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Items: 1 to 20 of 136

1.

Genetic loss of murine pyrin, the Familial Mediterranean Fever protein, increases interleukin-1β levels.

Hesker PR, Nguyen M, Kovarova M, Ting JP, Koller BH.

PLoS One. 2012;7(11):e51105. doi: 10.1371/journal.pone.0051105. Epub 2012 Nov 30.

2.

Dysregulated production of interleukin-1β upon activation of the NLRP3 inflammasome in patients with familial Mediterranean fever.

Repa A, Bertsias GK, Petraki E, Choulaki C, Vassou D, Kambas K, Boumpas DT, Goulielmos G, Sidiropoulos P.

Hum Immunol. 2015 Jul;76(7):488-95. doi: 10.1016/j.humimm.2015.06.007. Epub 2015 Jun 12.

PMID:
26074413
3.

Increased NLRP3-dependent interleukin 1β secretion in patients with familial Mediterranean fever: correlation with MEFV genotype.

Omenetti A, Carta S, Delfino L, Martini A, Gattorno M, Rubartelli A.

Ann Rheum Dis. 2014 Feb;73(2):462-9. doi: 10.1136/annrheumdis-2012-202774. Epub 2013 Mar 16.

PMID:
23505242
4.

Advances in the understanding of familial Mediterranean fever and possibilities for targeted therapy.

Chae JJ, Aksentijevich I, Kastner DL.

Br J Haematol. 2009 Sep;146(5):467-78. doi: 10.1111/j.1365-2141.2009.07733.x. Epub 2009 May 14. Review.

5.

Unified Modeling of Familial Mediterranean Fever and Cryopyrin Associated Periodic Syndromes.

Bozkurt Y, Demir A, Erman B, Gül A.

Comput Math Methods Med. 2015;2015:893507. doi: 10.1155/2015/893507. Epub 2015 May 28.

6.

Critical role of ASC inflammasomes and bacterial type IV secretion system in caspase-1 activation and host innate resistance to Brucella abortus infection.

Gomes MT, Campos PC, Oliveira FS, Corsetti PP, Bortoluci KR, Cunha LD, Zamboni DS, Oliveira SC.

J Immunol. 2013 Apr 1;190(7):3629-38. doi: 10.4049/jimmunol.1202817. Epub 2013 Mar 4.

8.

The NLRP3 inflammasome is up-regulated in cardiac fibroblasts and mediates myocardial ischaemia-reperfusion injury.

Sandanger Ø, Ranheim T, Vinge LE, Bliksøen M, Alfsnes K, Finsen AV, Dahl CP, Askevold ET, Florholmen G, Christensen G, Fitzgerald KA, Lien E, Valen G, Espevik T, Aukrust P, Yndestad A.

Cardiovasc Res. 2013 Jul 1;99(1):164-74. doi: 10.1093/cvr/cvt091. Epub 2013 Apr 10.

PMID:
23580606
9.

Gain-of-function Pyrin mutations induce NLRP3 protein-independent interleukin-1β activation and severe autoinflammation in mice.

Chae JJ, Cho YH, Lee GS, Cheng J, Liu PP, Feigenbaum L, Katz SI, Kastner DL.

Immunity. 2011 May 27;34(5):755-68. doi: 10.1016/j.immuni.2011.02.020. Epub 2011 May 19.

10.

Caspase-4 is required for activation of inflammasomes.

Sollberger G, Strittmatter GE, Kistowska M, French LE, Beer HD.

J Immunol. 2012 Feb 15;188(4):1992-2000. doi: 10.4049/jimmunol.1101620. Epub 2012 Jan 13.

11.

Lipopolysaccharide/adenosine triphosphate induces IL‑1β and IL-18 secretion through the NLRP3 inflammasome in RAW264.7 murine macrophage cells.

Xie Q, Shen WW, Zhong J, Huang C, Zhang L, Li J.

Int J Mol Med. 2014 Jul;34(1):341-9. doi: 10.3892/ijmm.2014.1755. Epub 2014 Apr 24.

PMID:
24789624
12.

Involvement of the AIM2, NLRC4, and NLRP3 inflammasomes in caspase-1 activation by Listeria monocytogenes.

Wu J, Fernandes-Alnemri T, Alnemri ES.

J Clin Immunol. 2010 Sep;30(5):693-702. doi: 10.1007/s10875-010-9425-2. Epub 2010 May 20.

13.

Defect of suppression of inflammasome-independent interleukin-8 secretion from SW982 synovial sarcoma cells by familial Mediterranean fever-derived pyrin mutations.

Sugiyama R, Agematsu K, Migita K, Nakayama J, Mokuda S, Ogura F, Haraikawa K, Okumura C, Suehiro S, Morikawa S, Ito Y, Masumoto J.

Mol Biol Rep. 2014 Jan;41(1):545-53. doi: 10.1007/s11033-013-2890-y. Epub 2013 Dec 7.

PMID:
24318677
14.

The SPRY domain of Pyrin, mutated in familial Mediterranean fever patients, interacts with inflammasome components and inhibits proIL-1beta processing.

Papin S, Cuenin S, Agostini L, Martinon F, Werner S, Beer HD, Grütter C, Grütter M, Tschopp J.

Cell Death Differ. 2007 Aug;14(8):1457-66. Epub 2007 Apr 13.

15.

A Yersinia effector with enhanced inhibitory activity on the NF-κB pathway activates the NLRP3/ASC/caspase-1 inflammasome in macrophages.

Zheng Y, Lilo S, Brodsky IE, Zhang Y, Medzhitov R, Marcu KB, Bliska JB.

PLoS Pathog. 2011 Apr;7(4):e1002026. doi: 10.1371/journal.ppat.1002026. Epub 2011 Apr 21.

16.

Tumor suppressor death-associated protein kinase is required for full IL-1β production.

Chuang YT, Lin YC, Lin KH, Chou TF, Kuo WC, Yang KT, Wu PR, Chen RH, Kimchi A, Lai MZ.

Blood. 2011 Jan 20;117(3):960-70. doi: 10.1182/blood-2010-08-303115. Epub 2010 Nov 1.

17.

The B30.2 domain of pyrin, the familial Mediterranean fever protein, interacts directly with caspase-1 to modulate IL-1beta production.

Chae JJ, Wood G, Masters SL, Richard K, Park G, Smith BJ, Kastner DL.

Proc Natl Acad Sci U S A. 2006 Jun 27;103(26):9982-7. Epub 2006 Jun 19.

18.

The purinergic 2X7 receptor participates in renal inflammation and injury induced by high-fat diet: possible role of NLRP3 inflammasome activation.

Solini A, Menini S, Rossi C, Ricci C, Santini E, Blasetti Fantauzzi C, Iacobini C, Pugliese G.

J Pathol. 2013 Nov;231(3):342-53. doi: 10.1002/path.4237. Epub 2013 Sep 3.

PMID:
23843215
19.

Inflammasome activation causes dual recruitment of NLRC4 and NLRP3 to the same macromolecular complex.

Man SM, Hopkins LJ, Nugent E, Cox S, Glück IM, Tourlomousis P, Wright JA, Cicuta P, Monie TP, Bryant CE.

Proc Natl Acad Sci U S A. 2014 May 20;111(20):7403-8. doi: 10.1073/pnas.1402911111. Epub 2014 May 6.

20.

Pyrin levels in human monocytes and monocyte-derived macrophages regulate IL-1beta processing and release.

Seshadri S, Duncan MD, Hart JM, Gavrilin MA, Wewers MD.

J Immunol. 2007 Jul 15;179(2):1274-81.

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