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Items: 1 to 20 of 71

1.

Assessing the impact of child/adult differences in hepatic first-pass effect on the human kinetic adjustment factor for ingested toxicants.

Valcke M, Krishnan K.

Regul Toxicol Pharmacol. 2013 Feb;65(1):126-34. doi: 10.1016/j.yrtph.2012.11.006. Epub 2012 Nov 29.

PMID:
23200794
2.

An assessment of the impact of physico-chemical and biochemical characteristics on the human kinetic adjustment factor for systemic toxicants.

Valcke M, Krishnan K.

Toxicology. 2011 Aug 15;286(1-3):36-47. doi: 10.1016/j.tox.2011.05.003. Epub 2011 May 14.

PMID:
21605617
3.

Evaluation of the impact of the exposure route on the human kinetic adjustment factor.

Valcke M, Krishnan K.

Regul Toxicol Pharmacol. 2011 Mar;59(2):258-69. doi: 10.1016/j.yrtph.2010.10.008. Epub 2010 Oct 20.

PMID:
20969910
4.

Assessing the impact of the duration and intensity of inhalation exposure on the magnitude of the variability of internal dose metrics in children and adults.

Valcke M, Krishnan K.

Inhal Toxicol. 2011 Dec;23(14):863-77. doi: 10.3109/08958378.2011.609918. Epub 2011 Nov 15.

PMID:
22084919
5.

Modeling interchild differences in pharmacokinetics on the basis of subject-specific data on physiology and hepatic CYP2E1 levels: a case study with toluene.

Nong A, McCarver DG, Hines RN, Krishnan K.

Toxicol Appl Pharmacol. 2006 Jul 1;214(1):78-87. Epub 2006 Feb 7.

PMID:
16464483
6.
7.

Characterization of the human kinetic adjustment factor for the health risk assessment of environmental contaminants.

Valcke M, Krishnan K.

J Appl Toxicol. 2014 Mar;34(3):227-40. doi: 10.1002/jat.2919. Epub 2013 Sep 13. Review.

PMID:
24038072
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13.

Probabilistic framework for the estimation of the adult and child toxicokinetic intraspecies uncertainty factors.

Pelekis M, Nicolich MJ, Gauthier JS.

Risk Anal. 2003 Dec;23(6):1239-55.

PMID:
14641898
14.

Ontogeny of hepatic CYP1A2 and CYP2E1 expression in rat.

Elbarbry FA, McNamara PJ, Alcorn J.

J Biochem Mol Toxicol. 2007;21(1):41-50.

PMID:
17366540
15.
16.

Incorporating pharmacokinetic differences between children and adults in assessing children's risks to environmental toxicants.

Ginsberg G, Hattis D, Sonawane B.

Toxicol Appl Pharmacol. 2004 Jul 15;198(2):164-83. Review.

PMID:
15236952
17.

Impact of the 1990 Hong Kong legislation for restriction on sulfur content in fuel.

Wong CM, Rabl A, Thach TQ, Chau YK, Chan KP, Cowling BJ, Lai HK, Lam TH, McGhee SM, Anderson HR, Hedley AJ.

Res Rep Health Eff Inst. 2012 Aug;(170):5-91.

PMID:
23316618
18.

Azide inhibits human cytochrome P -4502E1, 1A2, and 3A4.

Salmela KS, Tsyrlov IB, Lieber CS.

Alcohol Clin Exp Res. 2001 Feb;25(2):253-60.

PMID:
11236840
19.

Multicity study of air pollution and mortality in Latin America (the ESCALA study).

Romieu I, Gouveia N, Cifuentes LA, de Leon AP, Junger W, Vera J, Strappa V, Hurtado-Díaz M, Miranda-Soberanis V, Rojas-Bracho L, Carbajal-Arroyo L, Tzintzun-Cervantes G; HEI Health Review Committee.

Res Rep Health Eff Inst. 2012 Oct;(171):5-86.

PMID:
23311234
20.

Impact of inter-individual differences in drug metabolism and pharmacokinetics on safety evaluation.

Dorne JL.

Fundam Clin Pharmacol. 2004 Dec;18(6):609-20. Review.

PMID:
15548231

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