Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 92

1.

Identification of the molecular mechanisms underlying the cytotoxic action of a potent platinum metallointercalator.

Wang S, Higgins VJ, Aldrich-Wright JR, Wu MJ.

J Chem Biol. 2012 Apr;5(2):51-61. doi: 10.1007/s12154-011-0070-x. Epub 2011 Dec 6.

2.

Comparative analyses of cytotoxicity and molecular mechanisms between platinum metallointercalators and cisplatin.

Wang S, Wu MJ, Higgins VJ, Aldrich-Wright JR.

Metallomics. 2012 Aug;4(9):950-9. doi: 10.1039/c2mt20102j.

PMID:
22814756
3.

Does cytotoxicity of metallointercalators correlate with cellular uptake or DNA affinity?

Davis KJ, Carrall JA, Lai B, Aldrich-Wright JR, Ralph SF, Dillon CT.

Dalton Trans. 2012 Aug 21;41(31):9417-26. doi: 10.1039/c2dt30217a. Epub 2012 Jun 28.

PMID:
22740039
4.

A Systems Biology Approach to Understanding the Mechanisms of Action of an Alternative Anticancer Compound in Comparison to Cisplatin.

Wright EP, Padula MP, Higgins VJ, Aldrich-Wright JR, Coorssen JR.

Proteomes. 2014 Nov 10;2(4):501-526. doi: 10.3390/proteomes2040501.

5.

Discrepancy between in vitro and in vivo antitumor effect of a new platinum(II) metallointercalator.

Moretto J, Chauffert B, Ghiringhelli F, Aldrich-Wright JR, Bouyer F.

Invest New Drugs. 2011 Dec;29(6):1164-76. doi: 10.1007/s10637-010-9461-z. Epub 2010 Jun 10.

PMID:
20535526
6.

The effects of 56MESS on mitochondrial and cytoskeletal proteins and the cell cycle in MDCK cells.

Garbutcheon-Singh KB, Myers S, Harper BW, Ng NS, Dong Q, Xie C, Aldrich-Wright JR.

Metallomics. 2013 Aug;5(8):1061-7. doi: 10.1039/c3mt00023k.

PMID:
23784536
7.

The effect of ancillary ligand chirality and phenanthroline functional group substitution on the cytotoxicity of platinum(II)-based metallointercalators.

Kemp S, Wheate NJ, Buck DP, Nikac M, Collins JG, Aldrich-Wright JR.

J Inorg Biochem. 2007 Jul;101(7):1049-58. Epub 2007 May 4.

PMID:
17544512
8.

Substituted beta-cyclodextrin and calix[4]arene as encapsulatory vehicles for platinum(II)-based DNA intercalators.

Krause-Heuer AM, Wheate NJ, Tilby MJ, Pearson DG, Ottley CJ, Aldrich-Wright JR.

Inorg Chem. 2008 Aug 4;47(15):6880-8. doi: 10.1021/ic800467c. Epub 2008 Jul 2.

PMID:
18597414
9.

Degradation of bidentate-coordinated platinum(II)-based DNA intercalators by reduced L-glutathione.

Kemp S, Wheate NJ, Pisani MJ, Aldrich-Wright JR.

J Med Chem. 2008 May 8;51(9):2787-94. doi: 10.1021/jm7016072. Epub 2008 Apr 16.

PMID:
18412325
10.

The antimicrobial properties of some copper(II) and platinum(II) 1,10-phenanthroline complexes.

Ng NS, Leverett P, Hibbs DE, Yang Q, Bulanadi JC, Wu MJ, Aldrich-Wright JR.

Dalton Trans. 2013 Mar 7;42(9):3196-209. doi: 10.1039/c2dt32392c. Epub 2012 Dec 11. Erratum in: Dalton Trans. 2013 Nov 19;42(48):16972.

PMID:
23233164
11.

Non-DNA-binding platinum anticancer agents: Cytotoxic activities of platinum-phosphato complexes towards human ovarian cancer cells.

Bose RN, Maurmann L, Mishur RJ, Yasui L, Gupta S, Grayburn WS, Hofstetter H, Salley T.

Proc Natl Acad Sci U S A. 2008 Nov 25;105(47):18314-9. doi: 10.1073/pnas.0803094105. Epub 2008 Nov 19. Erratum in: Proc Natl Acad Sci U S A. 2009 Jan 27;106(4):1292. Milton, Tara [corrected to Salley, Tara].

12.

Picoplatin overcomes resistance to cell toxicity in small-cell lung cancer cells previously treated with cisplatin and carboplatin.

Tang CH, Parham C, Shocron E, McMahon G, Patel N.

Cancer Chemother Pharmacol. 2011 Jun;67(6):1389-400. doi: 10.1007/s00280-010-1435-5. Epub 2010 Aug 31.

13.

Studies of the mechanism of action of platinum(II) complexes with potent cytotoxicity in human cancer cells.

Krause-Heuer AM, Grünert R, Kühne S, Buczkowska M, Wheate NJ, Le Pevelen DD, Boag LR, Fisher DM, Kasparkova J, Malina J, Bednarski PJ, Brabec V, Aldrich-Wright JR.

J Med Chem. 2009 Sep 10;52(17):5474-84. doi: 10.1021/jm9007104.

PMID:
19658404
15.

Establishment and characterization of an in vitro model of acquired resistance to cisplatin in a human testicular nonseminomatous germ cell line.

Kelland LR, Mistry P, Abel G, Freidlos F, Loh SY, Roberts JJ, Harrap KR.

Cancer Res. 1992 Apr 1;52(7):1710-6.

17.

The copper transporter CTR1 regulates cisplatin uptake in Saccharomyces cerevisiae.

Lin X, Okuda T, Holzer A, Howell SB.

Mol Pharmacol. 2002 Nov;62(5):1154-9. Erratum in: Mol Pharmacol. 2003 Apr;63(4):957.

19.

Chiral platinum(II) metallointercalators with potent in vitro cytotoxic activity.

Fisher DM, Bednarski PJ, Grünert R, Turner P, Fenton RR, Aldrich-Wright JR.

ChemMedChem. 2007 Apr;2(4):488-95.

PMID:
17340669
20.

Supplemental Content

Support Center