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Items: 1 to 20 of 84


The superhealing MRL background improves muscular dystrophy.

Heydemann A, Swaggart KA, Kim GH, Holley-Cuthrell J, Hadhazy M, McNally EM.

Skelet Muscle. 2012 Dec 5;2(1):26. doi: 10.1186/2044-5040-2-26.


Cardiac function in muscular dystrophy associates with abdominal muscle pathology.

Gardner BB, Swaggart KA, Kim G, Watson S, McNally EM.

J Neuromuscul Dis. 2015;2(1):39-49.


Distinct genetic regions modify specific muscle groups in muscular dystrophy.

Swaggart KA, Heydemann A, Palmer AA, McNally EM.

Physiol Genomics. 2011 Jan 7;43(1):24-31. doi: 10.1152/physiolgenomics.00172.2010. Epub 2010 Oct 19.


Modifiers of heart and muscle function: where genetics meets physiology.

Swaggart KA, McNally EM.

Exp Physiol. 2014 Apr;99(4):621-6. doi: 10.1113/expphysiol.2013.075887. Epub 2013 Nov 8. Review.


Biochemical and Functional Comparisons of mdx and Sgcg(-/-) Muscular Dystrophy Mouse Models.

Roberts NW, Holley-Cuthrell J, Gonzalez-Vega M, Mull AJ, Heydemann A.

Biomed Res Int. 2015;2015:131436. doi: 10.1155/2015/131436. Epub 2015 May 3.


Genetic disruption of calcineurin improves skeletal muscle pathology and cardiac disease in a mouse model of limb-girdle muscular dystrophy.

Parsons SA, Millay DP, Sargent MA, Naya FJ, McNally EM, Sweeney HL, Molkentin JD.

J Biol Chem. 2007 Mar 30;282(13):10068-78. Epub 2007 Feb 7.


Autonomic, locomotor and cardiac abnormalities in a mouse model of muscular dystrophy: targeting the renin-angiotensin system.

Sabharwal R, Chapleau MW.

Exp Physiol. 2014 Apr;99(4):627-31. doi: 10.1113/expphysiol.2013.074336. Epub 2013 Dec 13. Review.


Extraocular muscle is spared despite the absence of an intact sarcoglycan complex in gamma- or delta-sarcoglycan-deficient mice.

Porter JD, Merriam AP, Hack AA, Andrade FH, McNally EM.

Neuromuscul Disord. 2001 Mar;11(2):197-207.


Fibrosis and inflammation are greater in muscles of beta-sarcoglycan-null mouse than mdx mouse.

Gibertini S, Zanotti S, Savadori P, Curcio M, Saredi S, Salerno F, Andreetta F, Bernasconi P, Mantegazza R, Mora M.

Cell Tissue Res. 2014 May;356(2):427-43. doi: 10.1007/s00441-014-1854-4. Epub 2014 Apr 11.


Mutations in the delta-sarcoglycan gene are a rare cause of autosomal recessive limb-girdle muscular dystrophy (LGMD2).

Duggan DJ, Manchester D, Stears KP, Mathews DJ, Hart C, Hoffman EP.

Neurogenetics. 1997 May;1(1):49-58.


Distinct pathophysiological mechanisms of cardiomyopathy in hearts lacking dystrophin or the sarcoglycan complex.

Townsend D, Yasuda S, McNally E, Metzger JM.

FASEB J. 2011 Sep;25(9):3106-14. doi: 10.1096/fj.10-178913. Epub 2011 Jun 10.


Genetic background influences muscular dystrophy.

Heydemann A, Huber JM, Demonbreun A, Hadhazy M, McNally EM.

Neuromuscul Disord. 2005 Oct;15(9-10):601-9.


Disruption of the beta-sarcoglycan gene reveals pathogenetic complexity of limb-girdle muscular dystrophy type 2E.

Durbeej M, Cohn RD, Hrstka RF, Moore SA, Allamand V, Davidson BL, Williamson RA, Campbell KP.

Mol Cell. 2000 Jan;5(1):141-51.


Animal models for muscular dystrophy show different patterns of sarcolemmal disruption.

Straub V, Rafael JA, Chamberlain JS, Campbell KP.

J Cell Biol. 1997 Oct 20;139(2):375-85.


Membrane sealant Poloxamer P188 protects against isoproterenol induced cardiomyopathy in dystrophin deficient mice.

Spurney CF, Guerron AD, Yu Q, Sali A, van der Meulen JH, Hoffman EP, Nagaraju K.

BMC Cardiovasc Disord. 2011 May 16;11:20. doi: 10.1186/1471-2261-11-20.


Leaky ryanodine receptors in β-sarcoglycan deficient mice: a potential common defect in muscular dystrophy.

Andersson DC, Meli AC, Reiken S, Betzenhauser MJ, Umanskaya A, Shiomi T, D'Armiento J, Marks AR.

Skelet Muscle. 2012 May 28;2(1):9. doi: 10.1186/2044-5040-2-9.


Muscle degeneration without mechanical injury in sarcoglycan deficiency.

Hack AA, Cordier L, Shoturma DI, Lam MY, Sweeney HL, McNally EM.

Proc Natl Acad Sci U S A. 1999 Sep 14;96(19):10723-8.


Increased fibrosis and progression to heart failure in MRL mice following ischemia/reperfusion injury.

Smiley D, Smith MA, Carreira V, Jiang M, Koch SE, Kelley M, Rubinstein J, Jones WK, Tranter M.

Cardiovasc Pathol. 2014 Nov-Dec;23(6):327-34. doi: 10.1016/j.carpath.2014.06.001. Epub 2014 Jun 13.


Differential requirement for individual sarcoglycans and dystrophin in the assembly and function of the dystrophin-glycoprotein complex.

Hack AA, Lam MY, Cordier L, Shoturma DI, Ly CT, Hadhazy MA, Hadhazy MR, Sweeney HL, McNally EM.

J Cell Sci. 2000 Jul;113 ( Pt 14):2535-44.


Severe murine limb-girdle muscular dystrophy type 2C pathology is diminished by FTY720 treatment.

Heydemann A.

Muscle Nerve. 2016 Dec 9. doi: 10.1002/mus.25503. [Epub ahead of print]


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