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Items: 1 to 20 of 138

1.

Electrical field stimulation induces cardiac fibroblast proliferation through the calcineurin-NFAT pathway.

Chen QQ, Zhang W, Chen XF, Bao YJ, Wang J, Zhu WZ.

Can J Physiol Pharmacol. 2012 Dec;90(12):1611-22. doi: 10.1139/y2012-133. Epub 2012 Nov 26.

PMID:
23210440
2.

Phenylephrine promotes cardiac fibroblast proliferation through calcineurin-NFAT pathway.

Wang J, Wang Y, Zhang W, Zhao X, Chen X, Xiao W, Zhang L, Chen Y, Zhu W.

Front Biosci (Landmark Ed). 2016 Jan 1;21:502-13.

PMID:
26709790
3.

CaMKII negatively regulates calcineurin-NFAT signaling in cardiac myocytes.

MacDonnell SM, Weisser-Thomas J, Kubo H, Hanscome M, Liu Q, Jaleel N, Berretta R, Chen X, Brown JH, Sabri AK, Molkentin JD, Houser SR.

Circ Res. 2009 Aug 14;105(4):316-25. doi: 10.1161/CIRCRESAHA.109.194035. Epub 2009 Jul 16.

4.

Polydatin attenuates cardiac hypertrophy through modulation of cardiac Ca2+ handling and calcineurin-NFAT signaling pathway.

Ding W, Dong M, Deng J, Yan D, Liu Y, Xu T, Liu J.

Am J Physiol Heart Circ Physiol. 2014 Sep 1;307(5):H792-802. doi: 10.1152/ajpheart.00017.2014. Epub 2014 Jul 11.

5.

Ca(2+) influx through L-type Ca(2+) channels and transient receptor potential channels activates pathological hypertrophy signaling.

Gao H, Wang F, Wang W, Makarewich CA, Zhang H, Kubo H, Berretta RM, Barr LA, Molkentin JD, Houser SR.

J Mol Cell Cardiol. 2012 Nov;53(5):657-67. doi: 10.1016/j.yjmcc.2012.08.005. Epub 2012 Aug 21.

6.

Syndecan-4 signaling via NFAT regulates extracellular matrix production and cardiac myofibroblast differentiation in response to mechanical stress.

Herum KM, Lunde IG, Skrbic B, Florholmen G, Behmen D, Sjaastad I, Carlson CR, Gomez MF, Christensen G.

J Mol Cell Cardiol. 2013 Jan;54:73-81. doi: 10.1016/j.yjmcc.2012.11.006. Epub 2012 Nov 22.

PMID:
23178899
7.

Activation of peroxisome proliferator-activated receptor gamma inhibits endothelin-1-induced cardiac hypertrophy via the calcineurin/NFAT signaling pathway.

Bao Y, Li R, Jiang J, Cai B, Gao J, Le K, Zhang F, Chen S, Liu P.

Mol Cell Biochem. 2008 Oct;317(1-2):189-96. doi: 10.1007/s11010-008-9848-8. Epub 2008 Jul 4.

PMID:
18600431
8.

Leptin-induced cardiomyocyte hypertrophy reveals both calcium-dependent and calcium-independent/RhoA-dependent calcineurin activation and NFAT nuclear translocation.

Rajapurohitam V, Izaddoustdar F, Martinez-Abundis E, Karmazyn M.

Cell Signal. 2012 Dec;24(12):2283-90. doi: 10.1016/j.cellsig.2012.07.025. Epub 2012 Aug 15.

PMID:
22917533
9.

Direct interaction and reciprocal regulation between ASK1 and calcineurin-NFAT control cardiomyocyte death and growth.

Liu Q, Wilkins BJ, Lee YJ, Ichijo H, Molkentin JD.

Mol Cell Biol. 2006 May;26(10):3785-97.

10.

Low UVA doses activate the transcription factor NFAT in human fibroblasts by a calcium-calcineurin pathway.

Mazière C, Morlière P, Louandre C, Conte MA, Gomilla C, Santus R, Antonicelli F, Hornebeck W, Mazière JC.

Free Radic Biol Med. 2005 Dec 15;39(12):1629-37. Epub 2005 Sep 8.

PMID:
16298688
11.

Lipopolysaccharide induces cellular hypertrophy through calcineurin/NFAT-3 signaling pathway in H9c2 myocardiac cells.

Liu CJ, Cheng YC, Lee KW, Hsu HH, Chu CH, Tsai FJ, Tsai CH, Chu CY, Liu JY, Kuo WW, Huang CY.

Mol Cell Biochem. 2008 Jun;313(1-2):167-78. doi: 10.1007/s11010-008-9754-0. Epub 2008 Apr 9.

PMID:
18398669
12.

The essential role of MEKK3 signaling in angiotensin II-induced calcineurin/nuclear factor of activated T-cells activation.

Abbasi S, Su B, Kellems RE, Yang J, Xia Y.

J Biol Chem. 2005 Nov 4;280(44):36737-46. Epub 2005 Aug 26.

13.

Activation of Na+/H+ exchanger 1 is sufficient to generate Ca2+ signals that induce cardiac hypertrophy and heart failure.

Nakamura TY, Iwata Y, Arai Y, Komamura K, Wakabayashi S.

Circ Res. 2008 Oct 10;103(8):891-9. doi: 10.1161/CIRCRESAHA.108.175141. Epub 2008 Sep 5.

14.

Regulation of nerve growth factor in the heart: the role of the calcineurin-NFAT pathway.

Rana OR, Saygili E, Meyer C, Gemein C, Krüttgen A, Andrzejewski MG, Ludwig A, Schotten U, Schwinger RH, Weber C, Weis J, Mischke K, Rassaf T, Kelm M, Schauerte P.

J Mol Cell Cardiol. 2009 Apr;46(4):568-78. doi: 10.1016/j.yjmcc.2008.12.006. Epub 2008 Dec 25.

PMID:
19150448
15.

Na(+)/H(+) exchanger 1 directly binds to calcineurin A and activates downstream NFAT signaling, leading to cardiomyocyte hypertrophy.

Hisamitsu T, Nakamura TY, Wakabayashi S.

Mol Cell Biol. 2012 Aug;32(16):3265-80. doi: 10.1128/MCB.00145-12. Epub 2012 Jun 11.

16.

Inhibition of calcium-calmodulin-dependent kinase II suppresses cardiac fibroblast proliferation and extracellular matrix secretion.

Zhang W, Chen DQ, Qi F, Wang J, Xiao WY, Zhu WZ.

J Cardiovasc Pharmacol. 2010 Jan;55(1):96-105. doi: 10.1097/FJC.0b013e3181c9548b.

PMID:
19935079
17.

Enhanced expression of DYRK1A in cardiomyocytes inhibits acute NFAT activation but does not prevent hypertrophy in vivo.

Grebe C, Klingebiel TM, Grau SP, Toischer K, Didié M, Jacobshagen C, Dullin C, Hasenfuss G, Seidler T.

Cardiovasc Res. 2011 Jun 1;90(3):521-8. doi: 10.1093/cvr/cvr023. Epub 2011 Jan 27.

PMID:
21273244
18.

Cardiac anti-remodelling effect of aerobic training is associated with a reduction in the calcineurin/NFAT signalling pathway in heart failure mice.

Oliveira RS, Ferreira JC, Gomes ER, Paixão NA, Rolim NP, Medeiros A, Guatimosim S, Brum PC.

J Physiol. 2009 Aug 1;587(Pt 15):3899-910. doi: 10.1113/jphysiol.2009.173948. Epub 2009 Jun 8.

20.

Isoform- and tissue-specific regulation of the Ca(2+)-sensitive transcription factor NFAT in cardiac myocytes and heart failure.

Rinne A, Kapur N, Molkentin JD, Pogwizd SM, Bers DM, Banach K, Blatter LA.

Am J Physiol Heart Circ Physiol. 2010 Jun;298(6):H2001-9. doi: 10.1152/ajpheart.01072.2009. Epub 2010 Mar 19.

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