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Items: 1 to 20 of 88

1.

Hsp90 inhibitors are efficacious against Kaposi Sarcoma by enhancing the degradation of the essential viral gene LANA, of the viral co-receptor EphA2 as well as other client proteins.

Chen W, Sin SH, Wen KW, Damania B, Dittmer DP.

PLoS Pathog. 2012;8(11):e1003048. doi: 10.1371/journal.ppat.1003048. Epub 2012 Nov 29.

2.

Site-specific association with host and viral chromatin by Kaposi's sarcoma-associated herpesvirus LANA and its reversal during lytic reactivation.

Mercier A, Arias C, Madrid AS, Holdorf MM, Ganem D.

J Virol. 2014 Jun;88(12):6762-77. doi: 10.1128/JVI.00268-14. Epub 2014 Apr 2.

3.

Kaposi's sarcoma-associated herpesvirus-encoded LANA can induce chromosomal instability through targeted degradation of the mitotic checkpoint kinase Bub1.

Sun Z, Xiao B, Jha HC, Lu J, Banerjee S, Robertson ES.

J Virol. 2014 Jul;88(13):7367-78. doi: 10.1128/JVI.00554-14. Epub 2014 Apr 16.

4.

Nucleophosmin phosphorylation by v-cyclin-CDK6 controls KSHV latency.

Sarek G, Järviluoma A, Moore HM, Tojkander S, Vartia S, Biberfeld P, Laiho M, Ojala PM.

PLoS Pathog. 2010 Mar 19;6(3):e1000818. doi: 10.1371/journal.ppat.1000818.

5.

KSHV downregulation of galectin-3 in Kaposi's sarcoma.

Alcendor DJ, Knobel SM, Desai P, Zhu WQ, Vigil HE, Hayward GS.

Glycobiology. 2010 May;20(5):521-32. doi: 10.1093/glycob/cwp204. Epub 2009 Dec 29.

7.

Identification of Kaposi's sarcoma-associated herpesvirus LANA regions important for episome segregation, replication, and persistence.

Vázquez Ede L, Carey VJ, Kaye KM.

J Virol. 2013 Nov;87(22):12270-83. doi: 10.1128/JVI.01243-13. Epub 2013 Sep 4.

8.

A structural basis for BRD2/4-mediated host chromatin interaction and oligomer assembly of Kaposi sarcoma-associated herpesvirus and murine gammaherpesvirus LANA proteins.

Hellert J, Weidner-Glunde M, Krausze J, Richter U, Adler H, Fedorov R, Pietrek M, Rückert J, Ritter C, Schulz TF, Lührs T.

PLoS Pathog. 2013;9(10):e1003640. doi: 10.1371/journal.ppat.1003640. Epub 2013 Oct 17.

9.

Cancer angiogenesis induced by Kaposi sarcoma-associated herpesvirus is mediated by EZH2.

He M, Zhang W, Bakken T, Schutten M, Toth Z, Jung JU, Gill P, Cannon M, Gao SJ.

Cancer Res. 2012 Jul 15;72(14):3582-92. doi: 10.1158/0008-5472.CAN-11-2876. Epub 2012 May 16. Erratum in: Cancer Res. 2013 Sep 1;73(17):5603-5.

10.
11.

Viral latent proteins as targets for Kaposi's sarcoma and Kaposi's sarcoma-associated herpesvirus (KSHV/HHV-8) induced lymphoma.

Staudt MR, Dittmer DP.

Curr Drug Targets Infect Disord. 2003 Jun;3(2):129-35. Review.

PMID:
12769790
12.

Physical and functional interactions between STAT3 and Kaposi's sarcoma-associated herpesvirus-encoded LANA.

Muromoto R, Okabe K, Fujimuro M, Sugiyama K, Yokosawa H, Seya T, Matsuda T.

FEBS Lett. 2006 Jan 9;580(1):93-8. Epub 2005 Dec 6.

14.

Kaposi's sarcoma-associated herpesvirus-encoded LANA associates with glucocorticoid receptor and enhances its transcriptional activities.

Togi S, Nakasuji M, Muromoto R, Ikeda O, Okabe K, Kitai Y, Kon S, Oritani K, Matsuda T.

Biochem Biophys Res Commun. 2015 Jul 31;463(3):395-400. doi: 10.1016/j.bbrc.2015.05.080. Epub 2015 May 29.

PMID:
26032496
15.

H2AX phosphorylation is important for LANA-mediated Kaposi's sarcoma-associated herpesvirus episome persistence.

Jha HC, Upadhyay SK, A J Prasad M, Lu J, Cai Q, Saha A, Robertson ES.

J Virol. 2013 May;87(9):5255-69. doi: 10.1128/JVI.03575-12. Epub 2013 Feb 28.

16.

A unique SUMO-2-interacting motif within LANA is essential for KSHV latency.

Cai Q, Cai S, Zhu C, Verma SC, Choi JY, Robertson ES.

PLoS Pathog. 2013;9(11):e1003750. doi: 10.1371/journal.ppat.1003750. Epub 2013 Nov 21.

17.

Bub1 in Complex with LANA Recruits PCNA To Regulate Kaposi's Sarcoma-Associated Herpesvirus Latent Replication and DNA Translesion Synthesis.

Sun Z, Jha HC, Robertson ES.

J Virol. 2015 Oct;89(20):10206-18. doi: 10.1128/JVI.01524-15. Epub 2015 Jul 29.

19.

Human herpesvirus 8/Kaposi sarcoma herpesvirus cell association during evolution of Kaposi sarcoma.

Pyakurel P, Massambu C, Castaños-Vélez E, Ericsson S, Kaaya E, Biberfeld P, Heiden T.

J Acquir Immune Defic Syndr. 2004 Jun 1;36(2):678-83.

PMID:
15167286

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