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Items: 1 to 20 of 165

1.

Sub-toxic dose of apigenin sensitizes HepG2 cells to TRAIL through ERK-dependent up-regulation of TRAIL receptor DR5.

Kim EY, Yu JS, Yang M, Kim AK.

Mol Cells. 2013 Jan;35(1):32-40. doi: 10.1007/s10059-013-2175-2. Epub 2012 Dec 4.

2.

Gossypol induces death receptor-5 through activation of the ROS-ERK-CHOP pathway and sensitizes colon cancer cells to TRAIL.

Sung B, Ravindran J, Prasad S, Pandey MK, Aggarwal BB.

J Biol Chem. 2010 Nov 12;285(46):35418-27. doi: 10.1074/jbc.M110.172767. Epub 2010 Sep 13. Retraction in: Sung B, Ravindran J, Prasad S, Pandey MK, Aggarwal BB. J Biol Chem. 2016 Aug 5;291(32):16923.

3.

[Thioridazine Sensitizes Apoptotic Effect of TRAIL in Human Lung Cancer PC9 Cells Through ER Stress Mediated Up-regulation of DR5].

Li J, Wang Y, Liu L, Yuan Y, Bao Y.

Zhongguo Fei Ai Za Zhi. 2017 Feb 20;20(2):80-87. doi: 10.3779/j.issn.1009-3419.2017.02.02. Chinese.

4.
5.

Camptothecin sensitizes human hepatoma Hep3B cells to TRAIL-mediated apoptosis via ROS-dependent death receptor 5 upregulation with the involvement of MAPKs.

Jayasooriya RG, Choi YH, Hyun JW, Kim GY.

Environ Toxicol Pharmacol. 2014 Nov;38(3):959-67. doi: 10.1016/j.etap.2014.10.012. Epub 2014 Oct 24.

PMID:
25461556
6.

Seleno-cyclodextrin sensitises human breast cancer cells to TRAIL-induced apoptosis through DR5 induction and NF-κB suppression.

Lin T, Ding Z, Li N, Xu J, Luo G, Liu J, Shen J.

Eur J Cancer. 2011 Aug;47(12):1890-907. doi: 10.1016/j.ejca.2011.04.004. Epub 2011 May 10.

PMID:
21565489
7.

Apigenin sensitizes prostate cancer cells to Apo2L/TRAIL by targeting adenine nucleotide translocase-2.

Oishi M, Iizumi Y, Taniguchi T, Goi W, Miki T, Sakai T.

PLoS One. 2013;8(2):e55922. doi: 10.1371/journal.pone.0055922. Epub 2013 Feb 19.

8.

Activation of p38 MAPK by damnacanthal mediates apoptosis in SKHep 1 cells through the DR5/TRAIL and TNFR1/TNF-α and p53 pathways.

Lin FL, Hsu JL, Chou CH, Wu WJ, Chang CI, Liu HJ.

Eur J Pharmacol. 2011 Jan 10;650(1):120-9. doi: 10.1016/j.ejphar.2010.10.005. Epub 2010 Oct 14.

PMID:
20951126
9.

Pro-survival effects by NF-κB, Akt and ERK(1/2) and anti-apoptosis actions by Six1 disrupt apoptotic functions of TRAIL-Dr4/5 pathway in ovarian cancer.

Yang J, Li G, Zhang K.

Biomed Pharmacother. 2016 Dec;84:1078-1087. doi: 10.1016/j.biopha.2016.10.028. Epub 2016 Oct 22.

PMID:
27780136
10.

Rosiglitazone promotes tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by reactive oxygen species-mediated up-regulation of death receptor 5 and down-regulation of c-FLIP.

Kim YH, Jung EM, Lee TJ, Kim SH, Choi YH, Park JW, Park JW, Choi KS, Kwon TK.

Free Radic Biol Med. 2008 Mar 15;44(6):1055-68. doi: 10.1016/j.freeradbiomed.2007.12.001. Epub 2007 Dec 8.

PMID:
18164688
11.
13.

Down-regulation of Cbl-b by bufalin results in up-regulation of DR4/DR5 and sensitization of TRAIL-induced apoptosis in breast cancer cells.

Yan S, Qu X, Xu C, Zhu Z, Zhang L, Xu L, Song N, Teng Y, Liu Y.

J Cancer Res Clin Oncol. 2012 Aug;138(8):1279-89. doi: 10.1007/s00432-012-1204-4. Epub 2012 Mar 24.

PMID:
22447040
14.

Tanshinone IIA Facilitates TRAIL Sensitization by Up-regulating DR5 through the ROS-JNK-CHOP Signaling Axis in Human Ovarian Carcinoma Cell Lines.

Chang CC, Kuan CP, Lin JY, Lai JS, Ho TF.

Chem Res Toxicol. 2015 Aug 17;28(8):1574-83. doi: 10.1021/acs.chemrestox.5b00150. Epub 2015 Jul 31.

PMID:
26203587
15.

The dietary flavonoid apigenin sensitizes malignant tumor cells to tumor necrosis factor-related apoptosis-inducing ligand.

Horinaka M, Yoshida T, Shiraishi T, Nakata S, Wakada M, Sakai T.

Mol Cancer Ther. 2006 Apr;5(4):945-51.

16.

α-Hispanolol sensitizes hepatocellular carcinoma cells to TRAIL-induced apoptosis via death receptor up-regulation.

Mota A, Jiménez-Garcia L, Herránz S, de Las Heras B, Hortelano S.

Toxicol Appl Pharmacol. 2015 Aug 1;286(3):168-77. doi: 10.1016/j.taap.2015.04.012. Epub 2015 Apr 28.

PMID:
25930665
17.

Low-dose 5-fluorouracil sensitizes HepG2 cells to TRAIL through TRAIL receptor DR5 and survivin-dependent mechanisms.

Yang L, Wang Y, Zheng H, Zhang D, Wu X, Sun G, Yang T.

J Chemother. 2017 Jun;29(3):179-188. doi: 10.1080/1120009X.2016.1277048. Epub 2017 Jan 9.

PMID:
28067150
18.
19.

Piceatannol enhances TRAIL-induced apoptosis in human leukemia THP-1 cells through Sp1- and ERK-dependent DR5 up-regulation.

Kang CH, Moon DO, Choi YH, Choi IW, Moon SK, Kim WJ, Kim GY.

Toxicol In Vitro. 2011 Apr;25(3):605-12. doi: 10.1016/j.tiv.2010.12.006. Epub 2010 Dec 15.

PMID:
21167276
20.

The herbal compound cryptotanshinone restores sensitivity in cancer cells that are resistant to the tumor necrosis factor-related apoptosis-inducing ligand.

Tse AK, Chow KY, Cao HH, Cheng CY, Kwan HY, Yu H, Zhu GY, Wu YC, Fong WF, Yu ZL.

J Biol Chem. 2013 Oct 11;288(41):29923-33. doi: 10.1074/jbc.M113.483909. Epub 2013 Aug 28.

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