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Items: 1 to 20 of 121

1.

FMNL3 FH2-actin structure gives insight into formin-mediated actin nucleation and elongation.

Thompson ME, Heimsath EG, Gauvin TJ, Higgs HN, Kull FJ.

Nat Struct Mol Biol. 2013 Jan;20(1):111-8. doi: 10.1038/nsmb.2462. Epub 2012 Dec 9.

2.

The C terminus of formin FMNL3 accelerates actin polymerization and contains a WH2 domain-like sequence that binds both monomers and filament barbed ends.

Heimsath EG Jr, Higgs HN.

J Biol Chem. 2012 Jan 27;287(5):3087-98. doi: 10.1074/jbc.M111.312207. Epub 2011 Nov 17.

3.

Electrostatic interactions between the Bni1p Formin FH2 domain and actin influence actin filament nucleation.

Baker JL, Courtemanche N, Parton DL, McCullagh M, Pollard TD, Voth GA.

Structure. 2015 Jan 6;23(1):68-79. doi: 10.1016/j.str.2014.10.014. Epub 2014 Dec 4.

4.

Assembly of filopodia by the formin FRL2 (FMNL3).

Harris ES, Gauvin TJ, Heimsath EG, Higgs HN.

Cytoskeleton (Hoboken). 2010 Dec;67(12):755-72. doi: 10.1002/cm.20485. Epub 2010 Nov 2.

5.

Structural basis of actin filament nucleation and processive capping by a formin homology 2 domain.

Otomo T, Tomchick DR, Otomo C, Panchal SC, Machius M, Rosen MK.

Nature. 2005 Feb 3;433(7025):488-94. Epub 2005 Jan 5.

PMID:
15635372
6.

Structure of the FH2 domain of Daam1: implications for formin regulation of actin assembly.

Lu J, Meng W, Poy F, Maiti S, Goode BL, Eck MJ.

J Mol Biol. 2007 Jun 22;369(5):1258-69. Epub 2007 Apr 5.

7.

Crystal structure of a complex between amino and carboxy terminal fragments of mDia1: insights into autoinhibition of diaphanous-related formins.

Nezami A, Poy F, Toms A, Zheng W, Eck MJ.

PLoS One. 2010 Sep 30;5(9). pii: e12992. doi: 10.1371/journal.pone.0012992.

8.

The activities of the C-terminal regions of the formin protein disheveled-associated activator of morphogenesis (DAAM) in actin dynamics.

Vig AT, Földi I, Szikora S, Migh E, Gombos R, Tóth MÁ, Huber T, Pintér R, Talián GC, Mihály J, Bugyi B.

J Biol Chem. 2017 Aug 18;292(33):13566-13583. doi: 10.1074/jbc.M117.799247. Epub 2017 Jun 22.

PMID:
28642367
9.

Actin filament bundling and different nucleating effects of mouse Diaphanous-related formin FH2 domains on actin/ADF and actin/cofilin complexes.

Machaidze G, Sokoll A, Shimada A, Lustig A, Mazur A, Wittinghofer A, Aebi U, Mannherz HG.

J Mol Biol. 2010 Nov 5;403(4):529-45. doi: 10.1016/j.jmb.2010.09.017. Epub 2010 Oct 1.

PMID:
20869367
10.

The role of the FH1 domain and profilin in formin-mediated actin-filament elongation and nucleation.

Paul AS, Pollard TD.

Curr Biol. 2008 Jan 8;18(1):9-19. Epub 2007 Dec 20. Erratum in: Curr Biol. 2008 Feb 12;18(3):233. Paul, Aditya [corrected to Paul, Aditya S]; Pollard, Thomas [corrected to Pollard, Thomas D].

11.

The core FH2 domain of diaphanous-related formins is an elongated actin binding protein that inhibits polymerization.

Shimada A, Nyitrai M, Vetter IR, Kühlmann D, Bugyi B, Narumiya S, Geeves MA, Wittinghofer A.

Mol Cell. 2004 Feb 27;13(4):511-22.

12.

Review of the mechanism of processive actin filament elongation by formins.

Paul AS, Pollard TD.

Cell Motil Cytoskeleton. 2009 Aug;66(8):606-17. doi: 10.1002/cm.20379. Review.

13.

Mutations to the formin homology 2 domain of INF2 protein have unexpected effects on actin polymerization and severing.

Ramabhadran V, Gurel PS, Higgs HN.

J Biol Chem. 2012 Oct 5;287(41):34234-45. doi: 10.1074/jbc.M112.365122. Epub 2012 Aug 9.

14.

Dia-interacting protein modulates formin-mediated actin assembly at the cell cortex.

Eisenmann KM, Harris ES, Kitchen SM, Holman HA, Higgs HN, Alberts AS.

Curr Biol. 2007 Apr 3;17(7):579-91.

15.

Role of the C-terminal Extension of Formin 2 in Its Activation by Spire Protein and Processive Assembly of Actin Filaments.

Montaville P, Kühn S, Compper C, Carlier MF.

J Biol Chem. 2016 Feb 12;291(7):3302-18. doi: 10.1074/jbc.M115.681379. Epub 2015 Dec 14.

16.

The role of formin tails in actin nucleation, processive elongation, and filament bundling.

Vizcarra CL, Bor B, Quinlan ME.

J Biol Chem. 2014 Oct 31;289(44):30602-13. doi: 10.1074/jbc.M114.588368. Epub 2014 Sep 22.

17.

Crystal structure of the Formin mDia1 in autoinhibited conformation.

Otomo T, Tomchick DR, Otomo C, Machius M, Rosen MK.

PLoS One. 2010 Sep 30;5(9). pii: e12896. doi: 10.1371/journal.pone.0012896.

19.

Crystal structures of a Formin Homology-2 domain reveal a tethered dimer architecture.

Xu Y, Moseley JB, Sagot I, Poy F, Pellman D, Goode BL, Eck MJ.

Cell. 2004 Mar 5;116(5):711-23.

20.

How ATP hydrolysis controls filament assembly from profilin-actin: implication for formin processivity.

Romero S, Didry D, Larquet E, Boisset N, Pantaloni D, Carlier MF.

J Biol Chem. 2007 Mar 16;282(11):8435-45. Epub 2007 Jan 7.

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