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Items: 1 to 20 of 97


Deciphering gene expression program of MAP3K1 in mouse eyelid morphogenesis.

Jin C, Chen J, Meng Q, Carreira V, Tam NN, Geh E, Karyala S, Ho SM, Zhou X, Medvedovic M, Xia Y.

Dev Biol. 2013 Feb 1;374(1):96-107. doi: 10.1016/j.ydbio.2012.11.020. Epub 2012 Nov 30.


Mitogen-activated protein kinase kinase kinase 1 (MAP3K1) integrates developmental signals for eyelid closure.

Geh E, Meng Q, Mongan M, Wang J, Takatori A, Zheng Y, Puga A, Lang RA, Xia Y.

Proc Natl Acad Sci U S A. 2011 Oct 18;108(42):17349-54. doi: 10.1073/pnas.1102297108. Epub 2011 Oct 3.


Gene-Environment Interactions Target Mitogen-activated Protein 3 Kinase 1 (MAP3K1) Signaling in Eyelid Morphogenesis.

Mongan M, Meng Q, Wang J, Kao WW, Puga A, Xia Y.

J Biol Chem. 2015 Aug 7;290(32):19770-9. doi: 10.1074/jbc.M115.665729. Epub 2015 Jun 24.


Expression of signaling components in embryonic eyelid epithelium.

Meng Q, Jin C, Chen Y, Chen J, Medvedovic M, Xia Y.

PLoS One. 2014 Feb 3;9(2):e87038. doi: 10.1371/journal.pone.0087038. eCollection 2014. Erratum in: PLoS One. 2014;9(8):e106783.


Epithelial sheet movement requires the cooperation of c-Jun and MAP3K1.

Meng Q, Mongan M, Wang J, Tang X, Zhang J, Kao W, Xia Y.

Dev Biol. 2014 Nov 1;395(1):29-37. doi: 10.1016/j.ydbio.2014.09.001. Epub 2014 Sep 16.


Repression of MAP3K1 expression and JNK activity by canonical Wnt signaling.

Meng Q, Mongan M, Wang J, Xia Y.

Dev Biol. 2018 Aug 15;440(2):129-136. doi: 10.1016/j.ydbio.2018.05.008. Epub 2018 May 19.


Eyelid closure in embryogenesis is required for ocular adnexa development.

Meng Q, Mongan M, Carreira V, Kurita H, Liu CY, Kao WW, Xia Y.

Invest Ophthalmol Vis Sci. 2014 Nov 6;55(11):7652-61. doi: 10.1167/iovs.14-15155.


Loss of MAP3K1 enhances proliferation and apoptosis during retinal development.

Mongan M, Wang J, Liu H, Fan Y, Jin C, Kao WY, Xia Y.

Development. 2011 Sep;138(18):4001-12. doi: 10.1242/dev.065003.


A role for MEK kinase 1 in TGF-beta/activin-induced epithelium movement and embryonic eyelid closure.

Zhang L, Wang W, Hayashi Y, Jester JV, Birk DE, Gao M, Liu CY, Kao WW, Karin M, Xia Y.

EMBO J. 2003 Sep 1;22(17):4443-54.


GPR48 regulates epithelial cell proliferation and migration by activating EGFR during eyelid development.

Jin C, Yin F, Lin M, Li H, Wang Z, Weng J, Liu M, Da Dong X, Qu J, Tu L.

Invest Ophthalmol Vis Sci. 2008 Oct;49(10):4245-53. doi: 10.1167/iovs.08-1860. Epub 2008 May 16.


Spry1 and Spry2 are necessary for eyelid closure.

Kuracha MR, Siefker E, Licht JD, Govindarajan V.

Dev Biol. 2013 Nov 15;383(2):227-38. doi: 10.1016/j.ydbio.2013.09.014. Epub 2013 Sep 17.


ADAM17 transactivates EGFR signaling during embryonic eyelid closure.

Hassemer EL, Endres B, Toonen JA, Ronchetti A, Dubielzig R, Sidjanin DJ.

Invest Ophthalmol Vis Sci. 2013 Jan 7;54(1):132-40. doi: 10.1167/iovs.12-11130.


Minor abnormalities of testis development in mice lacking the gene encoding the MAPK signalling component, MAP3K1.

Warr N, Bogani D, Siggers P, Brixey R, Tateossian H, Dopplapudi A, Wells S, Cheeseman M, Xia Y, Ostrer H, Greenfield A.

PLoS One. 2011 May 3;6(5):e19572. doi: 10.1371/journal.pone.0019572.


The goya mouse mutant reveals distinct newly identified roles for MAP3K1 in the development and survival of cochlear sensory hair cells.

Parker A, Cross SH, Jackson IJ, Hardisty-Hughes R, Morse S, Nicholson G, Coghill E, Bowl MR, Brown SD.

Dis Model Mech. 2015 Dec;8(12):1555-68. doi: 10.1242/dmm.023176. Epub 2015 Nov 5.


MAP3K1 function is essential for cytoarchitecture of the mouse organ of Corti and survival of auditory hair cells.

Yousaf R, Meng Q, Hufnagel RB, Xia Y, Puligilla C, Ahmed ZM, Riazuddin S.

Dis Model Mech. 2015 Dec;8(12):1543-53. doi: 10.1242/dmm.023077. Epub 2015 Oct 23.


HB-EGF promotes epithelial cell migration in eyelid development.

Mine N, Iwamoto R, Mekada E.

Development. 2005 Oct;132(19):4317-26. Epub 2005 Sep 1.


Differential transmission of MEKK1 morphogenetic signals by JNK1 and JNK2.

Takatori A, Geh E, Chen L, Zhang L, Meller J, Xia Y.

Development. 2008 Jan;135(1):23-32. Epub 2007 Nov 21.


A dual role of FGF10 in proliferation and coordinated migration of epithelial leading edge cells during mouse eyelid development.

Tao H, Shimizu M, Kusumoto R, Ono K, Noji S, Ohuchi H.

Development. 2005 Jul;132(14):3217-30. Epub 2005 Jun 15.


Wakayama Symposium: Epithelial-mesenchymal interactions in eyelid development.

Ohuchi H.

Ocul Surf. 2012 Oct;10(4):212-6. doi: 10.1016/j.jtos.2012.07.005. Epub 2012 Jul 25. Review.


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