Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 118

1.

Endogenous protein C has a protective role during Gram-negative pneumosepsis (melioidosis).

Kager LM, Wiersinga WJ, Roelofs JJ, Meijers JC, Zeerleder SS, Esmon CT, van't Veer C, van der Poll T.

J Thromb Haemost. 2013 Feb;11(2):282-92. doi: 10.1111/jth.12094.

2.

Overexpression of activated protein C is detrimental during severe experimental gram-negative sepsis (melioidosis).

Kager LM, Wiersinga WJ, Roelofs JJ, de Boer OJ, Meijers JC, Isermann B, van't Veer C, Van der Poll T.

Crit Care Med. 2013 Oct;41(10):e266-74. doi: 10.1097/CCM.0b013e31828a4316.

PMID:
23887233
3.

A thrombomodulin mutation that impairs active protein C generation is detrimental in severe pneumonia-derived gram-negative sepsis (melioidosis).

Kager LM, Wiersinga WJ, Roelofs JJ, de Boer OJ, Weiler H, van 't Veer C, van der Poll T.

PLoS Negl Trop Dis. 2014 Apr 24;8(4):e2819. doi: 10.1371/journal.pntd.0002819. eCollection 2014 Apr.

4.

Endogenous α2-antiplasmin is protective during severe gram-negative sepsis (melioidosis).

Kager LM, Weehuizen TA, Wiersinga WJ, Roelofs JJ, Meijers JC, Dondorp AM, van 't Veer C, van der Poll T.

Am J Respir Crit Care Med. 2013 Oct 15;188(8):967-75. doi: 10.1164/rccm.201307-1344OC.

PMID:
23992406
5.

Endogenous activated protein C signaling is critical to protection of mice from lipopolysaccaride-induced septic shock.

Xu J, Ji Y, Zhang X, Drake M, Esmon CT.

J Thromb Haemost. 2009 May;7(5):851-6. doi: 10.1111/j.1538-7836.2009.03333.x. Epub 2009 Mar 5.

6.

Deficiency of protease-activated receptor-1 limits bacterial dissemination during severe Gram-negative sepsis (melioidosis).

Kager LM, Wiersinga WJ, Roelofs JJ, van 't Veer C, van der Poll T.

Microbes Infect. 2014 Feb;16(2):171-4. doi: 10.1016/j.micinf.2013.11.001. Epub 2013 Nov 13.

PMID:
24239704
7.

Plasminogen activator inhibitor type I contributes to protective immunity during experimental Gram-negative sepsis (melioidosis).

Kager LM, Wiersinga WJ, Roelofs JJ, Meijers JC, Levi M, Van't Veer C, van der Poll T.

J Thromb Haemost. 2011 Oct;9(10):2020-8. doi: 10.1111/j.1538-7836.2011.04473.x.

8.

Endogenous tissue-type plasminogen activator impairs host defense during severe experimental Gram-negative sepsis (melioidosis)*.

Kager LM, Wiersinga WJ, Roelofs JJ, Meijers JC, Levi M, Van't Veer C, van der Poll T.

Crit Care Med. 2012 Jul;40(7):2168-75. doi: 10.1097/CCM.0b013e31824ea05e.

PMID:
22564963
9.

The coagulation system in melioidosis: from pathogenesis to new treatment strategies.

Kager LM, van der Poll T, Wiersinga WJ.

Expert Rev Anti Infect Ther. 2014 Aug;12(8):993-1002. doi: 10.1586/14787210.2014.928198. Epub 2014 Jun 25. Review.

PMID:
24962103
10.

Crosstalk between inflammation and coagulation: the lessons of sepsis.

van der Poll T, Levi M.

Curr Vasc Pharmacol. 2012 Sep;10(5):632-8. Review.

PMID:
22272914
11.

Mice lacking the lectin-like domain of thrombomodulin are protected against melioidosis.

Kager LM, Wiersinga WJ, Roelofs JJ, Stroo I, Achouiti A, van 't Veer C, Conway EM, van der Poll T.

Crit Care Med. 2014 Mar;42(3):e221-30. doi: 10.1097/CCM.0000000000000134.

PMID:
24399241
12.

Urokinase receptor is necessary for bacterial defense against pneumonia-derived septic melioidosis by facilitating phagocytosis.

Wiersinga WJ, Kager LM, Hovius JW, van der Windt GJ, de Vos AF, Meijers JC, Roelofs JJ, Dondorp A, Levi M, Day NP, Peacock SJ, van der Poll T.

J Immunol. 2010 Mar 15;184(6):3079-86. doi: 10.4049/jimmunol.0901008. Epub 2010 Feb 8.

13.

The endothelial protein C receptor and activated protein C play a limited role in host defense during experimental tuberculosis.

Kager LM, Roelofs JJ, de Vos AF, Wieland CW, Schouten M, Meijers JC, Isermann B, Van't Veer C, Esmon CT, van der Poll T.

Thromb Haemost. 2013 Apr;109(4):726-37. doi: 10.1160/TH12-11-0859. Epub 2013 Jan 24.

PMID:
23348224
14.

The cytoprotective protein C pathway.

Mosnier LO, Zlokovic BV, Griffin JH.

Blood. 2007 Apr 15;109(8):3161-72. Epub 2006 Nov 16. Review.

15.

CD14 impairs host defense against gram-negative sepsis caused by Burkholderia pseudomallei in mice.

Wiersinga WJ, de Vos AF, Wieland CW, Leendertse M, Roelofs JJ, van der Poll T.

J Infect Dis. 2008 Nov 1;198(9):1388-97. doi: 10.1086/592220.

PMID:
18855560
16.

Overexpression of the endothelial protein C receptor is detrimental during pneumonia-derived gram-negative sepsis (Melioidosis).

Kager LM, Schouten M, Wiersinga WJ, de Boer JD, Lattenist LC, Roelofs JJ, Meijers JC, Levi M, Dondorp AM, Esmon CT, van 't Veer C, van der Poll T.

PLoS Negl Trop Dis. 2013 Jul 11;7(7):e2306. doi: 10.1371/journal.pntd.0002306. Print 2013.

17.

The cytoprotective effects of endogenous activated protein C reduce activation of coagulation during murine pneumococcal pneumonia and sepsis.

Schouten M, van 't Veer C, Poulussen N, Meijers JC, Levi M, Esmon CT, van der Poll T.

Thromb Res. 2015 Mar;135(3):537-43. doi: 10.1016/j.thromres.2014.12.020. Epub 2015 Jan 2.

PMID:
25586194
18.

Diabetes does not influence activation of coagulation, fibrinolysis or anticoagulant pathways in Gram-negative sepsis (melioidosis).

Koh GC, Meijers JC, Maude RR, Limmathurotsakul D, Day NP, Peacock SJ, van der Poll T, Wiersinga WJ.

Thromb Haemost. 2011 Dec;106(6):1139-48. doi: 10.1160/TH11-07-0504. Epub 2011 Oct 6.

PMID:
21979378
19.

Identification of a specific exosite on activated protein C for interaction with protease-activated receptor 1.

Yang L, Bae JS, Manithody C, Rezaie AR.

J Biol Chem. 2007 Aug 31;282(35):25493-500. Epub 2007 Jun 19.

20.

Endogenous activated protein C limits cancer cell extravasation through sphingosine-1-phosphate receptor 1-mediated vascular endothelial barrier enhancement.

Van Sluis GL, Niers TM, Esmon CT, Tigchelaar W, Richel DJ, Buller HR, Van Noorden CJ, Spek CA.

Blood. 2009 Aug 27;114(9):1968-73. doi: 10.1182/blood-2009-04-217679. Epub 2009 Jul 1.

Supplemental Content

Support Center