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Items: 1 to 20 of 143

1.

Forced interaction of cell surface proteins with Derlin-1 in the endoplasmic reticulum is sufficient to induce their dislocation into the cytosol for degradation.

Cho S, Lee M, Jun Y.

Biochem Biophys Res Commun. 2013 Jan 11;430(2):787-92. doi: 10.1016/j.bbrc.2012.11.068. Epub 2012 Dec 1.

PMID:
23206703
2.

The C-terminal amino acid of the MHC-I heavy chain is critical for binding to Derlin-1 in human cytomegalovirus US11-induced MHC-I degradation.

Cho S, Kim BY, Ahn K, Jun Y.

PLoS One. 2013 Aug 12;8(8):e72356. doi: 10.1371/journal.pone.0072356. eCollection 2013.

3.

TMEM129 is a Derlin-1 associated ERAD E3 ligase essential for virus-induced degradation of MHC-I.

van den Boomen DJ, Timms RT, Grice GL, Stagg HR, Skødt K, Dougan G, Nathan JA, Lehner PJ.

Proc Natl Acad Sci U S A. 2014 Aug 5;111(31):11425-30. doi: 10.1073/pnas.1409099111. Epub 2014 Jul 16.

4.

A membrane protein required for dislocation of misfolded proteins from the ER.

Lilley BN, Ploegh HL.

Nature. 2004 Jun 24;429(6994):834-40.

5.

Functional dissection of HCMV US11 in mediating the degradation of MHC class I molecules.

Lee SO, Hwang S, Park J, Park B, Jin BS, Lee S, Kim E, Cho S, Kim Y, Cho K, Shin J, Ahn K.

Biochem Biophys Res Commun. 2005 May 20;330(4):1262-7.

PMID:
15823579
6.
7.
8.

TRAM1 participates in human cytomegalovirus US2- and US11-mediated dislocation of an endoplasmic reticulum membrane glycoprotein.

Oresic K, Ng CL, Tortorella D.

J Biol Chem. 2009 Feb 27;284(9):5905-14. doi: 10.1074/jbc.M807568200. Epub 2009 Jan 2.

9.
10.

Signal peptide peptidase is required for dislocation from the endoplasmic reticulum.

Loureiro J, Lilley BN, Spooner E, Noriega V, Tortorella D, Ploegh HL.

Nature. 2006 Jun 15;441(7095):894-7. Epub 2006 May 31.

PMID:
16738546
11.

Ubiquitinylation of the cytosolic domain of a type I membrane protein is not required to initiate its dislocation from the endoplasmic reticulum.

Furman MH, Loureiro J, Ploegh HL, Tortorella D.

J Biol Chem. 2003 Sep 12;278(37):34804-11. Epub 2003 Jun 27.

12.
13.

Ubiquitin-dependent intramembrane rhomboid protease promotes ERAD of membrane proteins.

Fleig L, Bergbold N, Sahasrabudhe P, Geiger B, Kaltak L, Lemberg MK.

Mol Cell. 2012 Aug 24;47(4):558-69. doi: 10.1016/j.molcel.2012.06.008. Epub 2012 Jul 12.

14.

Identifying the ERAD ubiquitin E3 ligases for viral and cellular targeting of MHC class I.

van den Boomen DJ, Lehner PJ.

Mol Immunol. 2015 Dec;68(2 Pt A):106-11. doi: 10.1016/j.molimm.2015.07.005. Epub 2015 Jul 22. Review.

15.

Human cytomegalovirus-encoded US2 and US11 target unassembled MHC class I heavy chains for degradation.

Barel MT, Hassink GC, van Voorden S, Wiertz EJ.

Mol Immunol. 2006 Mar;43(8):1258-66. Epub 2005 Aug 10.

PMID:
16098592
16.

The TRC8 E3 ligase ubiquitinates MHC class I molecules before dislocation from the ER.

Stagg HR, Thomas M, van den Boomen D, Wiertz EJ, Drabkin HA, Gemmill RM, Lehner PJ.

J Cell Biol. 2009 Sep 7;186(5):685-92. doi: 10.1083/jcb.200906110. Epub 2009 Aug 31.

17.

A membrane protein complex mediates retro-translocation from the ER lumen into the cytosol.

Ye Y, Shibata Y, Yun C, Ron D, Rapoport TA.

Nature. 2004 Jun 24;429(6994):841-7.

18.

The HCMV gene products US2 and US11 target MHC class I molecules for degradation in the cytosol.

van der Wal FJ, Kikkert M, Wiertz E.

Curr Top Microbiol Immunol. 2002;269:37-55. Review.

PMID:
12224515
19.
20.

A novel mammalian ER-located J-protein, DNAJB14, can accelerate ERAD of misfolded membrane proteins.

Sopha P, Kadokura H, Yamamoto YH, Takeuchi M, Saito M, Tsuru A, Kohno K.

Cell Struct Funct. 2012;37(2):177-87. Epub 2012 Sep 27.

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