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Items: 1 to 20 of 102

1.

Design, synthesis, and antibacterial activities of conformationally constrained kanamycin A derivatives.

Zhang W, Chen Y, Liang Q, Li H, Jin H, Zhang L, Meng X, Li Z.

J Org Chem. 2013 Jan 18;78(2):400-9. doi: 10.1021/jo302247x. Epub 2012 Dec 18.

PMID:
23228010
2.

Glycodiversification for the optimization of the kanamycin class aminoglycosides.

Wang J, Li J, Chen HN, Chang H, Tanifum CT, Liu HH, Czyryca PG, Chang CW.

J Med Chem. 2005 Oct 6;48(20):6271-85.

PMID:
16190754
3.

Application of glycodiversification: expedient synthesis and antibacterial evaluation of a library of kanamycin B analogues.

Li J, Wang J, Czyryca PG, Chang H, Orsak TW, Evanson R, Chang CW.

Org Lett. 2004 Apr 29;6(9):1381-4.

PMID:
15101747
4.

Structure-activity relationships among the kanamycin aminoglycosides: role of ring I hydroxyl and amino groups.

Salian S, Matt T, Akbergenov R, Harish S, Meyer M, Duscha S, Shcherbakov D, Bernet BB, Vasella A, Westhof E, Böttger EC.

Antimicrob Agents Chemother. 2012 Dec;56(12):6104-8. doi: 10.1128/AAC.01326-12. Epub 2012 Sep 4.

5.

Synthesis and antibacterial activities of 1-N [(S)-omega-amino-2-hydroxyalkyl] kanamycin A derivatives.

Richardson K, Jevons S, Moore JW, Ross BC, Wright JR.

J Antibiot (Tokyo). 1977 Oct;30(10):843-6.

6.

New derivatives of kanamycin B obtained by modifications and substitutions in position 6". 1. Synthesis and microbiological evaluation.

Van Schepdael A, Delcourt J, Mulier M, Busson R, Verbist L, Vanderhaeghe HJ, Mingeot-Leclercq MP, Tulkens PM, Claes PJ.

J Med Chem. 1991 Apr;34(4):1468-75.

PMID:
2016724
7.

Aminoglycoside antibiotics. 3. Epimino derivatives of neamine, ribostamycin, and kanamycin B.

Kumar V, Jones GS Jr, Blacksberg I, Remers WA, Misiek M, Pursiano TA.

J Med Chem. 1980 Jan;23(1):42-9.

PMID:
6244410
8.

Selective modification of the 3''-amino group of kanamycin prevents significant loss of activity in resistant bacterial strains.

Santana AG, Zárate SG, Asensio JL, Revuelta J, Bastida A.

Org Biomol Chem. 2016 Jan 14;14(2):516-525. doi: 10.1039/c5ob01599e.

PMID:
26501183
9.

Evaluation of amphiphilic aminoglycoside-peptide triazole conjugates as antibacterial agents.

Bera S, Zhanel GG, Schweizer F.

Bioorg Med Chem Lett. 2010 May 15;20(10):3031-5. doi: 10.1016/j.bmcl.2010.03.116. Epub 2010 Apr 3.

PMID:
20413307
10.

Synthesis and Bioactivities of Kanamycin B-Derived Cationic Amphiphiles.

Fosso MY, Shrestha SK, Green KD, Garneau-Tsodikova S.

J Med Chem. 2015 Dec 10;58(23):9124-32. doi: 10.1021/acs.jmedchem.5b01375. Epub 2015 Dec 1.

11.

Synthesis of 4'-deoxy-4'-fluorokanamycin A and B.

Takahashi Y, Tsuneda S, Tsuchiya T, Koyama Y, Umezawa S.

Carbohydr Res. 1992 Jul 20;232(1):89-105.

PMID:
1423353
12.

Design, synthesis and antibacterial activity of a novel alkylide: 3-O-(3-aryl-propenyl)clarithromycin derivatives.

Liang JH, Wang YY, Zhu DY, Dong LJ, An MM, Wang R, Yao GW.

J Antibiot (Tokyo). 2009 Nov;62(11):605-11. doi: 10.1038/ja.2009.89. Epub 2009 Aug 28.

PMID:
19713989
13.
14.

Inhibitors of aminoglycoside resistance activated in cells.

Vong K, Tam IS, Yan X, Auclair K.

ACS Chem Biol. 2012 Mar 16;7(3):470-5. doi: 10.1021/cb200366u. Epub 2012 Jan 18.

15.
16.

Antibacterial activity of guanidinylated neomycin B- and kanamycin A-derived amphiphilic lipid conjugates.

Bera S, Zhanel GG, Schweizer F.

J Antimicrob Chemother. 2010 Jun;65(6):1224-7. doi: 10.1093/jac/dkq083. Epub 2010 Mar 23.

PMID:
20332193
17.

Aminoglycoside antibiotics. 2. N,N-Dialkylkanamycins.

Kumar V, Remers WA.

J Med Chem. 1979 Apr;22(4):432-6.

PMID:
107311
18.

A convenient synthetic pathway for multivalent assembly of aminoglycoside antibiotics starting from amikacin.

Tanaka H, Nishida Y, Furuta Y, Kobayashi K.

Bioorg Med Chem Lett. 2002 Jul 8;12(13):1723-6.

PMID:
12067546
19.

Aminoglycoside antibiotics. XII. Effect of N-alkylation in kanamycin antibiotics.

Nakagawa S, Toda S, Abe Y, Yamashita H, Fujisawa KI, Naito T, Kawaguchi H.

J Antibiot (Tokyo). 1978 Jul;31(7):675-80.

20.

New derivatives of kanamycin B obtained by modifications and substitutions in position 6''. 2. In vitro and computer-aided toxicological evaluation with respect to interactions with phosphatidylinositol.

Mingeot-Leclercq MP, Van Schepdael A, Brasseur R, Busson R, Vanderhaeghe HJ, Claes PJ, Tulkens PM.

J Med Chem. 1991 Apr;34(4):1476-82.

PMID:
2016725

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