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Items: 1 to 20 of 207

1.

Identification and structural characterization of a broadly neutralizing antibody targeting a novel conserved epitope on the influenza virus H5N1 hemagglutinin.

Du L, Jin L, Zhao G, Sun S, Li J, Yu H, Li Y, Zheng BJ, Liddington RC, Zhou Y, Jiang S.

J Virol. 2013 Feb;87(4):2215-25. doi: 10.1128/JVI.02344-12. Epub 2012 Dec 5.

2.

An antibody against a novel and conserved epitope in the hemagglutinin 1 subunit neutralizes numerous H5N1 influenza viruses.

Oh HL, Akerström S, Shen S, Bereczky S, Karlberg H, Klingström J, Lal SK, Mirazimi A, Tan YJ.

J Virol. 2010 Aug;84(16):8275-86. doi: 10.1128/JVI.02593-09. Epub 2010 Jun 2.

3.

A novel humanized antibody neutralizes H5N1 influenza virus via two different mechanisms.

Tan Y, Ng Q, Jia Q, Kwang J, He F.

J Virol. 2015 Apr;89(7):3712-22. doi: 10.1128/JVI.03014-14. Epub 2015 Jan 21.

4.

A human antibody recognizing a conserved epitope of H5 hemagglutinin broadly neutralizes highly pathogenic avian influenza H5N1 viruses.

Hu H, Voss J, Zhang G, Buchy P, Zuo T, Wang L, Wang F, Zhou F, Wang G, Tsai C, Calder L, Gamblin SJ, Zhang L, Deubel V, Zhou B, Skehel JJ, Zhou P.

J Virol. 2012 Mar;86(6):2978-89. doi: 10.1128/JVI.06665-11. Epub 2012 Jan 11.

5.

A unique and conserved neutralization epitope in H5N1 influenza viruses identified by an antibody against the A/Goose/Guangdong/1/96 hemagglutinin.

Zhu X, Guo YH, Jiang T, Wang YD, Chan KH, Li XF, Yu W, McBride R, Paulson JC, Yuen KY, Qin CF, Che XY, Wilson IA.

J Virol. 2013 Dec;87(23):12619-35. doi: 10.1128/JVI.01577-13. Epub 2013 Sep 18.

6.

A novel neutralizing antibody against diverse clades of H5N1 influenza virus and its mutants capable of airborne transmission.

Wu R, Li X, Leung HC, Cao Z, Qiu Z, Zhou Y, Zheng BJ, He Y.

Antiviral Res. 2014 Jun;106:13-23. doi: 10.1016/j.antiviral.2014.03.005. Epub 2014 Mar 25.

PMID:
24681124
7.

Unmasking Stem-Specific Neutralizing Epitopes by Abolishing N-Linked Glycosylation Sites of Influenza Virus Hemagglutinin Proteins for Vaccine Design.

Liu WC, Jan JT, Huang YJ, Chen TH, Wu SC.

J Virol. 2016 Sep 12;90(19):8496-508. doi: 10.1128/JVI.00880-16. Print 2016 Oct 1.

8.

DNA prime and virus-like particle boost from a single H5N1 strain elicits broadly neutralizing antibody responses against head region of H5 hemagglutinin.

Wang G, Zhou F, Buchy P, Zuo T, Hu H, Liu J, Song Y, Ding H, Tsai C, Chen Z, Zhang L, Deubel V, Zhou P.

J Infect Dis. 2014 Mar 1;209(5):676-85. doi: 10.1093/infdis/jit414. Epub 2013 Aug 2.

PMID:
23911711
9.

Monovalent H5 vaccine based on epitope-chimeric HA provides broad cross-clade protection against variant H5N1 viruses in mice.

He F, Prabakaran M, Rajesh Kumar S, Tan Y, Kwang J.

Antiviral Res. 2014 May;105:143-51. doi: 10.1016/j.antiviral.2014.03.002. Epub 2014 Mar 15.

PMID:
24637255
10.

A broadly neutralizing human monoclonal antibody directed against a novel conserved epitope on the influenza virus H3 hemagglutinin globular head.

Benjamin E, Wang W, McAuliffe JM, Palmer-Hill FJ, Kallewaard NL, Chen Z, Suzich JA, Blair WS, Jin H, Zhu Q.

J Virol. 2014 Jun;88(12):6743-50. doi: 10.1128/JVI.03562-13. Epub 2014 Apr 2.

11.

Divergent Requirement of Fc-Fcγ Receptor Interactions for In Vivo Protection against Influenza Viruses by Two Pan-H5 Hemagglutinin Antibodies.

Wang S, Ren H, Jiang W, Chen H, Hu H, Chen Z, Zhou P.

J Virol. 2017 May 12;91(11). pii: e02065-16. doi: 10.1128/JVI.02065-16. Print 2017 Jun 1.

12.

Reverse engineering the antigenic architecture of the haemagglutinin from influenza H5N1 clade 1 and 2.2 viruses with fine epitope mapping using monoclonal antibodies.

Rockman S, Camuglia S, Vandenberg K, Ong C, Baker MA, Nation RL, Li J, Velkov T.

Mol Immunol. 2013 Apr;53(4):435-42. doi: 10.1016/j.molimm.2012.10.001. Epub 2012 Nov 3.

PMID:
23127859
13.

Human Monoclonal Antibody 81.39a Effectively Neutralizes Emerging Influenza A Viruses of Group 1 and 2 Hemagglutinins.

Marjuki H, Mishin VP, Chai N, Tan MW, Newton EM, Tegeris J, Erlandson K, Willis M, Jones J, Davis T, Stevens J, Gubareva LV.

J Virol. 2016 Nov 14;90(23):10446-10458. Print 2016 Dec 1.

14.

The epitope and neutralization mechanism of AVFluIgG01, a broad-reactive human monoclonal antibody against H5N1 influenza virus.

Cao Z, Meng J, Li X, Wu R, Huang Y, He Y.

PLoS One. 2012;7(5):e38126. doi: 10.1371/journal.pone.0038126. Epub 2012 May 25.

15.

A non-VH1-69 heterosubtypic neutralizing human monoclonal antibody protects mice against H1N1 and H5N1 viruses.

De Marco D, Clementi N, Mancini N, Solforosi L, Moreno GJ, Sun X, Tumpey TM, Gubareva LV, Mishin V, Clementi M, Burioni R.

PLoS One. 2012;7(4):e34415. doi: 10.1371/journal.pone.0034415. Epub 2012 Apr 4.

16.

A critical HA1 neutralizing domain of H5N1 influenza in an optimal conformation induces strong cross-protection.

Du L, Zhao G, Sun S, Zhang X, Zhou X, Guo Y, Li Y, Zhou Y, Jiang S.

PLoS One. 2013;8(1):e53568. doi: 10.1371/journal.pone.0053568. Epub 2013 Jan 8.

17.

Characterization of a broadly neutralizing monoclonal antibody that targets the fusion domain of group 2 influenza A virus hemagglutinin.

Tan GS, Lee PS, Hoffman RM, Mazel-Sanchez B, Krammer F, Leon PE, Ward AB, Wilson IA, Palese P.

J Virol. 2014 Dec;88(23):13580-92. doi: 10.1128/JVI.02289-14. Epub 2014 Sep 10.

18.

Structures of complexes formed by H5 influenza hemagglutinin with a potent broadly neutralizing human monoclonal antibody.

Xiong X, Corti D, Liu J, Pinna D, Foglierini M, Calder LJ, Martin SR, Lin YP, Walker PA, Collins PJ, Monne I, Suguitan AL Jr, Santos C, Temperton NJ, Subbarao K, Lanzavecchia A, Gamblin SJ, Skehel JJ.

Proc Natl Acad Sci U S A. 2015 Jul 28;112(30):9430-5. doi: 10.1073/pnas.1510816112. Epub 2015 Jul 13.

19.

Characterization of cross-clade monoclonal antibodies against H5N1 highly pathogenic avian influenza virus and their application to the antigenic analysis of diverse H5 subtype viruses.

Gronsang D, Bui AN, Trinh DQ, Bui VN, Nguyen KV, Can MX, Omatsu T, Mizutani T, Nagai M, Katayama Y, Thampaisarn R, Ogawa H, Imai K.

Arch Virol. 2017 Aug;162(8):2257-2269. doi: 10.1007/s00705-017-3350-0. Epub 2017 Apr 12.

PMID:
28405766
20.

Induction of broadly reactive anti-hemagglutinin stalk antibodies by an H5N1 vaccine in humans.

Nachbagauer R, Wohlbold TJ, Hirsh A, Hai R, Sjursen H, Palese P, Cox RJ, Krammer F.

J Virol. 2014 Nov;88(22):13260-8. doi: 10.1128/JVI.02133-14. Epub 2014 Sep 10.

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