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Items: 1 to 20 of 166

1.

Targeting the molecular chaperone heat shock protein 90 (HSP90): lessons learned and future directions.

Hong DS, Banerji U, Tavana B, George GC, Aaron J, Kurzrock R.

Cancer Treat Rev. 2013 Jun;39(4):375-87. doi: 10.1016/j.ctrv.2012.10.001. Epub 2012 Nov 28. Review.

PMID:
23199899
2.

Drug-mediated targeted disruption of multiple protein activities through functional inhibition of the Hsp90 chaperone complex.

Stravopodis DJ, Margaritis LH, Voutsinas GE.

Curr Med Chem. 2007;14(29):3122-38. Review.

PMID:
18220746
3.

Anticancer Inhibitors of Hsp90 Function: Beyond the Usual Suspects.

Garg G, Khandelwal A, Blagg BS.

Adv Cancer Res. 2016;129:51-88. doi: 10.1016/bs.acr.2015.12.001. Epub 2016 Feb 10. Review.

PMID:
26916001
4.

Discovery and development of heat shock protein 90 inhibitors as anticancer agents: a review of patented potent geldanamycin derivatives.

Kim T, Keum G, Pae AN.

Expert Opin Ther Pat. 2013 Aug;23(8):919-43. doi: 10.1517/13543776.2013.780597. Epub 2013 May 4. Review.

PMID:
23641970
5.

The therapeutic target Hsp90 and cancer hallmarks.

Miyata Y, Nakamoto H, Neckers L.

Curr Pharm Des. 2013;19(3):347-65. Review.

PMID:
22920906
6.

Hsp90 inhibitors as anti-cancer agents, from basic discoveries to clinical development.

Soga S, Akinaga S, Shiotsu Y.

Curr Pharm Des. 2013;19(3):366-76. Review.

PMID:
22920907
7.

Heat-shock protein 90 inhibitors as antitumor agents: a survey of the literature from 2005 to 2010.

Messaoudi S, Peyrat JF, Brion JD, Alami M.

Expert Opin Ther Pat. 2011 Oct;21(10):1501-42. doi: 10.1517/13543776.2011.594041. Epub 2011 Jun 21. Review.

PMID:
21689065
8.

Recent advances in Hsp90 inhibitors as antitumor agents.

Messaoudi S, Peyrat JF, Brion JD, Alami M.

Anticancer Agents Med Chem. 2008 Oct;8(7):761-82. Review.

PMID:
18855578
9.
10.
11.

Targeting of multiple signalling pathways by heat shock protein 90 molecular chaperone inhibitors.

Powers MV, Workman P.

Endocr Relat Cancer. 2006 Dec;13 Suppl 1:S125-35. Review.

12.

Heat shock protein 90 inhibitors as therapeutic agents.

Gomez-Monterrey I, Sala M, Musella S, Campiglia P.

Recent Pat Anticancer Drug Discov. 2012 Sep;7(3):313-36. Review.

PMID:
22338602
13.

Heat shock protein 90 inhibitors in the treatment of cancer: current status and future directions.

Jhaveri K, Ochiana SO, Dunphy MP, Gerecitano JF, Corben AD, Peter RI, Janjigian YY, Gomes-DaGama EM, Koren J 3rd, Modi S, Chiosis G.

Expert Opin Investig Drugs. 2014 May;23(5):611-28. doi: 10.1517/13543784.2014.902442. Epub 2014 Mar 26. Review.

14.

Heat Shock Protein 90 Inhibition in Cancer Drug Discovery: From Chemistry to Futural Clinical Applications.

Özgür A, Tutar Y.

Anticancer Agents Med Chem. 2016;16(3):280-90. Review.

PMID:
26295332
15.

Hsp90: an emerging target for breast cancer therapy.

Beliakoff J, Whitesell L.

Anticancer Drugs. 2004 Aug;15(7):651-62. Review.

PMID:
15269596
16.

Heat-shock protein 90 inhibitors in antineoplastic therapy: is it all wrapped up?

Isaacs JS.

Expert Opin Investig Drugs. 2005 Jun;14(6):569-89. Review.

PMID:
16004589
17.

Extracellular heat shock protein 90: a role for a molecular chaperone in cell motility and cancer metastasis.

Tsutsumi S, Neckers L.

Cancer Sci. 2007 Oct;98(10):1536-9. Epub 2007 Jul 23. Review.

18.

Targeting multiple signal transduction pathways through inhibition of Hsp90.

Zhang H, Burrows F.

J Mol Med (Berl). 2004 Aug;82(8):488-99. Epub 2004 May 27. Review.

PMID:
15168026
19.

Heat-shock protein 90 inhibitors in cancer therapy: 17AAG and beyond.

Georgakis GV, Younes A.

Future Oncol. 2005 Apr;1(2):273-81. Review.

PMID:
16555999
20.

NVP-AUY922: a small molecule HSP90 inhibitor with potent antitumor activity in preclinical breast cancer models.

Jensen MR, Schoepfer J, Radimerski T, Massey A, Guy CT, Brueggen J, Quadt C, Buckler A, Cozens R, Drysdale MJ, Garcia-Echeverria C, Chène P.

Breast Cancer Res. 2008;10(2):R33. doi: 10.1186/bcr1996. Epub 2008 Apr 22.

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