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Items: 1 to 20 of 70

1.

Systematic investigation of protein-small molecule interactions.

Li X, Wang X, Snyder M.

IUBMB Life. 2013 Jan;65(1):2-8. doi: 10.1002/iub.1111. Epub 2012 Dec 7. Review.

3.

Stabilization and inhibition of protein-protein interactions: the 14-3-3 case study.

Milroy LG, Brunsveld L, Ottmann C.

ACS Chem Biol. 2013 Jan 18;8(1):27-35. doi: 10.1021/cb300599t. Epub 2012 Dec 14. Review.

PMID:
23210482
4.

Developing therapeutic proteins by engineering ligand-receptor interactions.

Jones DS, Silverman AP, Cochran JR.

Trends Biotechnol. 2008 Sep;26(9):498-505. doi: 10.1016/j.tibtech.2008.05.009. Epub 2008 Jul 31. Review.

PMID:
18675482
5.

Protein-protein interactions as targets for small-molecule therapeutics in cancer.

White AW, Westwell AD, Brahemi G.

Expert Rev Mol Med. 2008 Mar 19;10:e8. doi: 10.1017/S1462399408000641. Review.

PMID:
18353193
6.

Regulatory roles of metabolites in cell signaling networks.

Li F, Xu W, Zhao S.

J Genet Genomics. 2013 Jul 20;40(7):367-74. doi: 10.1016/j.jgg.2013.05.002. Epub 2013 May 31. Review.

PMID:
23876777
7.

Revealing the allosterome: systematic identification of metabolite-protein interactions.

Orsak T, Smith TL, Eckert D, Lindsley JE, Borges CR, Rutter J.

Biochemistry. 2012 Jan 10;51(1):225-32. doi: 10.1021/bi201313s. Epub 2011 Dec 9.

PMID:
22122470
8.

Autoinhibited proteins as promising drug targets.

Peterson JR, Golemis EA.

J Cell Biochem. 2004 Sep 1;93(1):68-73. Review.

PMID:
15352163
9.

Recent progress in biomolecular engineering.

Ryu DD, Nam DH.

Biotechnol Prog. 2000 Jan-Feb;16(1):2-16. Review.

PMID:
10662483
11.

Modulation of protein-protein interactions with small organic molecules.

Berg T.

Angew Chem Int Ed Engl. 2003 Jun 6;42(22):2462-81. Review.

PMID:
12800163
12.

Protein phosphorylation and signal transduction modulation: chemistry perspectives for small-molecule drug discovery.

Sawyer TK, Shakespeare WC, Wang Y, Sundaramoorthi R, Huang WS, Metcalf CA 3rd, Thomas M, Lawrence BM, Rozamus L, Noehre J, Zhu X, Narula S, Bohacek RS, Weigele M, Dalgarno DC.

Med Chem. 2005 May;1(3):293-319. Review.

PMID:
16787325
13.

The role of small molecule inhibitors for veterinary patients.

London CA.

Vet Clin North Am Small Anim Pract. 2007 Nov;37(6):1121-36; vii. Review.

PMID:
17950886
14.

Exploiting bioorthogonal chemistry to elucidate protein-lipid binding interactions and other biological roles of phospholipids.

Best MD, Rowland MM, Bostic HE.

Acc Chem Res. 2011 Sep 20;44(9):686-98. doi: 10.1021/ar200060y. Epub 2011 May 6.

PMID:
21548554
15.

Protein-protein interactions as druggable targets: recent technological advances.

Higueruelo AP, Jubb H, Blundell TL.

Curr Opin Pharmacol. 2013 Oct;13(5):791-6. doi: 10.1016/j.coph.2013.05.009. Epub 2013 Jun 1. Review.

PMID:
23735579
16.

Consideration of allosterism and interacting proteins in the physiological functions of the serotonin transporter.

Zhong H, Sánchez C, Caron MG.

Biochem Pharmacol. 2012 Feb 15;83(4):435-42. doi: 10.1016/j.bcp.2011.09.020. Epub 2011 Oct 1. Review.

PMID:
21983034
17.

A computational analysis of protein interactions in metabolic networks reveals novel enzyme pairs potentially involved in metabolic channeling.

Huthmacher C, Gille C, Holzhütter HG.

J Theor Biol. 2008 Jun 7;252(3):456-64. Epub 2007 Oct 5.

PMID:
17988690
18.

A possible role for long non-coding RNA in modulating signaling pathways.

Rotblat B, Leprivier G, Sorensen PH.

Med Hypotheses. 2011 Dec;77(6):962-5. doi: 10.1016/j.mehy.2011.08.020. Epub 2011 Sep 7.

PMID:
21903344
19.

Human cancer protein-protein interaction network: a structural perspective.

Kar G, Gursoy A, Keskin O.

PLoS Comput Biol. 2009 Dec;5(12):e1000601. doi: 10.1371/journal.pcbi.1000601. Epub 2009 Dec 11.

20.

Protein-protein interactions: principles, techniques, and their potential role in new drug development.

Khan SH, Ahmad F, Ahmad N, Flynn DC, Kumar R.

J Biomol Struct Dyn. 2011 Jun;28(6):929-38. Review.

PMID:
21469753

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