Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 111

1.

Amyloid-β induces hepatic insulin resistance in vivo via JAK2.

Zhang Y, Zhou B, Deng B, Zhang F, Wu J, Wang Y, Le Y, Zhai Q.

Diabetes. 2013 Apr;62(4):1159-66. doi: 10.2337/db12-0670. Epub 2012 Dec 6.

2.

Amyloid-β induces hepatic insulin resistance by activating JAK2/STAT3/SOCS-1 signaling pathway.

Zhang Y, Zhou B, Zhang F, Wu J, Hu Y, Liu Y, Zhai Q.

Diabetes. 2012 Jun;61(6):1434-43. doi: 10.2337/db11-0499. Epub 2012 Apr 20.

3.

Amyloid-beta causes memory impairment by disturbing the JAK2/STAT3 axis in hippocampal neurons.

Chiba T, Yamada M, Sasabe J, Terashita K, Shimoda M, Matsuoka M, Aiso S.

Mol Psychiatry. 2009 Feb;14(2):206-22. doi: 10.1038/mp.2008.105. Epub 2008 Sep 23.

PMID:
18813209
4.

Tyk2/STAT3 signaling mediates beta-amyloid-induced neuronal cell death: implications in Alzheimer's disease.

Wan J, Fu AK, Ip FC, Ng HK, Hugon J, Page G, Wang JH, Lai KO, Wu Z, Ip NY.

J Neurosci. 2010 May 19;30(20):6873-81. doi: 10.1523/JNEUROSCI.0519-10.2010.

5.

Hydroxy-safflor yellow A attenuates Aβ₁₋₄₂-induced inflammation by modulating the JAK2/STAT3/NF-κB pathway.

Zhang ZH, Yu LJ, Hui XC, Wu ZZ, Yin KL, Yang H, Xu Y.

Brain Res. 2014 May 14;1563:72-80. doi: 10.1016/j.brainres.2014.03.036. Epub 2014 Mar 29.

PMID:
24690200
6.

Constitutive STAT3 phosphorylation contributes to skeletal muscle insulin resistance in type 2 diabetes.

Mashili F, Chibalin AV, Krook A, Zierath JR.

Diabetes. 2013 Feb;62(2):457-65. doi: 10.2337/db12-0337. Epub 2012 Oct 5.

7.

Metformin ameliorates IL-6-induced hepatic insulin resistance via induction of orphan nuclear receptor small heterodimer partner (SHP) in mouse models.

Kim YD, Kim YH, Cho YM, Kim DK, Ahn SW, Lee JM, Chanda D, Shong M, Lee CH, Choi HS.

Diabetologia. 2012 May;55(5):1482-94. doi: 10.1007/s00125-012-2494-4. Epub 2012 Feb 21.

PMID:
22349108
8.

Aβ-induced microglial cell activation is inhibited by baicalin through the JAK2/STAT3 signaling pathway.

Xiong J, Wang C, Chen H, Hu Y, Tian L, Pan J, Geng M.

Int J Neurosci. 2014 Aug;124(8):609-20. doi: 10.3109/00207454.2013.865027. Epub 2013 Dec 12.

PMID:
24219385
9.

Helicobacter pylori infection causes hepatic insulin resistance by the c-Jun/miR-203/SOCS3 signaling pathway.

Zhou X, Liu W, Gu M, Zhou H, Zhang G.

J Gastroenterol. 2015 Oct;50(10):1027-40. doi: 10.1007/s00535-015-1051-6. Epub 2015 Feb 19.

PMID:
25689935
10.

The peroxisome proliferator-activated receptor (PPAR) β/δ agonist GW501516 inhibits IL-6-induced signal transducer and activator of transcription 3 (STAT3) activation and insulin resistance in human liver cells.

Serrano-Marco L, Barroso E, El Kochairi I, Palomer X, Michalik L, Wahli W, Vázquez-Carrera M.

Diabetologia. 2012 Mar;55(3):743-51. doi: 10.1007/s00125-011-2401-4. Epub 2011 Dec 17.

PMID:
22179221
11.
12.

Silencing of FGF-21 expression promotes hepatic gluconeogenesis and glycogenolysis by regulation of the STAT3-SOCS3 signal.

Wang C, Dai J, Yang M, Deng G, Xu S, Jia Y, Boden G, Ma ZA, Yang G, Li L.

FEBS J. 2014 May;281(9):2136-47. doi: 10.1111/febs.12767. Epub 2014 Apr 1.

13.

Increased Aβ production prompts the onset of glucose intolerance and insulin resistance.

Jiménez-Palomares M, Ramos-Rodríguez JJ, López-Acosta JF, Pacheco-Herrero M, Lechuga-Sancho AM, Perdomo G, García-Alloza M, Cózar-Castellano I.

Am J Physiol Endocrinol Metab. 2012 Jun 1;302(11):E1373-80. doi: 10.1152/ajpendo.00500.2011. Epub 2012 Mar 13.

14.

Hepatic Oncostatin M Receptor β Regulates Obesity-Induced Steatosis and Insulin Resistance.

Luo P, Wang PX, Li ZZ, Zhang XJ, Jiang X, Gong J, Qin JJ, Guo J, Zhu X, Yang S, Li H.

Am J Pathol. 2016 May;186(5):1278-92. doi: 10.1016/j.ajpath.2015.12.028. Epub 2016 Mar 11.

PMID:
26976243
15.

Hydrodynamic tail vein injection of SOCS3 eukaryotic expression vector in vivo promoted liver lipid metabolism and hepatocyte apoptosis in mouse.

Liu Z, Gan L, Yang X, Zhang Z, Sun C.

Biochem Cell Biol. 2014 Apr;92(2):119-25. doi: 10.1139/bcb-2013-0117. Epub 2014 Feb 19.

PMID:
24697696
16.

Histone deacetylases inhibitor sodium butyrate inhibits JAK2/STAT signaling through upregulation of SOCS1 and SOCS3 mediated by HDAC8 inhibition in myeloproliferative neoplasms.

Gao SM, Chen CQ, Wang LY, Hong LL, Wu JB, Dong PH, Yu FJ.

Exp Hematol. 2013 Mar;41(3):261-70.e4. doi: 10.1016/j.exphem.2012.10.012. Epub 2012 Oct 27.

PMID:
23111066
17.

Targeting the JAK2/STAT3 axis in Alzheimer's disease.

Chiba T, Yamada M, Aiso S.

Expert Opin Ther Targets. 2009 Oct;13(10):1155-67. doi: 10.1517/14728220903213426. Review.

PMID:
19663649
18.

Transcriptional activation of the suppressor of cytokine signaling-3 (SOCS-3) gene via STAT3 is increased in F9 REX1 (ZFP-42) knockout teratocarcinoma stem cells relative to wild-type cells.

Xu J, Sylvester R, Tighe AP, Chen S, Gudas LJ.

J Mol Biol. 2008 Mar 14;377(1):28-46. doi: 10.1016/j.jmb.2007.12.038. Epub 2008 Jan 30.

19.

Central role of suppressors of cytokine signaling proteins in hepatic steatosis, insulin resistance, and the metabolic syndrome in the mouse.

Ueki K, Kondo T, Tseng YH, Kahn CR.

Proc Natl Acad Sci U S A. 2004 Jul 13;101(28):10422-7. Epub 2004 Jul 6. Erratum in: Proc Natl Acad Sci U S A. 2005 Sep 20;102(38):13710.

20.

Molecular basis for the critical role of suppressor of cytokine signaling-1 in melanoma brain metastasis.

Huang FJ, Steeg PS, Price JE, Chiu WT, Chou PC, Xie K, Sawaya R, Huang S.

Cancer Res. 2008 Dec 1;68(23):9634-42. doi: 10.1158/0008-5472.CAN-08-1429.

Supplemental Content

Support Center