235-43. Epub 2005 Nov 2. Erratum in: J Autoimmun. 2006 Aug;27(1):69.

PMID:
16263242
9.

Recognition of Ii-Key/MHC class II epitope hybrids derived from proinsulin and GAD peptides by T cells in type 1 diabetes.

Vadacca M, Valorani MG, von Hofe E, Kallinteris NL, Buzzetti R, Pozzilli P.

Horm Metab Res. 2011 Jun;43(7):483-8. doi: 10.1055/s-0031-1275705. Epub 2011 Apr 21.

PMID:
21512962
10.

Identification of mimicry peptides based on sequential motifs of epitopes derived from 65-kDa glutamic acid decarboxylase.

Bach JM, Otto H, Jung G, Cohen H, Boitard C, Bach JF, van Endert PM.

Eur J Immunol. 1998 Jun;28(6):1902-10.

11.

Major DQ8-restricted T-cell epitopes for human GAD65 mapped using human CD4, DQA1*0301, DQB1*0302 transgenic IA(null) NOD mice.

Liu J, Purdy LE, Rabinovitch S, Jevnikar AM, Elliott JF.

Diabetes. 1999 Mar;48(3):469-77.

PMID:
10078545
12.

Identification of immunodominant T cell epitopes of human glutamic acid decarboxylase 65 by using HLA-DR(alpha1*0101,beta1*0401) transgenic mice.

Patel SD, Cope AP, Congia M, Chen TT, Kim E, Fugger L, Wherrett D, Sonderstrup-McDevitt G.

Proc Natl Acad Sci U S A. 1997 Jul 22;94(15):8082-7.

13.
14.

Autoreactive human T-cell receptor initiates insulitis and impaired glucose tolerance in HLA DR4 transgenic mice.

Gebe JA, Unrath KA, Yue BB, Miyake T, Falk BA, Nepom GT.

J Autoimmun. 2008 Jun;30(4):197-206. Epub 2007 Oct 18.

15.

T cell response pattern to glutamic acid decarboxylase 65 (GAD65) peptides of newly diagnosed type 1 diabetic patients sharing susceptible HLA haplotypes.

Rharbaoui F, Mayer A, Granier C, Bouanani M, Thivolet C, Pau B, Orgiazzi J, Madec AM.

Clin Exp Immunol. 1999 Jul;117(1):30-7.

16.

Characterization of self-glutamic acid decarboxylase 65-reactive CD4+ T-cell clones established from Japanese patients with insulin-dependent diabetes mellitus.

Tabata H, Kanai T, Yoshizumi H, Nishiyama S, Fujimoto S, Matsuda I, Yasukawa M, Matsushita S, Nishimura Y.

Hum Immunol. 1998 Sep;59(9):549-60.

PMID:
9757911
17.

Evidence for molecular mimicry between human T cell epitopes in rotavirus and pancreatic islet autoantigens.

Honeyman MC, Stone NL, Falk BA, Nepom G, Harrison LC.

J Immunol. 2010 Feb 15;184(4):2204-10. doi: 10.4049/jimmunol.0900709. Epub 2010 Jan 18.

18.

Identification of peptides from autoantigens GAD65 and IA-2 that bind to HLA class II molecules predisposing to or protecting from type 1 diabetes.

Harfouch-Hammoud E, Walk T, Otto H, Jung G, Bach JF, van Endert PM, Caillat-Zucman S.

Diabetes. 1999 Oct;48(10):1937-47.

PMID:
10512357
19.
20.

Naturally processed T cell epitopes from human glutamic acid decarboxylase identified using mice transgenic for the type 1 diabetes-associated human MHC class II allele, DRB1*0401.

Wicker LS, Chen SL, Nepom GT, Elliott JF, Freed DC, Bansal A, Zheng S, Herman A, Lernmark A, Zaller DM, Peterson LB, Rothbard JB, Cummings R, Whiteley PJ.

J Clin Invest. 1996 Dec 1;98(11):2597-603.

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