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Items: 1 to 20 of 86

1.

Identification of DNA-dependent protein kinase catalytic subunit (DNA-PKcs) as a novel target of bisphenol A.

Ito Y, Ito T, Karasawa S, Enomoto T, Nashimoto A, Hase Y, Sakamoto S, Mimori T, Matsumoto Y, Yamaguchi Y, Handa H.

PLoS One. 2012;7(12):e50481. doi: 10.1371/journal.pone.0050481. Epub 2012 Dec 5.

2.

Inhibition of the DNA-dependent protein kinase catalytic subunit radiosensitizes malignant glioma cells by inducing autophagy.

Daido S, Yamamoto A, Fujiwara K, Sawaya R, Kondo S, Kondo Y.

Cancer Res. 2005 May 15;65(10):4368-75.

3.
4.

Regulation of DNA-dependent protein kinase by protein kinase CK2 in human glioblastoma cells.

Olsen BB, Issinger OG, Guerra B.

Oncogene. 2010 Nov 11;29(45):6016-26. doi: 10.1038/onc.2010.337. Epub 2010 Aug 16.

PMID:
20711232
5.

DNA-PKcs-dependent modulation of cellular radiosensitivity by a selective cyclooxygenase-2 inhibitor.

Kodym E, Kodym R, Chen BP, Chen DJ, Morotomi-Yano K, Choy H, Saha D.

Int J Radiat Oncol Biol Phys. 2007 Sep 1;69(1):187-93.

PMID:
17707272
6.

Restoration of T cell-specific V(D)J recombination in DNA-PKcs(-/-) mice by ionizing radiation: The effects on survival, development, and tumorigenesis.

Li XL, Shen SR, Wang S, Ouyang HH, Li GC.

Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai). 2002 Mar;34(2):149-57.

7.
8.

A role of DNA-dependent protein kinase for the activation of AMP-activated protein kinase in response to glucose deprivation.

Amatya PN, Kim HB, Park SJ, Youn CK, Hyun JW, Chang IY, Lee JH, You HJ.

Biochim Biophys Acta. 2012 Dec;1823(12):2099-108. doi: 10.1016/j.bbamcr.2012.08.022. Epub 2012 Sep 7.

9.

[Role of DNA-dependent protein kinase catalytic subunit in silica-induced DNA double-strand break repair in human embryo lung fibroblasts].

Zhang FM, Liu BC, Liu HF, Jia XW, Ye M.

Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2009 Jan;27(1):2-6. Chinese.

PMID:
19224683
10.
11.

Partial deficiency of DNA-PKcs increases ionizing radiation-induced mutagenesis and telomere instability in human cells.

Zhang Y, Zhou J, Cao X, Zhang Q, Lim CU, Ullrich RL, Bailey SM, Liber HL.

Cancer Lett. 2007 May 18;250(1):63-73. Epub 2006 Nov 13.

PMID:
17095151
12.

NK314 potentiates antitumor activity with adult T-cell leukemia-lymphoma cells by inhibition of dual targets on topoisomerase II{alpha} and DNA-dependent protein kinase.

Hisatomi T, Sueoka-Aragane N, Sato A, Tomimasu R, Ide M, Kurimasa A, Okamoto K, Kimura S, Sueoka E.

Blood. 2011 Mar 31;117(13):3575-84. doi: 10.1182/blood-2010-02-270439. Epub 2011 Jan 18.

13.

DNA-PKcs inhibition sensitizes cancer cells to carbon-ion irradiation via telomere capping disruption.

Zhou X, Zhang X, Xie Y, Tanaka K, Wang B, Zhang H.

PLoS One. 2013 Aug 27;8(8):e72641. doi: 10.1371/journal.pone.0072641. eCollection 2013.

14.

Protein phosphatase 6 interacts with the DNA-dependent protein kinase catalytic subunit and dephosphorylates gamma-H2AX.

Douglas P, Zhong J, Ye R, Moorhead GB, Xu X, Lees-Miller SP.

Mol Cell Biol. 2010 Mar;30(6):1368-81. doi: 10.1128/MCB.00741-09. Epub 2010 Jan 11.

15.

DNA-dependent protein kinase catalytic subunit modulates the stability of c-Myc oncoprotein.

An J, Yang DY, Xu QZ, Zhang SM, Huo YY, Shang ZF, Wang Y, Wu DC, Zhou PK.

Mol Cancer. 2008 Apr 22;7:32. doi: 10.1186/1476-4598-7-32.

16.

DNA-PK phosphorylates histone H2AX during apoptotic DNA fragmentation in mammalian cells.

Mukherjee B, Kessinger C, Kobayashi J, Chen BP, Chen DJ, Chatterjee A, Burma S.

DNA Repair (Amst). 2006 May 10;5(5):575-90. Epub 2006 Mar 29.

PMID:
16567133
17.

Inactivation of DNA-dependent protein kinase promotes heat-induced apoptosis independently of heat-shock protein induction in human cancer cell lines.

Okazawa S, Furusawa Y, Kariya A, Hassan MA, Arai M, Hayashi R, Tabuchi Y, Kondo T, Tobe K.

PLoS One. 2013;8(3):e58325. doi: 10.1371/journal.pone.0058325. Epub 2013 Mar 11.

18.

Akt promotes post-irradiation survival of human tumor cells through initiation, progression, and termination of DNA-PKcs-dependent DNA double-strand break repair.

Toulany M, Lee KJ, Fattah KR, Lin YF, Fehrenbacher B, Schaller M, Chen BP, Chen DJ, Rodemann HP.

Mol Cancer Res. 2012 Jul;10(7):945-57. doi: 10.1158/1541-7786.MCR-11-0592. Epub 2012 May 17.

19.

Inactivation of DNA-dependent protein kinase leads to spindle disruption and mitotic catastrophe with attenuated checkpoint protein 2 Phosphorylation in response to DNA damage.

Shang ZF, Huang B, Xu QZ, Zhang SM, Fan R, Liu XD, Wang Y, Zhou PK.

Cancer Res. 2010 May 1;70(9):3657-66. doi: 10.1158/0008-5472.CAN-09-3362. Epub 2010 Apr 20.

20.

DNA-dependent protein kinase is a therapeutic target and an indicator of poor prognosis in B-cell chronic lymphocytic leukemia.

Willmore E, Elliott SL, Mainou-Fowler T, Summerfield GP, Jackson GH, O'Neill F, Lowe C, Carter A, Harris R, Pettitt AR, Cano-Soumillac C, Griffin RJ, Cowell IG, Austin CA, Durkacz BW.

Clin Cancer Res. 2008 Jun 15;14(12):3984-92. doi: 10.1158/1078-0432.CCR-07-5158.

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