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Items: 1 to 20 of 239

1.

CDR-H3 diversity is not required for antigen recognition by synthetic antibodies.

Persson H, Ye W, Wernimont A, Adams JJ, Koide A, Koide S, Lam R, Sidhu SS.

J Mol Biol. 2013 Feb 22;425(4):803-11. doi: 10.1016/j.jmb.2012.11.037. Epub 2012 Dec 3.

2.

High-affinity human antibodies from phage-displayed synthetic Fab libraries with a single framework scaffold.

Lee CV, Liang WC, Dennis MS, Eigenbrot C, Sidhu SS, Fuh G.

J Mol Biol. 2004 Jul 23;340(5):1073-93.

PMID:
15236968
3.

Phage-displayed antibody libraries of synthetic heavy chain complementarity determining regions.

Sidhu SS, Li B, Chen Y, Fellouse FA, Eigenbrot C, Fuh G.

J Mol Biol. 2004 Apr 23;338(2):299-310.

PMID:
15066433
4.

A novel heavy domain antibody library with functionally optimized complementarity determining regions.

Mandrup OA, Friis NA, Lykkemark S, Just J, Kristensen P.

PLoS One. 2013 Oct 8;8(10):e76834. doi: 10.1371/journal.pone.0076834. eCollection 2013.

5.

The human combinatorial antibody library HuCAL GOLD combines diversification of all six CDRs according to the natural immune system with a novel display method for efficient selection of high-affinity antibodies.

Rothe C, Urlinger S, Löhning C, Prassler J, Stark Y, Jäger U, Hubner B, Bardroff M, Pradel I, Boss M, Bittlingmaier R, Bataa T, Frisch C, Brocks B, Honegger A, Urban M.

J Mol Biol. 2008 Feb 29;376(4):1182-200. doi: 10.1016/j.jmb.2007.12.018. Epub 2007 Dec 15.

PMID:
18191144
6.

Expressed murine and human CDR-H3 intervals of equal length exhibit distinct repertoires that differ in their amino acid composition and predicted range of structures.

Zemlin M, Klinger M, Link J, Zemlin C, Bauer K, Engler JA, Schroeder HW Jr, Kirkham PM.

J Mol Biol. 2003 Dec 5;334(4):733-49.

PMID:
14636599
7.

High-throughput generation of synthetic antibodies from highly functional minimalist phage-displayed libraries.

Fellouse FA, Esaki K, Birtalan S, Raptis D, Cancasci VJ, Koide A, Jhurani P, Vasser M, Wiesmann C, Kossiakoff AA, Koide S, Sidhu SS.

J Mol Biol. 2007 Nov 2;373(4):924-40. Epub 2007 Aug 19.

PMID:
17825836
8.

Synthetic antibodies from a four-amino-acid code: a dominant role for tyrosine in antigen recognition.

Fellouse FA, Wiesmann C, Sidhu SS.

Proc Natl Acad Sci U S A. 2004 Aug 24;101(34):12467-72. Epub 2004 Aug 11.

9.

Systematic classification of CDR-L3 in antibodies: implications of the light chain subtypes and the VL-VH interface.

Kuroda D, Shirai H, Kobori M, Nakamura H.

Proteins. 2009 Apr;75(1):139-46. doi: 10.1002/prot.22230.

PMID:
18798566
10.

Design and construction of synthetic phage-displayed Fab libraries.

Bostrom J, Fuh G.

Methods Mol Biol. 2009;562:17-35. doi: 10.1007/978-1-60327-302-2_2.

PMID:
19554284
11.

Molecular features of the broadly neutralizing immunoglobulin G1 b12 required for recognition of human immunodeficiency virus type 1 gp120.

Zwick MB, Parren PW, Saphire EO, Church S, Wang M, Scott JK, Dawson PE, Wilson IA, Burton DR.

J Virol. 2003 May;77(10):5863-76.

12.

Predicting antibody complementarity determining region structures without classification.

Choi Y, Deane CM.

Mol Biosyst. 2011 Dec;7(12):3327-34. doi: 10.1039/c1mb05223c. Epub 2011 Oct 20.

PMID:
22011953
13.

The functional repertoire of rabbit antibodies and antibody discovery via next-generation sequencing.

Kodangattil S, Huard C, Ross C, Li J, Gao H, Mascioni A, Hodawadekar S, Naik S, Min-debartolo J, Visintin A, Almagro JC.

MAbs. 2014 May-Jun;6(3):628-36. doi: 10.4161/mabs.28059. Epub 2014 Jan 30.

14.

Comprehensive interrogation of a minimalist synthetic CDR-H3 library and its ability to generate antibodies with therapeutic potential.

Mahon CM, Lambert MA, Glanville J, Wade JM, Fennell BJ, Krebs MR, Armellino D, Yang S, Liu X, O'Sullivan CM, Autin B, Oficjalska K, Bloom L, Paulsen J, Gill D, Damelin M, Cunningham O, Finlay WJ.

J Mol Biol. 2013 May 27;425(10):1712-30. doi: 10.1016/j.jmb.2013.02.015. Epub 2013 Feb 19.

PMID:
23429058
15.

Enhanced conformational diversity search of CDR-H3 in antibodies: role of the first CDR-H3 residue.

Kim ST, Shirai H, Nakajima N, Higo J, Nakamura H.

Proteins. 1999 Dec 1;37(4):683-96.

PMID:
10651282
17.

A universal combinatorial design of antibody framework to graft distinct CDR sequences: a bioinformatics approach.

Haidar JN, Yuan QA, Zeng L, Snavely M, Luna X, Zhang H, Zhu W, Ludwig DL, Zhu Z.

Proteins. 2012 Mar;80(3):896-912. doi: 10.1002/prot.23246. Epub 2011 Dec 16. Erratum in: Proteins. 2013 Sep;81(9):1677.

PMID:
22180101
18.

Length of the antibody heavy chain complementarity determining region 3 as a specificity-determining factor.

Barrios Y, Jirholt P, Ohlin M.

J Mol Recognit. 2004 Jul-Aug;17(4):332-8.

PMID:
15227640
19.

Structural classification of CDR-H3 revisited: a lesson in antibody modeling.

Kuroda D, Shirai H, Kobori M, Nakamura H.

Proteins. 2008 Nov 15;73(3):608-20. doi: 10.1002/prot.22087.

PMID:
18473362
20.

A large human domain antibody library combining heavy and light chain CDR3 diversity.

Chen W, Zhu Z, Feng Y, Dimitrov DS.

Mol Immunol. 2010 Jan;47(4):912-21. doi: 10.1016/j.molimm.2009.09.039. Epub 2009 Nov 1.

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