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Items: 1 to 20 of 71

1.

Upregulation of phase II enzymes through phytochemical activation of Nrf2 protects cardiomyocytes against oxidant stress.

Reuland DJ, Khademi S, Castle CJ, Irwin DC, McCord JM, Miller BF, Hamilton KL.

Free Radic Biol Med. 2013 Mar;56:102-11. doi: 10.1016/j.freeradbiomed.2012.11.016. Epub 2012 Nov 30.

PMID:
23201694
2.

Antioxidants and phase 2 enzymes in macrophages: regulation by Nrf2 signaling and protection against oxidative and electrophilic stress.

Zhu H, Jia Z, Zhang L, Yamamoto M, Misra HP, Trush MA, Li Y.

Exp Biol Med (Maywood). 2008 Apr;233(4):463-74. doi: 10.3181/0711-RM-304.

PMID:
18367636
3.

Antioxidant effects of diallyl trisulfide on high glucose-induced apoptosis are mediated by the PI3K/Akt-dependent activation of Nrf2 in cardiomyocytes.

Tsai CY, Wang CC, Lai TY, Tsu HN, Wang CH, Liang HY, Kuo WW.

Int J Cardiol. 2013 Sep 30;168(2):1286-97. doi: 10.1016/j.ijcard.2012.12.004. Epub 2013 Feb 27.

PMID:
23453443
4.

Phytochemical activation of Nrf2 protects human coronary artery endothelial cells against an oxidative challenge.

Donovan EL, McCord JM, Reuland DJ, Miller BF, Hamilton KL.

Oxid Med Cell Longev. 2012;2012:132931. doi: 10.1155/2012/132931. Epub 2012 May 22.

5.

Nrf2 is critical in defense against high glucose-induced oxidative damage in cardiomyocytes.

He X, Kan H, Cai L, Ma Q.

J Mol Cell Cardiol. 2009 Jan;46(1):47-58. doi: 10.1016/j.yjmcc.2008.10.007. Epub 2008 Nov 1.

PMID:
19007787
6.

Nrf2-dependent upregulation of antioxidative enzymes: a novel pathway for proteasome inhibitor-mediated cardioprotection.

Dreger H, Westphal K, Weller A, Baumann G, Stangl V, Meiners S, Stangl K.

Cardiovasc Res. 2009 Jul 15;83(2):354-61. doi: 10.1093/cvr/cvp107. Epub 2009 Apr 7.

PMID:
19351736
7.

An essential role of Nrf2 in American ginseng-mediated anti-oxidative actions in cardiomyocytes.

Li J, Ichikawa T, Jin Y, Hofseth LJ, Nagarkatti P, Nagarkatti M, Windust A, Cui T.

J Ethnopharmacol. 2010 Jul 20;130(2):222-30. doi: 10.1016/j.jep.2010.03.040. Epub 2010 May 4.

8.

Aspalathin Protects the Heart against Hyperglycemia-Induced Oxidative Damage by Up-Regulating Nrf2 Expression.

Dludla PV, Muller CJ, Joubert E, Louw J, Essop MF, Gabuza KB, Ghoor S, Huisamen B, Johnson R.

Molecules. 2017 Jan 14;22(1). pii: E129. doi: 10.3390/molecules22010129.

9.

Diabetic downregulation of Nrf2 activity via ERK contributes to oxidative stress-induced insulin resistance in cardiac cells in vitro and in vivo.

Tan Y, Ichikawa T, Li J, Si Q, Yang H, Chen X, Goldblatt CS, Meyer CJ, Li X, Cai L, Cui T.

Diabetes. 2011 Feb;60(2):625-33. doi: 10.2337/db10-1164.

10.

4-Hydroxynonenal induces Nrf2-mediated UCP3 upregulation in mouse cardiomyocytes.

López-Bernardo E, Anedda A, Sánchez-Pérez P, Acosta-Iborra B, Cadenas S.

Free Radic Biol Med. 2015 Nov;88(Pt B):427-438. doi: 10.1016/j.freeradbiomed.2015.03.032. Epub 2015 Apr 3.

PMID:
25843654
11.

Nrf2 protects against maladaptive cardiac responses to hemodynamic stress.

Li J, Ichikawa T, Villacorta L, Janicki JS, Brower GL, Yamamoto M, Cui T.

Arterioscler Thromb Vasc Biol. 2009 Nov;29(11):1843-50. doi: 10.1161/ATVBAHA.109.189480. Epub 2009 Jul 10.

PMID:
19592468
12.

Nrf2 controls bone marrow stromal cell susceptibility to oxidative and electrophilic stress.

Zhu H, Zhang L, Itoh K, Yamamoto M, Ross D, Trush MA, Zweier JL, Li Y.

Free Radic Biol Med. 2006 Jul 1;41(1):132-43. Epub 2006 Apr 1.

PMID:
16781461
13.

H2O2 preconditioning modulates phase II enzymes through p38 MAPK and PI3K/Akt activation.

Angeloni C, Motori E, Fabbri D, Malaguti M, Leoncini E, Lorenzini A, Hrelia S.

Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2196-205. doi: 10.1152/ajpheart.00934.2010. Epub 2011 Apr 8.

14.

Oxidative stress in health and disease: the therapeutic potential of Nrf2 activation.

Hybertson BM, Gao B, Bose SK, McCord JM.

Mol Aspects Med. 2011 Aug;32(4-6):234-46. doi: 10.1016/j.mam.2011.10.006. Epub 2011 Oct 15. Review.

15.

Resveratrol protects primary rat hepatocytes against oxidative stress damage: activation of the Nrf2 transcription factor and augmented activities of antioxidant enzymes.

Rubiolo JA, Mithieux G, Vega FV.

Eur J Pharmacol. 2008 Sep 4;591(1-3):66-72. doi: 10.1016/j.ejphar.2008.06.067. Epub 2008 Jun 22.

PMID:
18616940
17.

Eriodictyol-7-O-glucoside activates Nrf2 and protects against cerebral ischemic injury.

Jing X, Ren D, Wei X, Shi H, Zhang X, Perez RG, Lou H, Lou H.

Toxicol Appl Pharmacol. 2013 Dec 15;273(3):672-9.

PMID:
24466583
18.

DJ-1 Mediates the Delayed Cardioprotection of Hypoxic Preconditioning Through Activation of Nrf2 and Subsequent Upregulation of Antioxidative Enzymes.

Yan YF, Chen HP, Huang XS, Qiu LY, Liao ZP, Huang QR.

J Cardiovasc Pharmacol. 2015 Aug;66(2):148-58. doi: 10.1097/FJC.0000000000000257.

PMID:
25915512
19.

Activation of Nrf2-antioxidant signaling attenuates NFkappaB-inflammatory response and elicits apoptosis.

Li W, Khor TO, Xu C, Shen G, Jeong WS, Yu S, Kong AN.

Biochem Pharmacol. 2008 Dec 1;76(11):1485-9. doi: 10.1016/j.bcp.2008.07.017. Epub 2008 Jul 23. Review.

20.

Up-regulation of aldose reductase expression mediated by phosphatidylinositol 3-kinase/Akt and Nrf2 is involved in the protective effect of curcumin against oxidative damage.

Kang ES, Woo IS, Kim HJ, Eun SY, Paek KS, Kim HJ, Chang KC, Lee JH, Lee HT, Kim JH, Nishinaka T, Yabe-Nishimura C, Seo HG.

Free Radic Biol Med. 2007 Aug 15;43(4):535-45. Epub 2007 May 16.

PMID:
17640564

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