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Items: 1 to 20 of 106

1.

Jozimine A2: the first dimeric Dioncophyllaceae-type naphthylisoquinoline alkaloid, with three chiral axes and high antiplasmodial activity.

Bringmann G, Zhang G, Büttner T, Bauckmann G, Kupfer T, Braunschweig H, Brun R, Mudogo V.

Chemistry. 2013 Jan 14;19(3):916-23. doi: 10.1002/chem.201202755. Epub 2012 Dec 5.

PMID:
23225585
2.

ent-Dioncophylleine A and related dehydrogenated naphthylisoquinoline alkaloids, the first Asian dioncophyllaceae-type alkaloids, from the "new"plant species Ancistrocladus benomensis.

Bringmann G, Dreyer M, Kopff H, Rischer H, Wohlfarth M, Hadi HA, Brun R, Meimberg H, Heubl G.

J Nat Prod. 2005 May;68(5):686-90.

PMID:
15921410
3.

Ancistrolikokine D, a 5,8'-coupled naphthylisoquinoline alkaloid, and related natural products from Ancistrocladus likoko.

Bringmann G, Saeb W, Rückert M, Mies J, Michel M, Mudogo V, Brun R.

Phytochemistry. 2003 Feb;62(4):631-6.

PMID:
12560038
4.

Ancistrocongolines A-D, new naphthylisoquinoline alkaloids from ancistrocladus congolensis.

Bringmann G, Messer K, Brun R, Mudogo V.

J Nat Prod. 2002 Aug;65(8):1096-101.

PMID:
12193010
5.

Shuangancistrotectorines A-E, dimeric naphthylisoquinoline alkaloids with three chiral biaryl axes from the Chinese plant Ancistrocladus tectorius.

Xu M, Bruhn T, Hertlein B, Brun R, Stich A, Wu J, Bringmann G.

Chemistry. 2010 Apr 12;16(14):4206-16. doi: 10.1002/chem.200903247.

PMID:
20235249
6.

Mbandakamines A and B, unsymmetrically coupled dimeric naphthylisoquinoline alkaloids, from a Congolese Ancistrocladus species.

Bringmann G, Lombe BK, Steinert C, Ioset KN, Brun R, Turini F, Heubl G, Mudogo V.

Org Lett. 2013 Jun 7;15(11):2590-3. doi: 10.1021/ol4005883. Epub 2013 May 13.

PMID:
23672531
7.

Ancistrotanzanine A, the first 5,3'-coupled naphthylisoquinoline alkaloid, and two further, 5,8'-linked related compounds from the newly described species Ancistrocladus tanzaniensis.

Bringmann G, Dreyer M, Faber JH, Dalsgaard PW, Staerk D, Jaroszewski JW, Ndangalasi H, Mbago F, Brun R, Reichert M, Maksimenka K, Christensen SB.

J Nat Prod. 2003 Sep;66(9):1159-65.

PMID:
14510589
8.

Ancistrotanzanine C and related 5,1'- and 7,3'-coupled naphthylisoquinoline alkaloids from Ancistrocladus tanzaniensis.

Bringmann G, Dreyer M, Faber JH, Dalsgaard PW, Staerk D, Jaroszewski JW, Ndangalasi H, Mbago F, Brun R, Christensen SB.

J Nat Prod. 2004 May;67(5):743-8.

PMID:
15165131
9.

Highly selective antiplasmodial naphthylisoquinoline alkaloids from Ancistrocladus tectorius.

Bringmann G, Zhang G, Olschläger T, Stich A, Wu J, Chatterjee M, Brun R.

Phytochemistry. 2013 Jul;91:220-8. doi: 10.1016/j.phytochem.2012.02.017. Epub 2012 Mar 27.

PMID:
22459968
10.

Ancistrolikokines A-C: new 5,8'-coupled naphthylisoquinoline alkaloids from Ancistrocladus likoko.

Bringmann G, Günther C, Saeb W, Mies J, Wickramasinghe A, Mudogo V, Brun R.

J Nat Prod. 2000 Oct;63(10):1333-7.

PMID:
11076547
11.

Dioncophylline E from Dioncophyllum thollonii, the first 7,3'-coupled dioncophyllaceous naphthylisoquinoline alkaloid.

Bringmann G, Messer K, Wolf K, Mühlbacher J, Grüne M, Brun R, Louis AM.

Phytochemistry. 2002 Jun;60(4):389-97.

PMID:
12031431
12.

Ancistrobenomine a, the first naphthylisoquinoline oxygenated at Me-3, and related 5,1'-coupled alkaloids, from the "new" plant species ancistrocladusbenomensis.

Bringmann G, Dreyer M, Rischer H, Wolf K, Hadi HA, Brun R, Meimberg H, Heubl G.

J Nat Prod. 2004 Dec;67(12):2058-62.

PMID:
15620251
13.

Habropetaline A, an antimalarial naphthylisoquinoline alkaloid from Triphyophyllum peltatum.

Bringmann G, Messer K, Schwöbel B, Brun R, Aké Assi L.

Phytochemistry. 2003 Feb;62(3):345-9.

PMID:
12620347
14.

Korundamine A, a novel HIV-inhibitory and antimalarial "hybrid" naphthylisoquinoline alkaloid heterodimer from Ancistrocladus korupensis.

Hallock YF, Cardellina JH 2nd, Schäffer M, Bringmann G, François G, Boyd MR.

Bioorg Med Chem Lett. 1998 Jul 7;8(13):1729-34.

PMID:
9873424
15.

Highly antiplasmodial non-natural oxidative products of dioncophylline A: synthesis, absolute configuration, and conformational stability.

Hemberger Y, Zhang G, Brun R, Kaiser M, Bringmann G.

Chemistry. 2015 Oct 5;21(41):14507-18. doi: 10.1002/chem.201501657. Epub 2015 Aug 13.

PMID:
26272344
16.

Michellamines D-F, new HIV-inhibitory dimeric naphthylisoquinoline alkaloids, and korupensamine E, a new antimalarial monomer, from Ancistrocladus korupensis.

Hallock YF, Manfredi KP, Dai JR, Cardellina JH 2nd, Gulakowski RJ, McMahon JB, Schäffer M, Stahl M, Gulden KP, Bringmann G, François G, Boyd MR.

J Nat Prod. 1997 Jul;60(7):677-83.

PMID:
9249970
17.

Synthesis and pharmacological evaluation of fluorescent and photoactivatable analogues of antiplasmodial naphthylisoquinolines.

Bringmann G, Gampe CM, Reichert Y, Bruhn T, Faber JH, Mikyna M, Reichert M, Leippe M, Brun R, Gelhaus C.

J Med Chem. 2007 Nov 29;50(24):6104-15. Epub 2007 Nov 9.

PMID:
17990865
18.

Synthesis and antiprotozoal activities of dicationic bis(phenoxymethyl)benzenes, bis(phenoxymethyl)naphthalenes, and bis(benzyloxy)naphthalenes.

Patrick DA, Bakunov SA, Bakunova SM, Kumar EV, Chen H, Jones SK, Wenzler T, Barzcz T, Werbovetz KA, Brun R, Tidwell RR.

Eur J Med Chem. 2009 Sep;44(9):3543-51. doi: 10.1016/j.ejmech.2009.03.014. Epub 2009 Mar 24.

PMID:
19409677
19.

Synthesis and in vitro antiprotozoal activities of water-soluble, inexpensive 3,7-bis(dialkylamino)phenoxazin-5-ium derivatives.

Ge JF, Arai C, Kaiser M, Wittlin S, Brun R, Ihara M.

J Med Chem. 2008 Jun 26;51(12):3654-8. doi: 10.1021/jm8003619. Epub 2008 May 14.

PMID:
18476684
20.

N,N-dimethyldioncophyllinium A iodide: synthesis, stereoanalysis, and antimalarial activity of the first N-quaternary naphthylisoquinolinium salt.

Bringmann G, Ochse M, Schäffer M, God R, Walter R, François G.

Planta Med. 1997 Dec;63(6):544-7.

PMID:
9434607

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